Detailed information NTG1123632

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: EL254_RS05285
• Genome accession: NZ_LR134512
• Coordinates: 1002535..1003377 (-)
• Length: 280 a.a.
• NCBI ID: WP_001015243.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain NCTC13949
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 997535..1008377

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL254_RS05275 (NCTC13949_01055)	-	999483..1000184 (-)	702	WP_000120349.1	ABC transporter ATP-binding protein	-
EL254_RS05280 (NCTC13949_01056)	topA	1000320..1002440 (-)	2121	WP_050896390.1	type I DNA topoisomerase	-
EL254_RS05285 (NCTC13949_01057)	dprA	1002535..1003377 (-)	843	WP_001015243.1	DNA-processing protein DprA	Machinery gene
EL254_RS05290 (NCTC13949_01058)	-	1003515..1004543 (-)	1029	WP_000162764.1	siderophore ABC transporter substrate-binding protein	-
EL254_RS05295 (NCTC13949_01059)	-	1004605..1005366 (-)	762	WP_000614756.1	ABC transporter ATP-binding protein	-
EL254_RS05300 (NCTC13949_01060)	-	1005363..1006337 (-)	975	WP_126418188.1	iron chelate uptake ABC transporter family permease subunit	-
EL254_RS05305 (NCTC13949_01061)	-	1006334..1007296 (-)	963	WP_126418189.1	ABC transporter permease	-
EL254_RS05310 (NCTC13949_01062)	-	1007536..1008084 (-)	549	WP_000136503.1	sugar O-acetyltransferase	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31241.30 Da
• Isoelectric Point: 9.3800

>NTDB_id=1123632 EL254_RS05285 WP_001015243.1 1002535..1003377(-) (dprA) [Streptococcus agalactiae strain NCTC13949]
MNHFELFKLKKAGLTNLNINNIINYLKKNSITSLSVRNMAVVSKCKNPTFFIENYKQLDLKKLRQEFKKFPVLSILDSNY
PLELKEIYNPPVLLFYQGNIELLSKPKLAVVGARQASQIGCQSVKKIIKETNNQFVIVSGLARGIDTAAHVSALKNGGSS
IAVIGSGLDVYYPTENKKLQEYMSYNHLVLSEYFAGEQPLKFHFPERNRIIAGLCQGIVVAEAKMRSGSLITCERALEEG
REVFAIPGNIIDGKSDGCHHLIQEGAKCIISGKDILSEYQ

Nucleotide

• Length: 843 bp

>NTDB_id=1123632 EL254_RS05285 WP_001015243.1 1002535..1003377(-) (dprA) [Streptococcus agalactiae strain NCTC13949]
ATGAATCATTTTGAACTATTTAAGCTTAAAAAAGCTGGACTAACAAATCTTAATATCAACAATATTATCAACTATCTCAA
AAAGAATAGTATAACTTCTCTATCTGTTCGCAATATGGCCGTAGTGTCAAAATGTAAAAATCCTACTTTCTTTATAGAAA
ATTATAAACAGCTAGACCTTAAAAAACTTCGACAAGAATTCAAAAAATTTCCAGTTCTATCGATTTTGGATTCTAACTAT
CCTTTAGAGTTAAAAGAAATATATAATCCACCAGTTCTACTTTTTTATCAGGGTAATATTGAACTTCTATCTAAACCTAA
ATTAGCTGTAGTGGGGGCAAGACAGGCATCTCAGATAGGTTGTCAGTCTGTTAAAAAGATTATCAAGGAGACTAACAATC
AATTTGTTATCGTAAGTGGTTTAGCGCGTGGCATTGATACAGCAGCACATGTTAGTGCTTTAAAAAATGGCGGCAGTAGT
ATAGCTGTTATAGGGAGTGGTTTAGATGTTTATTATCCAACGGAGAATAAGAAACTTCAAGAATATATGTCATATAATCA
TCTCGTATTATCAGAATATTTCGCCGGAGAACAACCCTTGAAATTTCATTTCCCCGAACGTAACCGTATTATTGCAGGGC
TGTGCCAAGGTATTGTGGTTGCCGAAGCTAAGATGAGATCTGGAAGTTTAATTACCTGTGAAAGAGCATTAGAAGAGGGA
CGAGAAGTTTTTGCCATTCCCGGAAATATTATCGATGGCAAATCAGATGGATGCCACCATCTTATCCAAGAAGGAGCTAA
ATGCATTATTTCAGGAAAAGATATCCTTTCTGAATATCAGTAG

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (69-270)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-63)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	70.609	99.643	0.704
dprA/cilB/dalA	Streptococcus mitis SK321	62.5	100	0.625
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae D39	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae R6	61.786	100	0.618
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	61.786	100	0.618
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	61.429	100	0.614
dprA	Lactococcus lactis subsp. cremoris KW2	61.29	99.643	0.611
dprA	Latilactobacillus sakei subsp. sakei 23K	41.833	89.643	0.375
dprA	Haemophilus influenzae Rd KW20	37.132	97.143	0.361