Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   EL140_RS02855 Genome accession   NZ_LR134336
Coordinates   567837..568427 (+) Length   196 a.a.
NCBI ID   WP_000613467.1    Uniprot ID   A0AAX0N3L0
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 565902..577351 567837..568427 within 0


Gene organization within MGE regions


Location: 565902..577351
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS02840 (NCTC11427_00558) - 565902..566459 (+) 558 WP_000003897.1 TetR/AcrR family transcriptional regulator -
  EL140_RS02845 (NCTC11427_00559) - 566478..566945 (+) 468 WP_000136994.1 deoxycytidylate deaminase -
  EL140_RS02850 (NCTC11427_00560) upp 567034..567663 (+) 630 WP_000515974.1 uracil phosphoribosyltransferase -
  EL140_RS02855 (NCTC11427_00561) clpP 567837..568427 (+) 591 WP_000613467.1 ATP-dependent Clp protease proteolytic subunit ClpP Regulator
  EL140_RS02865 (NCTC11427_00562) - 568506..568775 (+) 270 WP_000462100.1 YlbG family protein -
  EL140_RS02870 (NCTC11427_00563) - 568864..570024 (+) 1161 WP_000726132.1 ABC transporter substrate-binding protein -
  EL140_RS02875 (NCTC11427_00564) - 570144..571013 (+) 870 WP_000941413.1 branched-chain amino acid ABC transporter permease -
  EL140_RS02880 (NCTC11427_00565) - 571017..571973 (+) 957 WP_000856260.1 branched-chain amino acid ABC transporter permease -
  EL140_RS02885 (NCTC11427_00566) - 571973..572737 (+) 765 WP_001186014.1 ABC transporter ATP-binding protein -
  EL140_RS02890 (NCTC11427_00567) - 572737..573447 (+) 711 WP_000062204.1 ABC transporter ATP-binding protein -
  EL140_RS02895 (NCTC11427_00568) - 573860..574516 (+) 657 WP_000268644.1 CBS domain-containing protein -
  EL140_RS02905 (NCTC11427_00569) prfB 574627..575722 (+) 1096 WP_126475664.1 peptide chain release factor 2 -
  EL140_RS02910 (NCTC11427_00570) ftsE 575740..576432 (+) 693 WP_000022272.1 cell division ATP-binding protein FtsE -
  EL140_RS02915 (NCTC11427_00571) ftsX 576425..577351 (+) 927 WP_000625558.1 permease-like cell division protein FtsX -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21362.37 Da        Isoelectric Point: 4.4829

>NTDB_id=1121839 EL140_RS02855 WP_000613467.1 567837..568427(+) (clpP) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRKTLEQILADNSGK
SVEQIHADAERDYWMSAQETLEYGFIDEIMANNSLS

Nucleotide


Download         Length: 591 bp        

>NTDB_id=1121839 EL140_RS02855 WP_000613467.1 567837..568427(+) (clpP) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTATGATATTTACTCTCGTCTTCTGAAAGACCGCAT
CATCATGCTAACAGGTCCAGTTGAAGACAACATGGCCAACTCCGTTATTGCTCAGTTGCTCTTCTTGGATGCCCAAGACA
GCACAAAAGATATTTACCTTTATGTCAATACACCTGGAGGCTCTGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATCAAAGCGGATGTCCAAACAATCGTTATGGGGATGGCTGCATCCATGGGTACTGTCATCGCATCAAGTGGTGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCAGAGTATATGATTCACCAACCAATGGGTGGTACAGGTGGTGGTACCCAACAGA
CAGATATGGCAATCGCTGCAGAGCACTTGCTCAAAACTCGTAAGACTTTGGAGCAAATCCTTGCAGATAACTCTGGTAAA
TCAGTCGAGCAAATTCATGCAGATGCAGAACGTGATTACTGGATGAGTGCCCAAGAAACACTTGAATATGGCTTTATCGA
TGAAATCATGGCCAATAATTCGTTAAGCTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

95.408

100

0.954
  clpP Streptococcus pneumoniae R6

95.408

100

0.954
  clpP Streptococcus pneumoniae TIGR4

95.408

100

0.954
  clpP Streptococcus pneumoniae D39

95.408

100

0.954
  clpP Streptococcus pyogenes JRS4

92.308

99.49

0.918
  clpP Streptococcus pyogenes MGAS315

92.308

99.49

0.918
  clpP Streptococcus thermophilus LMD-9

91.282

99.49

0.908
  clpP Streptococcus thermophilus LMG 18311

91.282

99.49

0.908
  clpP Streptococcus mutans UA159

88.718

99.49

0.883
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

87.692

99.49

0.872
  clpP Lactococcus lactis subsp. cremoris KW2

87.179

99.49

0.867
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.031

98.469

0.571
  clpP Bacillus subtilis subsp. subtilis str. 168

57.292

97.959

0.561

Multiple sequence alignment