Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   EL115_RS05580 Genome accession   NZ_LR134307
Coordinates   1112445..1113146 (-) Length   233 a.a.
NCBI ID   WP_003035055.1    Uniprot ID   -
Organism   Streptococcus milleri strain NCTC10708     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1107445..1118146
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL115_RS05560 (NCTC10708_01108) rnc 1109114..1109812 (-) 699 WP_126441471.1 ribonuclease III -
  EL115_RS09735 - 1109948..1110261 (-) 314 Protein_1063 DUF454 family protein -
  EL115_RS05570 (NCTC10708_01109) vicX 1110295..1111098 (-) 804 WP_039677204.1 MBL fold metallo-hydrolase Regulator
  EL115_RS05575 (NCTC10708_01110) micB 1111100..1112452 (-) 1353 WP_037596825.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL115_RS05580 (NCTC10708_01111) micA 1112445..1113146 (-) 702 WP_003035055.1 response regulator YycF Regulator
  EL115_RS05585 (NCTC10708_01112) - 1113447..1113779 (-) 333 WP_006268722.1 hypothetical protein -
  EL115_RS05590 (NCTC10708_01113) - 1113806..1115119 (-) 1314 WP_126441472.1 glycosyltransferase family 4 protein -
  EL115_RS05595 (NCTC10708_01114) - 1115121..1116119 (-) 999 WP_003068685.1 glycosyltransferase family 4 protein -
  EL115_RS05600 (NCTC10708_01115) ccpA 1116211..1117215 (-) 1005 WP_037596820.1 catabolite control protein A Regulator

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26868.85 Da        Isoelectric Point: 4.7415

>NTDB_id=1120893 EL115_RS05580 WP_003035055.1 1112445..1113146(-) (micA) [Streptococcus milleri strain NCTC10708]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFNGREALEMFEAERPDILILDLMLPELDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=1120893 EL115_RS05580 WP_003035055.1 1112445..1113146(-) (micA) [Streptococcus milleri strain NCTC10708]
ATGAAAAAAATATTAGTTGTAGATGATGAGAAACCAATCTCAGATATTATAAAATTTAACATGGTAAAAGAAGGTTATGA
AGTAGTGACAGCCTTCAATGGTCGTGAAGCATTAGAGATGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGACTTGA
TGTTGCCTGAACTGGACGGCTTAGAGGTGGCGCGAACGATTCGGAAAACGAGCAATGTTCCCATCATCGTTCTTTCTGCC
AAAGACAGTGAATTTGATAAAGTCATTGGTCTCGAAATCGGAGCAGATGACTATATGACAAAGCCGTTTTCTAATCGTGA
GTTACAGGCGCGTGTCAAAGCTATTTTGCGTCGCACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCGACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACCGATGCTTTTGTCGTGAAAAAGCATGGTGAAGAATTGGATTTAACACAC
CGTGAGTTTGAATTGCTACACCATTTGGCCACGCATATCGGGCAAGTAATGACGCGTGAACATCTACTAGAAACGGTGTG
GGGATATGATTATTTTGGAGATGTTCGGACTGTTGATGTGACAATTCGCCGTTTGAGAGAGAAGATTGAGGATATTCCTA
GCCGACCAGAGTATATTTTAACACGGCGCGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

83.262

100

0.833
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.415

98.283

0.446
  covR Streptococcus salivarius strain HSISS4

45.217

98.712

0.446
  scnR Streptococcus mutans UA159

36.052

100

0.361

Multiple sequence alignment