Detailed information
Bioinformatically predicted
Overview
| Name | prx | Type | Regulator |
| Locus tag | EL136_RS04295 | Genome accession | NZ_LR134317 |
| Coordinates | 896267..896455 (-) | Length | 62 a.a. |
| NCBI ID | WP_037578450.1 | Uniprot ID | A0A922NVX2 |
| Organism | Streptococcus equi subsp. zooepidemicus strain NCTC6180 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 888696..935240 | 896267..896455 | within | 0 |
Gene organization within MGE regions
Location: 888696..935240
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EL136_RS04260 (NCTC6180_00875) | pfkA | 888696..889709 (-) | 1014 | WP_012515510.1 | 6-phosphofructokinase | - |
| EL136_RS04265 (NCTC6180_00876) | - | 889789..892899 (-) | 3111 | WP_154803882.1 | DNA polymerase III subunit alpha | - |
| EL136_RS04270 (NCTC6180_00877) | - | 893141..893512 (+) | 372 | WP_012515508.1 | GntR family transcriptional regulator | - |
| EL136_RS04275 (NCTC6180_00878) | - | 893512..894210 (+) | 699 | WP_012515507.1 | ABC transporter ATP-binding protein | - |
| EL136_RS04280 (NCTC6180_00879) | - | 894220..895014 (+) | 795 | WP_154803883.1 | ABC transporter permease | - |
| EL136_RS04285 (NCTC6180_00880) | - | 895061..895672 (-) | 612 | WP_154803884.1 | TVP38/TMEM64 family protein | - |
| EL136_RS04295 (NCTC6180_00882) | prx | 896267..896455 (-) | 189 | WP_037578450.1 | hypothetical protein | Regulator |
| EL136_RS04300 (NCTC6180_00883) | - | 896695..897846 (+) | 1152 | WP_037578452.1 | DNA/RNA non-specific endonuclease | - |
| EL136_RS04305 (NCTC6180_00884) | - | 897960..898823 (-) | 864 | WP_037578454.1 | hypothetical protein | - |
| EL136_RS04310 (NCTC6180_00885) | - | 898811..899335 (-) | 525 | WP_037578457.1 | Panacea domain-containing protein | - |
| EL136_RS04315 | - | 899411..900981 (+) | 1571 | WP_154803599.1 | IS3 family transposase | - |
| EL136_RS04320 (NCTC6180_00888) | - | 901173..901787 (-) | 615 | WP_154803885.1 | hypothetical protein | - |
| EL136_RS04325 (NCTC6180_00889) | - | 901789..902211 (-) | 423 | WP_232013953.1 | collagen-like protein | - |
| EL136_RS04330 (NCTC6180_00890) | - | 902221..902994 (-) | 774 | WP_138119235.1 | hypothetical protein | - |
| EL136_RS04335 (NCTC6180_00891) | - | 903005..903607 (-) | 603 | WP_154803886.1 | hypothetical protein | - |
| EL136_RS04340 (NCTC6180_00892) | - | 903619..904383 (-) | 765 | WP_154803887.1 | CHAP domain-containing protein | - |
| EL136_RS04345 (NCTC6180_00893) | - | 904385..904720 (-) | 336 | WP_154803888.1 | phage holin family protein | - |
| EL136_RS04350 (NCTC6180_00894) | - | 904722..905021 (-) | 300 | WP_154803889.1 | hypothetical protein | - |
| EL136_RS11265 (NCTC6180_00895) | - | 905034..905156 (-) | 123 | WP_269206307.1 | hypothetical protein | - |
| EL136_RS04355 (NCTC6180_00896) | - | 905170..905520 (-) | 351 | WP_154803890.1 | DUF1366 domain-containing protein | - |
| EL136_RS04360 (NCTC6180_00897) | - | 905531..907387 (-) | 1857 | WP_154803891.1 | DUF859 family phage minor structural protein | - |
| EL136_RS04365 (NCTC6180_00898) | - | 907392..910823 (-) | 3432 | WP_154803892.1 | phage tail protein | - |
| EL136_RS04370 (NCTC6180_00899) | - | 910824..912305 (-) | 1482 | WP_154803893.1 | distal tail protein Dit | - |
| EL136_RS04375 (NCTC6180_00900) | - | 912306..914111 (-) | 1806 | WP_154803894.1 | phage tail protein | - |
| EL136_RS04380 (NCTC6180_00901) | - | 914104..914562 (-) | 459 | WP_138119215.1 | hypothetical protein | - |
| EL136_RS04385 (NCTC6180_00902) | - | 914535..914852 (-) | 318 | WP_138119213.1 | hypothetical protein | - |
| EL136_RS04390 (NCTC6180_00903) | - | 914864..915370 (-) | 507 | WP_138119211.1 | phage major tail protein, TP901-1 family | - |
| EL136_RS04395 (NCTC6180_00904) | - | 915383..915793 (-) | 411 | WP_138119209.1 | DUF5072 family protein | - |
| EL136_RS04400 (NCTC6180_00905) | - | 915795..916190 (-) | 396 | WP_138119207.1 | hypothetical protein | - |
| EL136_RS04405 (NCTC6180_00906) | - | 916187..916498 (-) | 312 | WP_138119206.1 | hypothetical protein | - |
| EL136_RS04410 (NCTC6180_00907) | - | 916495..916839 (-) | 345 | WP_138119204.1 | phage head-tail connector protein | - |
| EL136_RS04415 (NCTC6180_00908) | - | 916853..917146 (-) | 294 | WP_138119202.1 | HeH/LEM domain-containing protein | - |
| EL136_RS04420 (NCTC6180_00909) | - | 917160..918050 (-) | 891 | WP_154803895.1 | phage capsid protein | - |
| EL136_RS04425 (NCTC6180_00910) | - | 918070..918639 (-) | 570 | WP_138119199.1 | DUF4355 domain-containing protein | - |
| EL136_RS04430 (NCTC6180_00912) | - | 918967..919875 (-) | 909 | WP_138119197.1 | minor capsid protein | - |
| EL136_RS04435 (NCTC6180_00913) | - | 919868..921169 (-) | 1302 | WP_138119195.1 | phage portal protein | - |
| EL136_RS04440 (NCTC6180_00914) | - | 921169..922443 (-) | 1275 | WP_138119193.1 | PBSX family phage terminase large subunit | - |
| EL136_RS04445 (NCTC6180_00915) | - | 922433..922771 (-) | 339 | WP_138119191.1 | phBC6A51 family helix-turn-helix protein | - |
| EL136_RS04450 (NCTC6180_00916) | - | 922844..923101 (-) | 258 | WP_138119189.1 | type II toxin-antitoxin system RelE family toxin | - |
| EL136_RS04455 (NCTC6180_00917) | relB | 923098..923331 (-) | 234 | WP_138119187.1 | type II toxin-antitoxin system RelB family antitoxin | - |
| EL136_RS04460 (NCTC6180_00918) | - | 923501..923938 (-) | 438 | WP_138119185.1 | DUF1492 domain-containing protein | - |
| EL136_RS04465 (NCTC6180_00919) | - | 924130..924465 (-) | 336 | WP_154803896.1 | hypothetical protein | - |
| EL136_RS11305 | - | 924440..924604 (-) | 165 | Protein_882 | DUF1642 domain-containing protein | - |
| EL136_RS11110 (NCTC6180_00920) | - | 924648..924842 (-) | 195 | WP_138119181.1 | hypothetical protein | - |
| EL136_RS04475 (NCTC6180_00921) | - | 924829..925341 (-) | 513 | WP_138119179.1 | crossover junction endodeoxyribonuclease RuvC | - |
| EL136_RS04480 (NCTC6180_00922) | - | 925338..925679 (-) | 342 | WP_003052428.1 | hypothetical protein | - |
| EL136_RS04485 (NCTC6180_00923) | - | 925857..926654 (-) | 798 | WP_154803897.1 | PD-(D/E)XK nuclease-like domain-containing protein | - |
| EL136_RS04490 (NCTC6180_00924) | - | 926651..927571 (-) | 921 | WP_154803898.1 | recombinase RecT | - |
| EL136_RS04495 (NCTC6180_00925) | - | 927627..927833 (-) | 207 | WP_154803899.1 | hypothetical protein | - |
| EL136_RS04500 (NCTC6180_00926) | - | 927870..928103 (-) | 234 | WP_154803900.1 | hypothetical protein | - |
| EL136_RS04505 (NCTC6180_00927) | - | 928084..928467 (-) | 384 | WP_154803901.1 | DnaD domain-containing protein | - |
| EL136_RS04510 | - | 928599..928844 (-) | 246 | WP_012678836.1 | helix-turn-helix domain-containing protein | - |
| EL136_RS10985 (NCTC6180_00929) | - | 929048..929188 (-) | 141 | WP_172954514.1 | hypothetical protein | - |
| EL136_RS04515 (NCTC6180_00930) | - | 929190..929480 (-) | 291 | WP_154803902.1 | MerR family transcriptional regulator | - |
| EL136_RS04520 (NCTC6180_00931) | - | 929669..929884 (+) | 216 | WP_027970312.1 | hypothetical protein | - |
| EL136_RS04525 (NCTC6180_00933) | - | 930039..930764 (-) | 726 | WP_154803903.1 | phage antirepressor KilAC domain-containing protein | - |
| EL136_RS04530 (NCTC6180_00934) | - | 930832..931023 (-) | 192 | WP_043983624.1 | helix-turn-helix transcriptional regulator | - |
| EL136_RS04535 (NCTC6180_00935) | - | 931117..931809 (+) | 693 | WP_136059166.1 | DUF4145 domain-containing protein | - |
| EL136_RS04540 (NCTC6180_00936) | - | 931785..931994 (-) | 210 | WP_136059167.1 | hypothetical protein | - |
| EL136_RS04545 (NCTC6180_00937) | - | 932028..932186 (-) | 159 | WP_154803904.1 | hypothetical protein | - |
| EL136_RS04550 (NCTC6180_00938) | - | 932348..933142 (+) | 795 | WP_154803905.1 | XRE family transcriptional regulator | - |
| EL136_RS04555 (NCTC6180_00939) | - | 933357..934031 (+) | 675 | WP_154803906.1 | NYN domain-containing protein | - |
| EL136_RS04560 (NCTC6180_00940) | - | 934152..935240 (+) | 1089 | WP_043052993.1 | site-specific integrase | - |
Sequence
Protein
Download Length: 62 a.a. Molecular weight: 7231.20 Da Isoelectric Point: 4.3297
>NTDB_id=1121271 EL136_RS04295 WP_037578450.1 896267..896455(-) (prx) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
MLTYDEFKQAIDDGYIAGDTVTIVRKNGQIFDYVLPGEPVRPWETLTEERVDEVLTKLHYIK
MLTYDEFKQAIDDGYIAGDTVTIVRKNGQIFDYVLPGEPVRPWETLTEERVDEVLTKLHYIK
Nucleotide
Download Length: 189 bp
>NTDB_id=1121271 EL136_RS04295 WP_037578450.1 896267..896455(-) (prx) [Streptococcus equi subsp. zooepidemicus strain NCTC6180]
ATGCTAACATACGACGAGTTTAAGCAAGCTATTGACGACGGTTATATCGCAGGCGACACAGTCACGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCTGGTGAGCCTGTGAGACCGTGGGAGACTCTGACTGAAGAAAGAGTAGACGAGG
TGCTGACGAAATTACACTATATCAAGTGA
ATGCTAACATACGACGAGTTTAAGCAAGCTATTGACGACGGTTATATCGCAGGCGACACAGTCACGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCTGGTGAGCCTGTGAGACCGTGGGAGACTCTGACTGAAGAAAGAGTAGACGAGG
TGCTGACGAAATTACACTATATCAAGTGA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS315 |
75.806 |
100 |
0.758 |
| prx | Streptococcus pyogenes MGAS315 |
75.862 |
93.548 |
0.71 |
| prx | Streptococcus pyogenes MGAS8232 |
74.138 |
93.548 |
0.694 |
| prx | Streptococcus pyogenes MGAS315 |
72.414 |
93.548 |
0.677 |
| prx | Streptococcus pyogenes MGAS315 |
69.492 |
95.161 |
0.661 |
| prx | Streptococcus pyogenes MGAS315 |
90.476 |
67.742 |
0.613 |
| prx | Streptococcus pyogenes MGAS315 |
78.049 |
66.129 |
0.516 |