Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   EL115_RS05575 Genome accession   NZ_LR134307
Coordinates   1111100..1112452 (-) Length   450 a.a.
NCBI ID   WP_037596825.1    Uniprot ID   A0A7G9AWZ9
Organism   Streptococcus milleri strain NCTC10708     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1106100..1117452
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL115_RS05560 (NCTC10708_01108) rnc 1109114..1109812 (-) 699 WP_126441471.1 ribonuclease III -
  EL115_RS09735 - 1109948..1110261 (-) 314 Protein_1063 DUF454 family protein -
  EL115_RS05570 (NCTC10708_01109) vicX 1110295..1111098 (-) 804 WP_039677204.1 MBL fold metallo-hydrolase Regulator
  EL115_RS05575 (NCTC10708_01110) micB 1111100..1112452 (-) 1353 WP_037596825.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL115_RS05580 (NCTC10708_01111) micA 1112445..1113146 (-) 702 WP_003035055.1 response regulator YycF Regulator
  EL115_RS05585 (NCTC10708_01112) - 1113447..1113779 (-) 333 WP_006268722.1 hypothetical protein -
  EL115_RS05590 (NCTC10708_01113) - 1113806..1115119 (-) 1314 WP_126441472.1 glycosyltransferase family 4 protein -
  EL115_RS05595 (NCTC10708_01114) - 1115121..1116119 (-) 999 WP_003068685.1 glycosyltransferase family 4 protein -
  EL115_RS05600 (NCTC10708_01115) ccpA 1116211..1117215 (-) 1005 WP_037596820.1 catabolite control protein A Regulator

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51430.74 Da        Isoelectric Point: 4.7721

>NTDB_id=1120892 EL115_RS05575 WP_037596825.1 1111100..1112452(-) (micB) [Streptococcus milleri strain NCTC10708]
MIDNIRQFVVSRDFVFVLLILGFILVITLLSLENRRDNIRIRRLNQKVKDLIAGDYSEVLDMQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESEARKMNILKLLDVEDEYDLRDLITKVPV
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSIW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTETQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHHGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDELEG

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1120892 EL115_RS05575 WP_037596825.1 1111100..1112452(-) (micB) [Streptococcus milleri strain NCTC10708]
ATGATTGATAATATTAGACAATTTGTTGTATCAAGGGATTTTGTTTTTGTCTTACTTATTTTAGGATTTATTTTGGTCAT
TACGCTGCTCTCCTTGGAAAACAGACGTGATAATATTCGTATTCGCCGATTGAATCAAAAAGTGAAGGATTTAATCGCGG
GAGATTATTCAGAAGTTTTAGATATGCAAGGTGGTCCGGAAATTACTGATATTACAAATAGTATCAATGACTTATCTGAG
GTAATTCGCCTAACGCATGAAAATTTAGAGCAAGAAACCAAACGCTTGTCTAGTATTTTGTCCTATATGACAGATGGCGT
TCTTGCGACCAATCGTCGTGGGCAGATTATTATGATTAATGATATGGCGACCAAGCAATTGGGAGTCAAAGAATCTGAAG
CACGAAAGATGAATATCTTAAAATTGTTGGATGTTGAAGACGAATATGATTTACGAGACTTGATTACGAAAGTTCCAGTG
TTGACCATTGATTCGCAGGATGAAAATGGAGAGTTTTTAAGTTTACGTGTCCGATTTGCCTTGATTCGTCGAGAGTCAGG
CTTTATTTCAGGGCTGGTTGCTGTGCTGCACGATACAACGGAGCAGGAGAAAGAGGAGCGTGAGCGGAGACTATTTGTTT
CCAATGTTAGTCATGAATTGCGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCATTAGATGAAGGTGCCTTGTCA
GAACCAGTCGCACCAGATTTTATTAAGGTTTCATTAGATGAAACCAATCGGATGATGCGAATGGTTTCAGACTTGCTGAG
TTTGTCACGTATTGACAATGCTACCAGTCATTTGGATATTGAGCTGACGAATTTTACAGCTTTTATCACGTTTATTTTAA
ATCGTTTTGACAAAATCAGAAGTCAGAATGATGATAAAAAATATGAAATCATTCGTGATTACCCCATTAACTCCATCTGG
GTTGAAATTGATACGGATAAAATGACACAGGTTATTGATAATATCATCAATAATGCTATTAAATATTCTCCTGACGGCGG
TAAGATCACAGTGAGTATGAAAACAACCGAGACCCAAATGATTTTGTCTATATCAGATGAGGGCTTAGGGATTCCTAAAA
AAGATTTACCGAAAATTTTTGACCGCTTCTATCGTGTAGACAAAGCAAGAAGTCGTGCACAAGGTGGATCCGGATTAGGT
TTAGCTATTGCTAAGGAAATTATTAAGCAACATCACGGATTTATCTGGGCAAAGAGCGAGTATGGCAAAGGCTCAACCTT
TACTATTGTCCTGCCTTATGATAAGGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGAATTAGAAGGGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(95-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7G9AWZ9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

81.321

97.556

0.793
  vicK Streptococcus mutans UA159

70.905

90.889

0.644

Multiple sequence alignment