Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   EL140_RS00200 Genome accession   NZ_LR134336
Coordinates   33060..35213 (+) Length   717 a.a.
NCBI ID   WP_000672141.1    Uniprot ID   -
Organism   Streptococcus oralis ATCC 35037 strain NCTC 11427     
Function   processing and transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 28060..40213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL140_RS00160 (NCTC11427_00031) - 28446..29615 (+) 1170 WP_000366327.1 pyridoxal phosphate-dependent aminotransferase -
  EL140_RS00165 (NCTC11427_00032) recO 29612..30382 (+) 771 WP_000616141.1 DNA repair protein RecO -
  EL140_RS00170 (NCTC11427_00033) plsX 30379..31371 (+) 993 WP_000717449.1 phosphate acyltransferase PlsX -
  EL140_RS00175 (NCTC11427_00034) - 31377..31613 (+) 237 WP_000136451.1 acyl carrier protein -
  EL140_RS00180 (NCTC11427_00035) - 32054..32242 (+) 189 WP_000180830.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  EL140_RS00185 (NCTC11427_00036) - 32260..32427 (+) 168 WP_000415691.1 bacteriocin -
  EL140_RS00190 (NCTC11427_00037) - 32437..32625 (+) 189 WP_000722235.1 hypothetical protein -
  EL140_RS00200 (NCTC11427_00038) comA 33060..35213 (+) 2154 WP_000672141.1 peptide cleavage/export ABC transporter ComA Regulator
  EL140_RS00205 (NCTC11427_00039) comB 35226..36575 (+) 1350 WP_000801576.1 competence pheromone export protein ComB Regulator
  EL140_RS00210 (NCTC11427_00040) purC 36743..37450 (+) 708 WP_000043288.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -

Sequence

Protein


Download         Length: 717 a.a.        Molecular weight: 80548.90 Da        Isoelectric Point: 6.9838

>NTDB_id=1121810 EL140_RS00200 WP_000672141.1 33060..35213(+) (comA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
MKFRKRHYRPQVDQMDCGVASLAMVFGYYGSYYSLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVIGQDKKHIHIADPDPGVKLTKISRERFAQEWTGVSLFMAPSPDYKPHKEKKQGLLSFLPI
LLKQRGLITNIVLATLLVTLINIVGSYYLQSIIDSYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLILGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTILIISLVLFSQNMTLFFISLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESSRYQKIDKEFVAYLKKSFTYSRAESQQKALKKVAQL
LLNVAVLWLGAILVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEQKTVEDLSMM
KGDMIFKQVHYKYGYGRDVLSDINLTIPQGSKMAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGNHADLLARGEFYAHLVNS

Nucleotide


Download         Length: 2154 bp        

>NTDB_id=1121810 EL140_RS00200 WP_000672141.1 33060..35213(+) (comA) [Streptococcus oralis ATCC 35037 strain NCTC 11427]
ATGAAATTTAGGAAAAGGCACTATCGTCCCCAGGTGGATCAGATGGATTGTGGCGTGGCTTCTTTGGCTATGGTCTTTGG
TTACTACGGTAGTTATTACTCCTTGGCTCATCTACGAGAGTTAGCCAAGACGACCATGGATGGGACGACCGCTTTGGGAC
TTGTAAAGGTGGCAGAGGAGATTGGATTTGAGACGCGGGCTATCAAGGCGGATATGACGCTCTTTGATTTGCCAGATTTG
ACCTTTCCTTTTGTGGCTCATGTGCTCAAGGAAGGGAAGTTGCTCCACTACTATGTGGTGATAGGTCAGGATAAAAAGCA
TATTCATATCGCTGATCCGGATCCTGGTGTCAAGCTGACCAAGATTTCCCGTGAGCGATTTGCGCAAGAATGGACAGGAG
TCAGTCTCTTTATGGCTCCGTCTCCAGACTATAAACCCCATAAGGAGAAAAAACAGGGGCTCCTATCCTTCTTGCCAATT
TTGCTCAAACAGCGGGGCTTGATTACCAATATCGTCCTAGCGACACTCTTGGTGACCTTGATCAATATCGTGGGTTCCTA
CTATCTTCAGTCCATCATTGATAGTTACGTACCAGACCAGATGCGCTCGACACTGGGCATCATCTCTATTGGGCTGGTCA
TCGTCTATATCCTCCAGCAGATTTTGTCTTATGCCCAGGAATATCTCCTACTGATACTTGGGCAACGCTTATCGATTGAC
GTGATTTTGTCCTACATCAAGCATGTTTTTCACCTGCCAATGTCCTTTTTTGCGACACGCAGGACAGGAGAAATCGTGTC
TCGTTTTACAGATGCCAATAGTATCATCGATGCGCTGGCGTCGACCATTCTGTCGATTTTCCTAGATGTGTCGACGATTT
TGATTATCTCGCTGGTCTTGTTTTCACAAAATATGACGCTCTTTTTCATTAGTCTACTTGCGCTTCCCATCTATACAGTG
ATTATCTTTGCCTTTATGAAGCCGTTTGAAAAGATGAATCGGGATACCATGGAAGCCAATGCGGTTCTGTCTTCCTCTAT
CATCGAGGACATCAACGGTATTGAGACCATTAAGTCTTTGACCAGTGAAAGTTCGCGCTATCAAAAGATTGACAAGGAAT
TTGTAGCTTATCTGAAAAAATCCTTTACCTATAGTCGGGCAGAAAGCCAGCAAAAGGCTCTGAAAAAAGTTGCCCAGCTC
CTGCTCAATGTTGCCGTTCTCTGGCTAGGAGCCATTCTTGTTATGGACGGGAAAATGAGTTTGGGCCAGCTGATTACCTA
TAATACTTTGCTTGTTTACTTTACCAATCCTTTGGAAAATATCATTAACCTACAAACCAAACTTCAGACAGCGCAGGTTG
CCAATAATCGCTTAAATGAGGTTTATCTAGTAGCTTCGGAGTTTGAGGAGCAGAAAACAGTCGAAGATTTGAGCATGATG
AAAGGGGATATGATCTTTAAACAAGTTCACTATAAGTATGGCTATGGGCGTGATGTCTTATCGGATATCAATTTGACCAT
TCCACAAGGGTCTAAGATGGCTTTTGTGGGGATTTCAGGTTCGGGTAAGACCACCTTAGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAGGGAGAGATTAGTCTGGGTGGTGTCAATCTTAATCAGATTGATAAAAAGGCCCTGCGCCAGTATATC
AACTACCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTCCTTGGAGCCAAGGAGGGGACGAC
TCAGGAAGATATCTTACGAGCAGTCGAGTTGGCAGAGATTCGGGAGGATATTGAGCGCATGCCTCTGAATTATCAGACAG
AATTGACTTCGGATGGGGCTGGAATTTCTGGTGGGCAACGGCAGAGAATCGCTCTGGCGCGTGCTCTCTTGACGGATGCA
CCTGTCTTGATCTTGGACGAGGCGACTAGCAGTTTGGATATTTTGACAGAGAAGCGGATCGTGGATAATCTCATGGCTTT
AGATAAGACCTTGATTTTCATCGCCCACCGCTTGACCATTGCTGAGCGAACAGAGAAGGTTGTTGTCTTGGATCAGGGCA
AGATTGTCGAAGAAGGCAACCATGCAGACTTGCTTGCCCGAGGTGAATTTTACGCCCATTTGGTCAATAGCTAG

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(500-650)

ABC transporter transmembrane region (ABC_membrane)

(170-438)

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Streptococcus mitis NCTC 12261

94.84

100

0.948
  comA Streptococcus pneumoniae Rx1

94.421

100

0.944
  comA Streptococcus pneumoniae D39

94.421

100

0.944
  comA Streptococcus pneumoniae R6

94.421

100

0.944
  comA Streptococcus mitis SK321

94.142

100

0.941
  comA Streptococcus pneumoniae TIGR4

94.003

100

0.94
  comA Streptococcus gordonii str. Challis substr. CH1

80.474

100

0.805
  comA/nlmT Streptococcus mutans UA159

64.296

100

0.643

Multiple sequence alignment