Detailed information NTG1122029

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: EL147_RS08640
• Genome accession: NZ_LR134341
• Coordinates: 1757574..1758164 (+)
• Length: 196 a.a.
• NCBI ID: WP_003083781.1
• Uniprot ID: A0A4V0H7V7
• Organism: Streptococcus pseudoporcinus strain NCTC13786
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1752574..1763164

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL147_RS08625 (NCTC13786_01732)	-	1753326..1754783 (-)	1458	WP_007896270.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
EL147_RS08630 (NCTC13786_01733)	-	1754870..1756504 (+)	1635	WP_007895894.1	polysaccharide biosynthesis protein	-
EL147_RS08635 (NCTC13786_01734)	upp	1756734..1757363 (+)	630	WP_007895697.1	uracil phosphoribosyltransferase	-
EL147_RS08640 (NCTC13786_01735)	clpP	1757574..1758164 (+)	591	WP_003083781.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
EL147_RS08645 (NCTC13786_01736)	-	1758454..1758930 (+)	477	WP_007895841.1	YlbF family regulator	-
EL147_RS08650 (NCTC13786_01737)	-	1758900..1759148 (+)	249	WP_007895846.1	DUF2129 domain-containing protein	-
EL147_RS08655 (NCTC13786_01738)	-	1759303..1760475 (+)	1173	WP_007895732.1	ABC transporter substrate-binding protein	-
EL147_RS08660 (NCTC13786_01739)	-	1760519..1761388 (+)	870	WP_007895701.1	branched-chain amino acid ABC transporter permease	-
EL147_RS08665 (NCTC13786_01740)	-	1761391..1762344 (+)	954	WP_007895798.1	branched-chain amino acid ABC transporter permease	-
EL147_RS08670 (NCTC13786_01741)	-	1762345..1763109 (+)	765	WP_007895704.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21743.01 Da
• Isoelectric Point: 4.8856

>NTDB_id=1122029 EL147_RS08640 WP_003083781.1 1757574..1758164(+) (clpP) [Streptococcus pseudoporcinus strain NCTC13786]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGAGSGTQQTDMAIVAEQLLKTRKRLEKILADNSGK
TIKQIHKDAERDYWMDAKETLEYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=1122029 EL147_RS08640 WP_003083781.1 1757574..1758164(+) (clpP) [Streptococcus pseudoporcinus strain NCTC13786]
ATGATTCCTGTAGTTATTGAACAAACAAGTCGCGGAGAACGTTCTTATGATATCTATTCACGTCTCCTAAAAGATCGTAT
TATTATGCTAACTGGACCAGTTGAAGATAATATGGCAAATTCTATTATTGCACAGTTACTATTTTTGGACGCGCAAGATA
ATACTAAAGATATTTACCTCTATGTAAATACACCCGGAGGATCGGTTTCAGCTGGGTTAGCAATTGTTGATACGATGAAC
TTTATTAAATCAGATGTTCAAACGATTGTTATGGGGATGGCTGCCTCAATGGGAACGATCATTGCATCATCAGGTGCCAA
AGGTAAACGATTCATGCTACCAAATGCTGAATACTTAATTCATCAACCGATGGGGGGCGCTGGTAGTGGTACGCAACAAA
CAGATATGGCAATTGTTGCTGAACAATTGTTAAAAACACGGAAACGCCTTGAAAAAATCCTTGCTGATAATTCTGGTAAG
ACTATTAAACAAATTCACAAAGATGCAGAACGTGACTACTGGATGGATGCCAAAGAAACATTGGAATATGGCTTCATTGA
TGAAATCATGGAAAATAATGAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A4V0H7V7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	94.898	100	0.949
clpP	Streptococcus pyogenes JRS4	92.347	100	0.923
clpP	Streptococcus pyogenes MGAS315	92.347	100	0.923
clpP	Lactococcus lactis subsp. cremoris KW2	91.837	100	0.918
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	91.327	100	0.913
clpP	Streptococcus thermophilus LMD-9	89.286	100	0.893
clpP	Streptococcus thermophilus LMG 18311	89.286	100	0.893
clpP	Streptococcus pneumoniae Rx1	87.692	99.49	0.872
clpP	Streptococcus pneumoniae D39	87.692	99.49	0.872
clpP	Streptococcus pneumoniae R6	87.692	99.49	0.872
clpP	Streptococcus pneumoniae TIGR4	87.692	99.49	0.872
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.513	98.469	0.566
clpP	Bacillus subtilis subsp. subtilis str. 168	56.122	100	0.561