Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   EL147_RS01320 Genome accession   NZ_LR134341
Coordinates   266482..267801 (-) Length   439 a.a.
NCBI ID   WP_007893273.1    Uniprot ID   G5KBZ8
Organism   Streptococcus pseudoporcinus strain NCTC13786     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 261482..272801
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL147_RS01290 (NCTC13786_00259) - 262006..262395 (-) 390 WP_007893088.1 cytidine deaminase -
  EL147_RS01295 (NCTC13786_00260) deoC 262382..263044 (-) 663 WP_007893385.1 deoxyribose-phosphate aldolase -
  EL147_RS01300 (NCTC13786_00261) - 263054..264331 (-) 1278 WP_007893025.1 pyrimidine-nucleoside phosphorylase -
  EL147_RS01305 (NCTC13786_00262) - 264328..264918 (-) 591 WP_007893359.1 class I SAM-dependent methyltransferase -
  EL147_RS01310 (NCTC13786_00263) coaA 265184..266104 (+) 921 WP_007893324.1 type I pantothenate kinase -
  EL147_RS01315 (NCTC13786_00264) rpsT 266164..266406 (+) 243 WP_077321972.1 30S ribosomal protein S20 -
  EL147_RS01320 (NCTC13786_00265) ciaH 266482..267801 (-) 1320 WP_007893273.1 cell wall metabolism sensor histidine kinase WalK Regulator
  EL147_RS01325 (NCTC13786_00266) ciaR 267794..268468 (-) 675 WP_007893281.1 response regulator transcription factor Regulator
  EL147_RS01330 (NCTC13786_00267) - 268821..271370 (-) 2550 WP_007893092.1 M1 family metallopeptidase -
  EL147_RS01335 (NCTC13786_00268) phoU 271445..272098 (-) 654 WP_007893157.1 phosphate signaling complex protein PhoU -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50266.68 Da        Isoelectric Point: 9.0860

>NTDB_id=1121990 EL147_RS01320 WP_007893273.1 266482..267801(-) (ciaH) [Streptococcus pseudoporcinus strain NCTC13786]
MTKYRAIITSDNFDRFFHFFAVFTGIFVVMTVIILQIMKVGVYSSVDTSLTAVATHSTLYANRTMERISSFYFDGQDFNF
KTNLDDLKGKNSDQPVANTDIILFNANGMVINTFDALSNFQNFSFKKSDLNEIKTRKLVNYYGHEEKFHTITVRVHSNNY
PAVAYLMAVVNVEQSEKTNERYEKIIIIIMILFWLISILASIYLANWSNKPILESYEKQKMFVENASHELRTPLAVLQNR
LETLFRKPNESILDNSEAIASSLEEVRNMRILTTNLLNLARRDDGIKPEIVEISSHFFDGIFDNYKLIAEDYGKGFESVN
GVTKPIRMDKSLLKQLMTILFDNAIKYTDESGFIKITVRNTDKYFFITVEDNGPGIRDADKKKIFDRFYRVDKARTRSHG
GFGLGLSLAQQIVTSLKGTILVNDNKGKGSVFEVKLPLN

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=1121990 EL147_RS01320 WP_007893273.1 266482..267801(-) (ciaH) [Streptococcus pseudoporcinus strain NCTC13786]
ATGACTAAATACAGAGCTATTATTACATCAGATAATTTTGACCGTTTCTTTCATTTCTTTGCCGTTTTTACAGGTATATT
TGTTGTTATGACGGTTATTATTCTGCAAATTATGAAAGTGGGCGTTTACTCATCAGTAGATACAAGCTTGACAGCTGTTG
CGACTCATTCAACCCTCTATGCTAATCGAACTATGGAAAGGATTTCCTCTTTCTATTTTGATGGTCAAGACTTCAATTTT
AAAACAAATCTAGATGATTTAAAGGGGAAAAATAGTGATCAACCCGTCGCAAATACTGATATTATTTTATTTAATGCTAA
TGGTATGGTGATTAATACCTTTGATGCGCTTTCTAATTTTCAAAATTTCTCTTTTAAAAAGAGTGATTTAAACGAAATTA
AAACCAGGAAATTGGTTAATTATTACGGTCATGAGGAAAAATTTCATACTATTACGGTTAGAGTTCATTCTAACAACTAC
CCAGCTGTTGCTTATTTAATGGCTGTTGTGAACGTAGAGCAATCTGAAAAAACGAATGAACGCTATGAAAAAATAATCAT
TATCATTATGATTCTATTTTGGCTTATTTCTATTTTGGCAAGTATCTATTTAGCCAATTGGAGTAACAAACCAATTCTCG
AAAGCTATGAAAAACAGAAGATGTTTGTTGAAAATGCCAGTCATGAATTAAGAACGCCTTTGGCTGTGCTCCAAAATCGT
TTAGAAACCCTTTTTCGCAAGCCCAATGAGAGTATTTTGGATAATAGCGAAGCAATTGCCTCAAGCTTGGAAGAGGTTCG
AAACATGAGAATATTAACAACTAATCTTCTGAACTTAGCTCGTCGGGATGATGGTATTAAACCTGAAATTGTAGAAATAT
CGAGTCACTTTTTTGATGGTATTTTTGACAATTATAAACTCATTGCTGAAGATTATGGAAAAGGTTTTGAGTCTGTTAAT
GGCGTTACTAAGCCAATTAGAATGGATAAGTCCCTTCTAAAACAATTAATGACAATTTTATTCGATAATGCAATTAAATA
TACAGATGAATCAGGTTTTATTAAAATCACTGTTAGAAATACAGATAAATATTTCTTTATTACTGTTGAAGATAATGGAC
CGGGGATTAGAGATGCTGATAAAAAGAAAATATTTGACCGTTTTTATCGAGTAGATAAAGCAAGAACAAGAAGTCATGGT
GGCTTTGGATTAGGTTTGTCACTGGCTCAACAAATTGTCACTTCCTTAAAGGGGACTATTCTTGTTAATGATAATAAAGG
CAAGGGGAGTGTCTTTGAGGTTAAACTTCCTCTAAATTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-438)

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5KBZ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

56.136

100

0.563
  ciaH Streptococcus pneumoniae Rx1

47.534

100

0.483
  ciaH Streptococcus pneumoniae D39

47.534

100

0.483
  ciaH Streptococcus pneumoniae R6

47.534

100

0.483
  ciaH Streptococcus pneumoniae TIGR4

47.534

100

0.483

Multiple sequence alignment