Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   E0F39_RS13135 Genome accession   NZ_LR216060
Coordinates   517379..517966 (-) Length   195 a.a.
NCBI ID   WP_000205166.1    Uniprot ID   Q9ETN5
Organism   Streptococcus pneumoniae strain GPSC47 substr. ST315     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 512379..522966
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E0F39_RS02795 (SAMEA3713867_00521) - 512617..513957 (+) 1341 WP_001099893.1 sensor histidine kinase -
  E0F39_RS02800 (SAMEA3713867_00522) blpC 514001..514156 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  E0F39_RS02805 (SAMEA3713867_00523) - 514213..514935 (-) 723 Protein_534 HlyD family efflux transporter periplasmic adaptor subunit -
  E0F39_RS02815 - 515044..515142 (+) 99 Protein_535 IS5/IS1182 family transposase -
  E0F39_RS02820 (SAMEA3713867_00524) - 515160..515798 (-) 639 Protein_536 bacteriocin ABC transporter ATP-binding protein -
  E0F39_RS02825 (SAMEA3713867_00525) comA/nlmT 515809..517485 (-) 1677 WP_306293384.1 peptide cleavage/export ABC transporter Regulator
  E0F39_RS13135 (SAMEA3713867_00526) comA/nlmT 517379..517966 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  E0F39_RS02835 (SAMEA3713867_00527) - 518240..518443 (+) 204 WP_001093262.1 bacteriocin class II family protein -
  E0F39_RS02840 (SAMEA3713867_00528) - 518761..518964 (+) 204 WP_000411016.1 hypothetical protein -
  E0F39_RS02850 - 519967..520771 (+) 805 Protein_541 IS5 family transposase -
  E0F39_RS02855 (SAMEA3713867_00532) blpM 520924..521178 (+) 255 WP_000379878.1 two-peptide bacteriocin subunit BlpM -
  E0F39_RS02860 (SAMEA3713867_00533) blpN 521194..521397 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  E0F39_RS02870 (SAMEA3713867_00534) - 521641..521874 (+) 234 WP_000379963.1 hypothetical protein -
  E0F39_RS02875 (SAMEA3713867_00535) - 521906..522595 (+) 690 WP_000760523.1 CPBP family intramembrane glutamic endopeptidase -
  E0F39_RS02880 (SAMEA3713867_00536) blpZ 522637..522870 (+) 234 WP_000276498.1 immunity protein BlpZ -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22270.71 Da        Isoelectric Point: 9.6188

>NTDB_id=1126239 E0F39_RS13135 WP_000205166.1 517379..517966(-) (comA/nlmT) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide


Download         Length: 588 bp        

>NTDB_id=1126239 E0F39_RS13135 WP_000205166.1 517379..517966(-) (comA/nlmT) [Streptococcus pneumoniae strain GPSC47 substr. ST315]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGTAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9ETN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

59.89

93.333

0.559
  comA Streptococcus mitis NCTC 12261

54.891

94.359

0.518
  comA Streptococcus mitis SK321

54.348

94.359

0.513
  comA Streptococcus pneumoniae TIGR4

53.804

94.359

0.508
  comA Streptococcus pneumoniae Rx1

53.804

94.359

0.508
  comA Streptococcus pneumoniae D39

53.804

94.359

0.508
  comA Streptococcus pneumoniae R6

53.804

94.359

0.508
  comA Streptococcus gordonii str. Challis substr. CH1

52.717

94.359

0.497

Multiple sequence alignment