Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   E0F39_RS02825 Genome accession   NZ_LR216060
Coordinates   515809..517485 (-) Length   558 a.a.
NCBI ID   WP_306293384.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain GPSC47 substr. ST315     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 510809..522485
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F39_RS02780 (SAMEA3713867_00518) - 510918..511247 (-) 330 WP_000132572.1 hypothetical protein -
  E0F39_RS02785 (SAMEA3713867_00519) - 511523..511861 (+) 339 WP_000682133.1 LytTR family DNA-binding domain-containing protein -
  E0F39_RS02790 (SAMEA3713867_00520) comE/blpR 511866..512603 (+) 738 WP_001219137.1 response regulator transcription factor Regulator
  E0F39_RS02795 (SAMEA3713867_00521) - 512617..513957 (+) 1341 WP_001099893.1 sensor histidine kinase -
  E0F39_RS02800 (SAMEA3713867_00522) blpC 514001..514156 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  E0F39_RS02805 (SAMEA3713867_00523) - 514213..514935 (-) 723 Protein_534 HlyD family efflux transporter periplasmic adaptor subunit -
  E0F39_RS02815 - 515044..515142 (+) 99 Protein_535 IS5/IS1182 family transposase -
  E0F39_RS02820 (SAMEA3713867_00524) - 515160..515798 (-) 639 Protein_536 bacteriocin ABC transporter ATP-binding protein -
  E0F39_RS02825 (SAMEA3713867_00525) comA/nlmT 515809..517485 (-) 1677 WP_306293384.1 peptide cleavage/export ABC transporter Regulator
  E0F39_RS13135 (SAMEA3713867_00526) comA/nlmT 517379..517966 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  E0F39_RS02835 (SAMEA3713867_00527) - 518240..518443 (+) 204 WP_001093262.1 bacteriocin class II family protein -
  E0F39_RS02840 (SAMEA3713867_00528) - 518761..518964 (+) 204 WP_000411016.1 hypothetical protein -
  E0F39_RS02850 - 519967..520771 (+) 805 Protein_541 IS5 family transposase -
  E0F39_RS02855 (SAMEA3713867_00532) blpM 520924..521178 (+) 255 WP_000379878.1 two-peptide bacteriocin subunit BlpM -
  E0F39_RS02860 (SAMEA3713867_00533) blpN 521194..521397 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  E0F39_RS02870 (SAMEA3713867_00534) - 521641..521874 (+) 234 WP_000379963.1 hypothetical protein -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62975.28 Da        Isoelectric Point: 6.7308

>NTDB_id=1126176 E0F39_RS02825 WP_306293384.1 515809..517485(-) (comA/nlmT) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=1126176 E0F39_RS02825 WP_306293384.1 515809..517485(-) (comA/nlmT) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATCCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTTTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTCGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATTATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTGTTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(10-279)

ABC transporter (ABC_tran)

(341-490)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.25

99.821

0.731
  comA Streptococcus mitis NCTC 12261

67.742

100

0.677
  comA Streptococcus pneumoniae D39

67.384

100

0.674
  comA Streptococcus pneumoniae R6

67.384

100

0.674
  comA Streptococcus pneumoniae Rx1

67.384

100

0.674
  comA Streptococcus gordonii str. Challis substr. CH1

67.084

100

0.672
  comA Streptococcus mitis SK321

67.204

100

0.672
  comA Streptococcus pneumoniae TIGR4

67.025

100

0.67

Multiple sequence alignment