Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   EL140_RS00205 Genome accession   NZ_LR134336
Coordinates   35226..36575 (+) Length   449 a.a.
NCBI ID   WP_000801576.1    Uniprot ID   -
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 30226..41575
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS00170 (NCTC11427_00033) plsX 30379..31371 (+) 993 WP_000717449.1 phosphate acyltransferase PlsX -
  EL140_RS00175 (NCTC11427_00034) - 31377..31613 (+) 237 WP_000136451.1 acyl carrier protein -
  EL140_RS00180 (NCTC11427_00035) - 32054..32242 (+) 189 WP_000180830.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  EL140_RS00185 (NCTC11427_00036) - 32260..32427 (+) 168 WP_000415691.1 bacteriocin -
  EL140_RS00190 (NCTC11427_00037) - 32437..32625 (+) 189 WP_000722235.1 hypothetical protein -
  EL140_RS00200 (NCTC11427_00038) comA 33060..35213 (+) 2154 WP_000672141.1 peptide cleavage/export ABC transporter ComA Regulator
  EL140_RS00205 (NCTC11427_00039) comB 35226..36575 (+) 1350 WP_000801576.1 competence pheromone export protein ComB Regulator
  EL140_RS00210 (NCTC11427_00040) purC 36743..37450 (+) 708 WP_000043288.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  EL140_RS00215 (NCTC11427_00041) - 37507..41232 (+) 3726 WP_000361223.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49932.77 Da        Isoelectric Point: 5.0481

>NTDB_id=1121811 EL140_RS00205 WP_000801576.1 35226..36575(+) (comB) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MKPEFLESAEFYHRRYHNFSSRVILPMSLMLVFLFGFAVFAEKEISLSTRATVEPSRIIANIQSTSNQRIVANYLEENKL
VKQGDLLVEYQQGAEAVQAEAYASQLEMLKDQKKQLGYLQSSLKEGSDQFPEADKFGYQEMFRDYLSQASSLRSNVSQQN
ASISSQNAAASQSQAEIGNLISQTEDKIRDYKTAKSAIEKGDQLDSQNAAYSFYQTYKNQAGDDSQAKSQVIAQVDAQIA
QLESSLATYRVQYAGSGAQQAYATGLDSQLESLKSQHLVKVGQELTLLDQKILEAESGKKVQGGLLDKGKIIASEDGVLH
LNPETSESTMVAEGTLLAQLYPSLEKEGKTKLTAYLSSKDVARVKIGDSVRYTTTNDAKNQIFLDSTITSIDATATKTEK
GNFFKIEAETSLTPEQAESLRYGSEGRLTLITGKKSYLRYYWDQFLNRE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=1121811 EL140_RS00205 WP_000801576.1 35226..36575(+) (comB) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTACCATCGTCGTTACCATAATTTTTCCAGTCGGGTGATTTTACCTAT
GTCGCTTATGCTCGTGTTTCTGTTTGGATTTGCAGTCTTTGCTGAGAAAGAGATTAGTTTGTCTACTAGAGCTACTGTCG
AACCTAGTCGGATCATTGCCAACATCCAGTCGACTAGCAATCAACGGATTGTGGCAAATTATCTGGAAGAAAATAAACTG
GTCAAGCAGGGGGATTTACTCGTTGAGTACCAGCAGGGGGCGGAAGCTGTTCAAGCTGAAGCATACGCCAGTCAATTGGA
GATGTTAAAGGATCAAAAAAAGCAGTTGGGTTATTTGCAATCCAGTTTGAAAGAGGGGAGTGATCAATTTCCAGAGGCGG
ATAAGTTTGGATATCAGGAGATGTTTCGAGACTATCTCAGCCAAGCTAGTAGTCTTAGGAGCAATGTTTCTCAACAAAAT
GCCAGCATCTCTTCTCAAAATGCAGCCGCAAGTCAGAGTCAGGCTGAGATTGGCAACCTTATCAGCCAAACAGAGGATAA
AATCCGAGATTACAAAACAGCTAAGTCGGCGATTGAAAAAGGAGATCAACTGGATAGTCAAAATGCAGCCTACTCATTTT
ATCAGACTTATAAAAACCAAGCTGGAGATGATTCGCAAGCTAAATCGCAAGTTATTGCACAGGTGGATGCACAAATTGCC
CAGCTAGAGTCTAGTTTAGCTACTTATCGTGTGCAGTATGCGGGTTCTGGAGCTCAACAAGCCTACGCAACGGGACTGGA
TAGTCAACTGGAATCCCTCAAGTCTCAGCACCTAGTCAAAGTCGGCCAGGAATTAACCCTTTTGGATCAGAAAATTTTGG
AGGCAGAGTCGGGTAAGAAAGTCCAAGGAGGTCTGCTGGACAAGGGGAAAATTATAGCAAGTGAGGATGGGGTGCTTCAC
CTTAATCCTGAGACCAGTGAATCTACGATGGTTGCAGAAGGAACTCTGCTAGCCCAGCTCTATCCATCCTTGGAAAAAGA
AGGCAAAACCAAACTCACAGCCTATCTCAGTTCAAAAGATGTTGCTAGAGTTAAGATTGGGGACTCTGTCCGTTATACTA
CGACTAATGATGCGAAGAATCAAATCTTCCTGGATTCTACGATTACAAGTATTGATGCGACAGCTACCAAGACTGAAAAG
GGCAATTTCTTTAAAATAGAGGCGGAGACCAGTCTGACTCCTGAACAGGCAGAAAGTCTTCGCTATGGTTCAGAAGGGCG
TTTGACGCTAATCACAGGGAAGAAAAGCTATTTGCGCTATTATTGGGATCAATTTTTGAACAGAGAATAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mitis SK321

81.96

100

0.82
  comB Streptococcus pneumoniae Rx1

81.069

100

0.811
  comB Streptococcus pneumoniae D39

81.069

100

0.811
  comB Streptococcus pneumoniae R6

81.069

100

0.811
  comB Streptococcus pneumoniae TIGR4

80.624

100

0.806
  comB Streptococcus mitis NCTC 12261

79.955

100

0.8
  comB Streptococcus gordonii str. Challis substr. CH1

54.667

100

0.548

Multiple sequence alignment