Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   EL147_RS01325 Genome accession   NZ_LR134341
Coordinates   267794..268468 (-) Length   224 a.a.
NCBI ID   WP_007893281.1    Uniprot ID   G5KBZ9
Organism   Streptococcus pseudoporcinus strain NCTC13786     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 262794..273468
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL147_RS01300 (NCTC13786_00261) - 263054..264331 (-) 1278 WP_007893025.1 pyrimidine-nucleoside phosphorylase -
  EL147_RS01305 (NCTC13786_00262) - 264328..264918 (-) 591 WP_007893359.1 class I SAM-dependent methyltransferase -
  EL147_RS01310 (NCTC13786_00263) coaA 265184..266104 (+) 921 WP_007893324.1 type I pantothenate kinase -
  EL147_RS01315 (NCTC13786_00264) rpsT 266164..266406 (+) 243 WP_077321972.1 30S ribosomal protein S20 -
  EL147_RS01320 (NCTC13786_00265) ciaH 266482..267801 (-) 1320 WP_007893273.1 cell wall metabolism sensor histidine kinase WalK Regulator
  EL147_RS01325 (NCTC13786_00266) ciaR 267794..268468 (-) 675 WP_007893281.1 response regulator transcription factor Regulator
  EL147_RS01330 (NCTC13786_00267) - 268821..271370 (-) 2550 WP_007893092.1 M1 family metallopeptidase -
  EL147_RS01335 (NCTC13786_00268) phoU 271445..272098 (-) 654 WP_007893157.1 phosphate signaling complex protein PhoU -
  EL147_RS01340 (NCTC13786_00269) pstB 272126..272884 (-) 759 WP_007893365.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25531.33 Da        Isoelectric Point: 4.3945

>NTDB_id=1121991 EL147_RS01325 WP_007893281.1 267794..268468(-) (ciaR) [Streptococcus pseudoporcinus strain NCTC13786]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGDEGLYEAESGVYDLILLDLMLPEKNGFQVLKELREKDIKTPVLIMTA
KEGLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRTGKFNENSITFGNLRVDLDRNAVKVNGSAVELLGKEYDLLIY
LLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKDTDFATNLQTLRSVGYILKAND

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1121991 EL147_RS01325 WP_007893281.1 267794..268468(-) (ciaR) [Streptococcus pseudoporcinus strain NCTC13786]
ATGATAAAAATATTACTAGTTGAAGATGATTTAAGTTTATCGAATTCTATTTTTGACTTTCTCGATGATTTTGCTGATGT
TATGCAAGTTTTTGATGGAGATGAAGGTTTATATGAAGCAGAAAGTGGGGTTTATGATTTAATTCTTTTAGATTTAATGC
TCCCAGAAAAAAATGGCTTTCAAGTTCTAAAAGAGCTTAGAGAAAAGGATATTAAGACCCCTGTTTTAATTATGACTGCT
AAAGAAGGGTTAGATGATAAGGGACATGGTTTTGAATTAGGTGCTGATGACTATTTAACCAAGCCTTTTTACTTGGAAGA
ACTTAAAATGCGCATTCAAGCCCTTCTTAAACGAACTGGTAAGTTTAACGAAAACAGTATTACGTTTGGTAATCTCAGAG
TTGACCTTGATCGGAATGCTGTGAAAGTGAATGGTAGTGCCGTTGAACTATTAGGGAAAGAATATGATCTGCTCATCTAT
TTACTTCAAAATCAGAATGTTATTTTACCGAAATCCCAAATTTTTGATCGGATTTGGGGTTTTGATAGTGATACCACTAT
CTCGGTCGTGGAAGTTTATGTGTCTAAAATTCGAAAGAAATTAAAAGATACTGATTTTGCAACAAACTTACAGACCTTAC
GTAGCGTTGGCTACATTTTAAAAGCCAATGACTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(146-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5KBZ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

89.14

98.661

0.879
  ciaR Streptococcus pneumoniae Rx1

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae D39

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae R6

86.425

98.661

0.853
  ciaR Streptococcus pneumoniae TIGR4

86.425

98.661

0.853
  vicR Streptococcus mutans UA159

36.864

100

0.388
  covR Lactococcus lactis subsp. lactis strain DGCC12653

37.778

100

0.379
  micA Streptococcus pneumoniae Cp1015

34.615

100

0.362

Multiple sequence alignment