Detailed information
Bioinformatically predicted
Overview
| Name | prx | Type | Regulator |
| Locus tag | EL139_RS04315 | Genome accession | NZ_LR134316 |
| Coordinates | 809981..810163 (+) | Length | 60 a.a. |
| NCBI ID | WP_111717696.1 | Uniprot ID | A0A9X8T223 |
| Organism | Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 764808..824792 | 809981..810163 | within | 0 |
Gene organization within MGE regions
Location: 764808..824792
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EL139_RS04040 (NCTC6181_00823) | - | 764808..765881 (-) | 1074 | WP_111717733.1 | site-specific integrase | - |
| EL139_RS04045 (NCTC6181_00824) | - | 766142..767734 (-) | 1593 | WP_111717732.1 | SIR2 family protein | - |
| EL139_RS04050 (NCTC6181_00825) | - | 767752..768138 (-) | 387 | WP_111705753.1 | ImmA/IrrE family metallo-endopeptidase | - |
| EL139_RS04055 (NCTC6181_00826) | - | 768142..768489 (-) | 348 | WP_111717731.1 | helix-turn-helix transcriptional regulator | - |
| EL139_RS04060 (NCTC6181_00827) | - | 769247..769438 (+) | 192 | WP_001283052.1 | hypothetical protein | - |
| EL139_RS04065 (NCTC6181_00828) | - | 769449..770249 (+) | 801 | WP_111717730.1 | phage antirepressor KilAC domain-containing protein | - |
| EL139_RS04070 (NCTC6181_00829) | - | 770310..770585 (+) | 276 | WP_003052448.1 | hypothetical protein | - |
| EL139_RS04075 (NCTC6181_00830) | - | 770582..770752 (+) | 171 | WP_111717729.1 | hypothetical protein | - |
| EL139_RS04080 (NCTC6181_00831) | - | 770745..770951 (+) | 207 | WP_050317062.1 | hypothetical protein | - |
| EL139_RS04085 (NCTC6181_00832) | - | 770948..771331 (+) | 384 | WP_111717728.1 | hypothetical protein | - |
| EL139_RS04090 (NCTC6181_00834) | - | 771477..771680 (+) | 204 | WP_002983407.1 | hypothetical protein | - |
| EL139_RS04095 (NCTC6181_00835) | - | 771768..772067 (+) | 300 | WP_043024982.1 | hypothetical protein | - |
| EL139_RS04100 (NCTC6181_00836) | - | 772067..773224 (+) | 1158 | WP_002983409.1 | DUF2800 domain-containing protein | - |
| EL139_RS04105 (NCTC6181_00837) | - | 773238..773801 (+) | 564 | WP_002983410.1 | DUF2815 family protein | - |
| EL139_RS04110 (NCTC6181_00838) | - | 773844..775766 (+) | 1923 | WP_111717727.1 | DNA polymerase | - |
| EL139_RS04115 (NCTC6181_00839) | - | 775771..778155 (+) | 2385 | WP_111717726.1 | phage/plasmid primase, P4 family | - |
| EL139_RS04120 (NCTC6181_00840) | - | 778522..778797 (+) | 276 | WP_111717725.1 | VRR-NUC domain-containing protein | - |
| EL139_RS04125 (NCTC6181_00841) | - | 778794..780116 (+) | 1323 | WP_002983414.1 | SNF2-related protein | - |
| EL139_RS11150 (NCTC6181_00842) | - | 780117..780284 (+) | 168 | WP_164714884.1 | hypothetical protein | - |
| EL139_RS04130 (NCTC6181_00843) | - | 780281..780547 (+) | 267 | WP_111717724.1 | hypothetical protein | - |
| EL139_RS04135 (NCTC6181_00844) | - | 780551..780742 (+) | 192 | WP_111717723.1 | hypothetical protein | - |
| EL139_RS04140 (NCTC6181_00845) | - | 780739..781155 (+) | 417 | WP_002988747.1 | DUF722 domain-containing protein | - |
| EL139_RS04145 (NCTC6181_00846) | terS | 781275..781970 (+) | 696 | WP_050318691.1 | phage terminase small subunit | - |
| EL139_RS04150 (NCTC6181_00847) | - | 781963..783258 (+) | 1296 | WP_164714885.1 | PBSX family phage terminase large subunit | - |
| EL139_RS04155 (NCTC6181_00848) | - | 783272..784774 (+) | 1503 | WP_111717722.1 | phage portal protein | - |
| EL139_RS04160 (NCTC6181_00849) | - | 784779..786272 (+) | 1494 | WP_111717721.1 | phage minor capsid protein | - |
| EL139_RS04165 (NCTC6181_00850) | - | 786272..786499 (+) | 228 | WP_111717720.1 | hypothetical protein | - |
| EL139_RS04170 (NCTC6181_00851) | - | 786655..787599 (+) | 945 | WP_111715146.1 | IS30 family transposase | - |
| EL139_RS04175 (NCTC6181_00852) | - | 787637..787903 (+) | 267 | WP_111717719.1 | hypothetical protein | - |
| EL139_RS04180 (NCTC6181_00853) | - | 788033..788647 (+) | 615 | WP_111717718.1 | hypothetical protein | - |
| EL139_RS04185 (NCTC6181_00854) | - | 788651..789487 (+) | 837 | WP_111717717.1 | N4-gp56 family major capsid protein | - |
| EL139_RS04190 (NCTC6181_00855) | - | 789497..789766 (+) | 270 | WP_111717716.1 | HeH/LEM domain-containing protein | - |
| EL139_RS04195 (NCTC6181_00856) | - | 789792..790193 (+) | 402 | WP_164714920.1 | hypothetical protein | - |
| EL139_RS04200 (NCTC6181_00857) | - | 790183..790515 (+) | 333 | WP_111717714.1 | minor capsid protein | - |
| EL139_RS04205 (NCTC6181_00858) | - | 790515..790871 (+) | 357 | WP_111717713.1 | minor capsid protein | - |
| EL139_RS04210 (NCTC6181_00859) | - | 790868..791266 (+) | 399 | WP_111717712.1 | minor capsid protein | - |
| EL139_RS04215 (NCTC6181_00860) | - | 791266..791754 (+) | 489 | WP_111717711.1 | phage tail protein | - |
| EL139_RS04220 (NCTC6181_00861) | - | 791797..792231 (+) | 435 | WP_111717710.1 | hypothetical protein | - |
| EL139_RS04225 (NCTC6181_00862) | - | 792235..792816 (+) | 582 | WP_111717709.1 | bacteriophage Gp15 family protein | - |
| EL139_RS04230 (NCTC6181_00863) | - | 792806..796066 (+) | 3261 | WP_111717708.1 | tape measure protein | - |
| EL139_RS04235 (NCTC6181_00864) | - | 796063..796779 (+) | 717 | WP_111717707.1 | distal tail protein Dit | - |
| EL139_RS04240 (NCTC6181_00865) | - | 796776..798923 (+) | 2148 | WP_111717706.1 | phage tail spike protein | - |
| EL139_RS04245 (NCTC6181_00866) | - | 798920..800317 (+) | 1398 | WP_111717705.1 | hypothetical protein | - |
| EL139_RS04250 (NCTC6181_00867) | - | 800320..800943 (+) | 624 | WP_111717704.1 | hypothetical protein | - |
| EL139_RS04255 (NCTC6181_00868) | - | 800954..802840 (+) | 1887 | WP_111717703.1 | gp58-like family protein | - |
| EL139_RS04260 (NCTC6181_00869) | - | 802852..803280 (+) | 429 | WP_111717702.1 | DUF1617 family protein | - |
| EL139_RS04265 (NCTC6181_00870) | - | 803283..803903 (+) | 621 | WP_111717701.1 | DUF1366 domain-containing protein | - |
| EL139_RS04270 (NCTC6181_00871) | - | 803914..804213 (+) | 300 | WP_002988799.1 | hypothetical protein | - |
| EL139_RS04275 (NCTC6181_00872) | - | 804210..804395 (+) | 186 | WP_011888776.1 | holin | - |
| EL139_RS04280 (NCTC6181_00874) | - | 804509..805726 (+) | 1218 | WP_111717700.1 | peptidoglycan amidohydrolase family protein | - |
| EL139_RS04285 (NCTC6181_00875) | - | 806032..807003 (+) | 972 | WP_011888780.1 | Abi family protein | - |
| EL139_RS04290 (NCTC6181_00876) | - | 807126..808259 (+) | 1134 | WP_111714946.1 | ISAs1 family transposase | - |
| EL139_RS04295 (NCTC6181_00878) | - | 808513..808713 (+) | 201 | WP_011888781.1 | CsbD family protein | - |
| EL139_RS04300 (NCTC6181_00879) | - | 808811..808996 (-) | 186 | WP_111717699.1 | XRE family transcriptional regulator | - |
| EL139_RS04305 (NCTC6181_00880) | - | 808998..809471 (-) | 474 | WP_111717698.1 | hypothetical protein | - |
| EL139_RS04310 (NCTC6181_00881) | - | 809503..809811 (-) | 309 | WP_111717697.1 | hypothetical protein | - |
| EL139_RS04315 (NCTC6181_00882) | prx | 809981..810163 (+) | 183 | WP_111717696.1 | Paratox | Regulator |
| EL139_RS04320 (NCTC6181_00883) | - | 810394..811014 (-) | 621 | WP_111717695.1 | alpha/beta hydrolase | - |
| EL139_RS04325 (NCTC6181_00884) | - | 811027..811635 (-) | 609 | WP_111717694.1 | flavin reductase family protein | - |
| EL139_RS04330 (NCTC6181_00885) | - | 811811..812272 (-) | 462 | WP_231871986.1 | VOC family protein | - |
| EL139_RS04335 (NCTC6181_00886) | - | 812405..814462 (-) | 2058 | WP_111717693.1 | sodium:proton antiporter | - |
| EL139_RS04340 (NCTC6181_00887) | - | 814474..814734 (-) | 261 | WP_111717692.1 | hypothetical protein | - |
| EL139_RS04345 (NCTC6181_00888) | - | 814722..815306 (-) | 585 | WP_111717691.1 | GNAT family N-acetyltransferase | - |
| EL139_RS04350 (NCTC6181_00889) | - | 815608..815886 (-) | 279 | WP_111717690.1 | GNAT family N-acetyltransferase | - |
| EL139_RS04355 (NCTC6181_00890) | - | 816002..816403 (-) | 402 | WP_126442244.1 | GNAT family N-acetyltransferase | - |
| EL139_RS04360 (NCTC6181_00891) | - | 816397..817338 (-) | 942 | WP_111717688.1 | 2-keto-3-deoxygluconate permease | - |
| EL139_RS04365 (NCTC6181_00892) | - | 817387..817842 (-) | 456 | WP_111717687.1 | MarR family transcriptional regulator | - |
| EL139_RS04370 (NCTC6181_00893) | - | 817974..818948 (-) | 975 | WP_111717686.1 | amidohydrolase family protein | - |
| EL139_RS04375 | - | 819359..819562 (+) | 204 | WP_003053018.1 | cold-shock protein | - |
| EL139_RS04380 (NCTC6181_00895) | - | 819758..820219 (+) | 462 | WP_003054759.1 | CtsR family transcriptional regulator | - |
| EL139_RS04385 (NCTC6181_00896) | clpC | 820219..822663 (+) | 2445 | WP_111717685.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| EL139_RS04390 (NCTC6181_00897) | groES | 822841..823131 (+) | 291 | WP_111717684.1 | co-chaperone GroES | - |
| EL139_RS04395 (NCTC6181_00898) | groL | 823167..824792 (+) | 1626 | WP_012767614.1 | chaperonin GroEL | - |
Sequence
Protein
Download Length: 60 a.a. Molecular weight: 6918.75 Da Isoelectric Point: 3.9944
>NTDB_id=1121219 EL139_RS04315 WP_111717696.1 809981..810163(+) (prx) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
MLTYDEFKQAIDDGYIAGDTVTIVRKNGQIFDYVLPGEPVRQWEVVTEEVVGEVTRELER
MLTYDEFKQAIDDGYIAGDTVTIVRKNGQIFDYVLPGEPVRQWEVVTEEVVGEVTRELER
Nucleotide
Download Length: 183 bp
>NTDB_id=1121219 EL139_RS04315 WP_111717696.1 809981..810163(+) (prx) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC6181]
ATGCTAACATACGACGAATTTAAGCAAGCGATTGATGACGGATATATCGCAGGAGACACAGTCACGATTGTGCGCAAAAA
CGGACAGATTTTTGATTATGTGTTGCCTGGTGAGCCTGTGAGACAGTGGGAAGTAGTGACGGAGGAAGTGGTGGGAGAAG
TGACGAGAGAGTTAGAACGCTAG
ATGCTAACATACGACGAATTTAAGCAAGCGATTGATGACGGATATATCGCAGGAGACACAGTCACGATTGTGCGCAAAAA
CGGACAGATTTTTGATTATGTGTTGCCTGGTGAGCCTGTGAGACAGTGGGAAGTAGTGACGGAGGAAGTGGTGGGAGAAG
TGACGAGAGAGTTAGAACGCTAG
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS315 |
78.333 |
100 |
0.783 |
| prx | Streptococcus pyogenes MGAS8232 |
76.667 |
100 |
0.767 |
| prx | Streptococcus pyogenes MGAS315 |
71.667 |
100 |
0.717 |
| prx | Streptococcus pyogenes MGAS315 |
71.667 |
100 |
0.717 |
| prx | Streptococcus pyogenes MGAS315 |
90.244 |
68.333 |
0.617 |
| prx | Streptococcus pyogenes MGAS315 |
85.714 |
70 |
0.6 |
| prx | Streptococcus pyogenes MGAS315 |
78.049 |
68.333 |
0.533 |