Detailed information NTG1121534

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: EL133_RS05415
• Genome accession: NZ_LR134323
• Coordinates: 1047320..1048162 (-)
• Length: 280 a.a.
• NCBI ID: WP_006740428.1
• Uniprot ID: G5KFZ9
• Organism: Streptococcus urinalis strain NCTC13766
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1042320..1053162

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL133_RS05395 (NCTC13766_01118)	-	1042757..1043641 (+)	885	WP_006740070.1	LysR family transcriptional regulator	-
EL133_RS05400 (NCTC13766_01119)	-	1043650..1044965 (-)	1316	Protein_1053	serine hydrolase	-
EL133_RS05410 (NCTC13766_01121)	topA	1045089..1047221 (-)	2133	WP_006738721.1	type I DNA topoisomerase	-
EL133_RS05415 (NCTC13766_01122)	dprA	1047320..1048162 (-)	843	WP_006740428.1	DNA-processing protein DprA	Machinery gene
EL133_RS05420 (NCTC13766_01123)	-	1048221..1048772 (-)	552	WP_006739988.1	sugar O-acetyltransferase	-
EL133_RS05425 (NCTC13766_01124)	-	1048781..1049563 (-)	783	WP_006740161.1	ribonuclease HII	-
EL133_RS05430 (NCTC13766_01125)	ylqF	1049550..1050407 (-)	858	WP_006738547.1	ribosome biogenesis GTPase YlqF	-
EL133_RS05435 (NCTC13766_01126)	-	1050498..1052011 (-)	1514	Protein_1059	tyrosine-type recombinase/integrase	-
EL133_RS05440 (NCTC13766_01127)	-	1052086..1052319 (-)	234	WP_000693749.1	hypothetical protein	-
EL133_RS05445 (NCTC13766_01128)	-	1052588..1052809 (-)	222	WP_006739042.1	helix-turn-helix domain-containing protein	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31277.09 Da
• Isoelectric Point: 8.7629

>NTDB_id=1121534 EL133_RS05415 WP_006740428.1 1047320..1048162(-) (dprA) [Streptococcus urinalis strain NCTC13766]
MNNFELYKLKKSGLANKAILNVLSYQEKNQKSLSIRDIAVVSQTKDPVSFIENYKKIDSKELRKEFLKFPSFSILDSIYP
ESLKQIYNPPVLLFYQGNLDILELPKIAVVGSRDCSQEGTKVLEKIIKELGNQYIIVSGLARGIDTSAHMSSLKFGGSTI
AVIGNGLDYFYPKENKVLQNYLSKNHLVLSEYGPNQSPLKFHFPERNRIIAGLSKGILIIEAKLRSGSLITCERGLEEGR
DIFAVPGSTLSGYSEGCHQLIKEGAYCVTSGQDILLHYQC

Nucleotide

• Length: 843 bp

>NTDB_id=1121534 EL133_RS05415 WP_006740428.1 1047320..1048162(-) (dprA) [Streptococcus urinalis strain NCTC13766]
ATGAATAACTTTGAATTATATAAATTAAAAAAATCAGGTTTAGCAAACAAAGCTATTTTAAATGTATTGTCATATCAAGA
GAAAAATCAAAAATCACTATCAATTCGTGATATAGCGGTAGTTTCACAAACTAAAGATCCAGTTTCTTTTATAGAAAATT
ATAAGAAAATTGATTCAAAAGAATTACGAAAAGAATTTTTAAAATTTCCTAGTTTTTCTATTTTAGATTCTATTTATCCT
GAGTCTTTAAAGCAAATTTATAATCCACCTGTGTTACTTTTTTATCAGGGAAATCTTGATATTTTAGAACTTCCTAAAAT
AGCCGTCGTCGGCTCTCGTGATTGTAGTCAAGAAGGAACAAAAGTATTAGAGAAAATCATAAAGGAATTGGGAAATCAAT
ATATTATAGTTTCTGGTCTTGCTAGAGGGATAGATACATCAGCTCATATGTCTTCTTTAAAATTTGGAGGTTCAACTATA
GCTGTTATTGGAAATGGTTTAGATTATTTTTATCCCAAAGAAAATAAAGTTTTACAAAATTATTTGTCAAAAAATCATTT
AGTGTTAAGTGAATACGGTCCTAACCAATCACCATTAAAATTCCATTTTCCTGAAAGGAATCGTATTATTGCAGGTTTAT
CAAAAGGAATTTTAATAATAGAAGCAAAATTAAGATCTGGAAGTTTGATTACTTGCGAAAGAGGATTAGAAGAAGGAAGA
GATATTTTTGCTGTACCAGGATCCACACTATCAGGTTATTCAGAGGGTTGTCATCAGTTGATCAAAGAAGGTGCTTATTG
CGTTACAAGCGGTCAAGATATATTATTACATTATCAGTGCTGA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (74-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

3D structure

• AlphaFold DB: G5KFZ9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.545	98.214	0.654
dprA/cilB/dalA	Streptococcus mitis SK321	62.724	99.643	0.625
dprA/cilB/dalA	Streptococcus pneumoniae D39	62.366	99.643	0.621
dprA/cilB/dalA	Streptococcus pneumoniae R6	62.366	99.643	0.621
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	62.366	99.643	0.621
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	62.366	99.643	0.621
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	62.007	99.643	0.618
dprA	Lactococcus lactis subsp. cremoris KW2	56.115	99.286	0.557
dprA	Haemophilus influenzae Rd KW20	39.015	94.286	0.368
dprA	Glaesserella parasuis strain SC1401	45.175	81.429	0.368