Detailed information
Bioinformatically predicted
Overview
| Name | prx | Type | Regulator |
| Locus tag | EL107_RS03490 | Genome accession | NZ_LR134314 |
| Coordinates | 706364..706546 (-) | Length | 60 a.a. |
| NCBI ID | WP_011018104.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain NCTC8302 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 706364..757507 | 706364..706546 | within | 0 |
Gene organization within MGE regions
Location: 706364..757507
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EL107_RS03490 (NCTC8302_00702) | prx | 706364..706546 (-) | 183 | WP_011018104.1 | hypothetical protein | Regulator |
| EL107_RS03495 (NCTC8302_00703) | sda | 706786..707784 (+) | 999 | WP_032463908.1 | streptodornase A | - |
| EL107_RS03500 (NCTC8302_00704) | - | 707925..708518 (-) | 594 | WP_003051628.1 | GNAT family N-acetyltransferase | - |
| EL107_RS03505 (NCTC8302_00705) | - | 708518..708682 (-) | 165 | WP_021340366.1 | hypothetical protein | - |
| EL107_RS03510 (NCTC8302_00706) | - | 708831..710036 (-) | 1206 | WP_023078214.1 | glucosaminidase domain-containing protein | - |
| EL107_RS09655 (NCTC8302_00707) | - | 710024..710146 (-) | 123 | WP_021775315.1 | hypothetical protein | - |
| EL107_RS03515 (NCTC8302_00708) | - | 710149..710334 (-) | 186 | WP_011184796.1 | holin | - |
| EL107_RS03520 (NCTC8302_00709) | - | 710331..710630 (-) | 300 | WP_011184797.1 | hypothetical protein | - |
| EL107_RS03525 (NCTC8302_00710) | - | 710641..711258 (-) | 618 | WP_011018111.1 | DUF1366 domain-containing protein | - |
| EL107_RS03530 (NCTC8302_00711) | - | 711261..711689 (-) | 429 | WP_011184798.1 | DUF1617 family protein | - |
| EL107_RS03535 (NCTC8302_00712) | - | 711701..713716 (-) | 2016 | WP_011184799.1 | gp58-like family protein | - |
| EL107_RS03540 (NCTC8302_00713) | - | 713731..714843 (-) | 1113 | WP_011184800.1 | hyaluronoglucosaminidase | - |
| EL107_RS03545 (NCTC8302_00714) | - | 714843..716990 (-) | 2148 | WP_023078210.1 | phage tail spike protein | - |
| EL107_RS03550 (NCTC8302_00715) | - | 716987..717703 (-) | 717 | WP_011018116.1 | distal tail protein Dit | - |
| EL107_RS03555 (NCTC8302_00716) | - | 717700..720960 (-) | 3261 | WP_047149499.1 | tape measure protein | - |
| EL107_RS03560 (NCTC8302_00717) | - | 720950..721531 (-) | 582 | WP_011018118.1 | bacteriophage Gp15 family protein | - |
| EL107_RS03565 (NCTC8302_00718) | - | 721535..721969 (-) | 435 | WP_011018119.1 | hypothetical protein | - |
| EL107_RS03570 (NCTC8302_00719) | - | 722013..722474 (-) | 462 | WP_011018120.1 | phage tail tube protein | - |
| EL107_RS03575 (NCTC8302_00720) | - | 722474..722872 (-) | 399 | WP_011018121.1 | minor capsid protein | - |
| EL107_RS03580 (NCTC8302_00721) | - | 722869..723225 (-) | 357 | WP_010922083.1 | minor capsid protein | - |
| EL107_RS03585 (NCTC8302_00722) | - | 723225..723557 (-) | 333 | WP_010922082.1 | minor capsid protein | - |
| EL107_RS03590 (NCTC8302_00723) | - | 723547..723963 (-) | 417 | WP_011018123.1 | hypothetical protein | - |
| EL107_RS03595 (NCTC8302_00724) | - | 724017..724835 (-) | 819 | WP_010922080.1 | N4-gp56 family major capsid protein | - |
| EL107_RS03600 (NCTC8302_00725) | - | 724839..725453 (-) | 615 | WP_010922079.1 | hypothetical protein | - |
| EL107_RS03605 (NCTC8302_00726) | - | 725579..725845 (-) | 267 | WP_010922078.1 | hypothetical protein | - |
| EL107_RS03610 (NCTC8302_00727) | - | 725932..726159 (-) | 228 | WP_010922077.1 | hypothetical protein | - |
| EL107_RS03615 (NCTC8302_00728) | - | 726159..727652 (-) | 1494 | WP_011018124.1 | phage minor capsid protein | - |
| EL107_RS03620 (NCTC8302_00729) | - | 727657..729159 (-) | 1503 | WP_011184804.1 | phage portal protein | - |
| EL107_RS03625 (NCTC8302_00730) | - | 729173..730464 (-) | 1292 | Protein_713 | PBSX family phage terminase large subunit | - |
| EL107_RS03630 (NCTC8302_00731) | - | 730467..730940 (-) | 474 | WP_011018127.1 | hypothetical protein | - |
| EL107_RS03635 (NCTC8302_00732) | - | 730991..731368 (-) | 378 | WP_002986841.1 | ASCH domain-containing protein | - |
| EL107_RS03640 | - | 731429..731905 (-) | 477 | WP_174148345.1 | GNAT family N-acetyltransferase | - |
| EL107_RS03645 (NCTC8302_00733) | - | 731821..732498 (-) | 678 | WP_011018129.1 | ABC transporter ATP-binding protein | - |
| EL107_RS03650 (NCTC8302_00734) | - | 732477..732995 (-) | 519 | WP_011018130.1 | ParB N-terminal domain-containing protein | - |
| EL107_RS03660 (NCTC8302_00735) | - | 733459..733899 (-) | 441 | WP_002990052.1 | ArpU family phage packaging/lysis transcriptional regulator | - |
| EL107_RS03665 (NCTC8302_00736) | - | 734173..734439 (-) | 267 | WP_011018131.1 | hypothetical protein | - |
| EL107_RS03670 (NCTC8302_00737) | - | 734436..734807 (-) | 372 | WP_011018132.1 | DUF1642 domain-containing protein | - |
| EL107_RS03675 (NCTC8302_00738) | - | 734928..735560 (-) | 633 | WP_011018133.1 | N-6 DNA methylase | - |
| EL107_RS03680 (NCTC8302_00739) | - | 735562..735846 (-) | 285 | WP_011018134.1 | hypothetical protein | - |
| EL107_RS09435 (NCTC8302_00740) | - | 735843..736013 (-) | 171 | WP_011018135.1 | hypothetical protein | - |
| EL107_RS03685 (NCTC8302_00741) | - | 736010..736414 (-) | 405 | WP_011018136.1 | YopX family protein | - |
| EL107_RS03690 (NCTC8302_00742) | - | 736411..736695 (-) | 285 | WP_011018137.1 | DUF3310 domain-containing protein | - |
| EL107_RS09675 (NCTC8302_00743) | - | 736689..736940 (-) | 252 | WP_011106665.1 | hypothetical protein | - |
| EL107_RS03700 (NCTC8302_00744) | - | 736937..737293 (-) | 357 | WP_011018138.1 | hypothetical protein | - |
| EL107_RS03705 (NCTC8302_00745) | - | 737290..737730 (-) | 441 | WP_011018139.1 | RusA family crossover junction endodeoxyribonuclease | - |
| EL107_RS03710 | - | 737730..737933 (-) | 204 | WP_011106686.1 | hypothetical protein | - |
| EL107_RS03715 (NCTC8302_00746) | ssbA | 737939..738358 (-) | 420 | WP_011018140.1 | single-stranded DNA-binding protein | Machinery gene |
| EL107_RS03720 (NCTC8302_00747) | - | 738351..739025 (-) | 675 | WP_011018141.1 | ERF family protein | - |
| EL107_RS03725 (NCTC8302_00748) | - | 739026..739508 (-) | 483 | WP_011018142.1 | siphovirus Gp157 family protein | - |
| EL107_RS03730 (NCTC8302_00749) | - | 739530..739784 (-) | 255 | WP_011018143.1 | hypothetical protein | - |
| EL107_RS03735 (NCTC8302_00750) | - | 739765..740121 (-) | 357 | WP_011018144.1 | HTH domain-containing protein | - |
| EL107_RS03740 (NCTC8302_00752) | - | 740269..741111 (-) | 843 | WP_011018146.1 | ATP-binding protein | - |
| EL107_RS03745 (NCTC8302_00753) | - | 741121..742041 (-) | 921 | WP_021340238.1 | phage replisome organizer N-terminal domain-containing protein | - |
| EL107_RS03750 (NCTC8302_00754) | - | 742055..742369 (-) | 315 | WP_021340228.1 | helix-turn-helix domain-containing protein | - |
| EL107_RS09660 (NCTC8302_00755) | - | 742385..742519 (-) | 135 | WP_021340229.1 | hypothetical protein | - |
| EL107_RS03755 (NCTC8302_00756) | - | 742550..742801 (-) | 252 | WP_021340237.1 | helix-turn-helix transcriptional regulator | - |
| EL107_RS09440 (NCTC8302_00758) | - | 743040..743207 (-) | 168 | WP_021340232.1 | hypothetical protein | - |
| EL107_RS03765 (NCTC8302_00759) | - | 743211..743930 (-) | 720 | WP_011018149.1 | phage antirepressor KilAC domain-containing protein | - |
| EL107_RS03770 (NCTC8302_00760) | - | 743958..744170 (-) | 213 | WP_023078130.1 | hypothetical protein | - |
| EL107_RS03775 (NCTC8302_00761) | - | 744368..744709 (+) | 342 | WP_011888679.1 | helix-turn-helix domain-containing protein | - |
| EL107_RS03780 (NCTC8302_00762) | - | 744693..745079 (+) | 387 | WP_032463929.1 | ImmA/IrrE family metallo-endopeptidase | - |
| EL107_RS03785 (NCTC8302_00763) | - | 745094..746515 (+) | 1422 | WP_011018151.1 | DUF4041 domain-containing protein | - |
| EL107_RS03790 (NCTC8302_00764) | - | 746693..747859 (+) | 1167 | WP_011018152.1 | tyrosine-type recombinase/integrase | - |
| EL107_RS03795 (NCTC8302_00765) | recX | 748007..748783 (+) | 777 | WP_011888675.1 | recombination regulator RecX | - |
| EL107_RS03800 (NCTC8302_00766) | - | 748863..749396 (+) | 534 | WP_002983693.1 | DUF402 domain-containing protein | - |
| EL107_RS03815 | - | 749874..750180 (+) | 307 | Protein_750 | IS110 family transposase | - |
| EL107_RS03880 (NCTC8302_00778) | - | 756521..757507 (-) | 987 | WP_126409741.1 | IS30-like element IS1239 family transposase | - |
Sequence
Protein
Download Length: 60 a.a. Molecular weight: 6935.81 Da Isoelectric Point: 3.9417
>NTDB_id=1121124 EL107_RS03490 WP_011018104.1 706364..706546(-) (prx) [Streptococcus pyogenes strain NCTC8302]
MLTYDEFKQAIDNGYITADTVMIVRKNGQIFDYVLPHEEARNGEVVTEEVVEEVMVELDK
MLTYDEFKQAIDNGYITADTVMIVRKNGQIFDYVLPHEEARNGEVVTEEVVEEVMVELDK
Nucleotide
Download Length: 183 bp
>NTDB_id=1121124 EL107_RS03490 WP_011018104.1 706364..706546(-) (prx) [Streptococcus pyogenes strain NCTC8302]
ATGCTAACATACGACGAATTTAAGCAAGCGATTGACAATGGATATATCACAGCAGACACAGTTATGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCGCATGAAGAAGCGAGAAATGGAGAAGTTGTGACCGAGGAGGTAGTGGAAGAAG
TGATGGTGGAATTAGACAAATAA
ATGCTAACATACGACGAATTTAAGCAAGCGATTGACAATGGATATATCACAGCAGACACAGTTATGATCGTGCGTAAAAA
CGGACAGATTTTTGATTATGTGTTGCCGCATGAAGAAGCGAGAAATGGAGAAGTTGTGACCGAGGAGGTAGTGGAAGAAG
TGATGGTGGAATTAGACAAATAA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS315 |
83.333 |
100 |
0.833 |
| prx | Streptococcus pyogenes MGAS315 |
83.333 |
100 |
0.833 |
| prx | Streptococcus pyogenes MGAS315 |
81.667 |
100 |
0.817 |
| prx | Streptococcus pyogenes MGAS315 |
81.667 |
100 |
0.817 |
| prx | Streptococcus pyogenes MGAS8232 |
80 |
100 |
0.8 |
| prx | Streptococcus pyogenes MGAS315 |
76.667 |
100 |
0.767 |
| prx | Streptococcus pyogenes MGAS315 |
93.023 |
71.667 |
0.667 |