Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   EL097_RS00095 Genome accession   NZ_LR134293
Coordinates   27319..28029 (-) Length   236 a.a.
NCBI ID   WP_003047198.1    Uniprot ID   A0AAV3FQU3
Organism   Streptococcus canis strain NCTC12191     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 22319..33029
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL097_RS00080 (NCTC12191_00012) rnc 24367..25059 (-) 693 WP_003047203.1 ribonuclease III -
  EL097_RS00085 (NCTC12191_00013) vicX 25161..25970 (-) 810 WP_003047202.1 MBL fold metallo-hydrolase Regulator
  EL097_RS00090 (NCTC12191_00014) vicK 25974..27326 (-) 1353 WP_003047200.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL097_RS00095 (NCTC12191_00015) vicR 27319..28029 (-) 711 WP_003047198.1 response regulator YycF Regulator
  EL097_RS00100 (NCTC12191_00016) - 28207..29202 (-) 996 WP_099982909.1 DUF3114 domain-containing protein -
  EL097_RS10750 - 29411..29680 (-) 270 WP_003047194.1 hypothetical protein -
  EL097_RS00110 (NCTC12191_00017) - 30076..30786 (-) 711 WP_003047191.1 MIP/aquaporin family protein -
  EL097_RS00115 (NCTC12191_00018) dhaM 30800..31174 (-) 375 WP_003047188.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  EL097_RS00120 (NCTC12191_00019) dhaL 31174..31749 (-) 576 WP_003047186.1 dihydroxyacetone kinase subunit DhaL -
  EL097_RS00125 (NCTC12191_00020) dhaK 31760..32749 (-) 990 WP_003047183.1 dihydroxyacetone kinase subunit DhaK -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27057.91 Da        Isoelectric Point: 4.9038

>NTDB_id=1120472 EL097_RS00095 WP_003047198.1 27319..28029(-) (vicR) [Streptococcus canis strain NCTC12191]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTVFEEEKPDLIILDLMLPELDGLEVAKEIRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGQEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1120472 EL097_RS00095 WP_003047198.1 27319..28029(-) (vicR) [Streptococcus canis strain NCTC12191]
ATGAAAAAAATACTGATTGTGGATGATGAAAAACCGATTTCTGACATTATTAAGTTTAACTTGACAAAAGAAGGTTATGA
CATTGTGACCGCTTTTGATGGCCGCGAAGCGGTTACTGTTTTTGAAGAAGAAAAGCCAGATCTCATTATTCTTGATTTGA
TGCTGCCCGAACTTGATGGACTTGAAGTAGCCAAAGAAATTCGTAAAACTAGCCATATCCCTATTATCATGCTGTCTGCT
AAAGACAGTGAGTTTGACAAGGTTATTGGTCTTGAAATTGGAGCAGATGATTATGTGACGAAACCCTTCTCCAACCGTGA
ATTGTTGGCGCGTGTCAAAGCTCATTTACGTCGAACAGAGACCATTGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCTG
GTTCGCAAGAATTGACCATTGGTAATTTGCAAATTTTACCCGATGCTTTTGTGGCCAAAAAACATGGTCAAGAGGTGGAA
TTAACCCATCGTGAATTTGAATTATTACATCATCTAGCCAATCACATGGGGCAAGTAATGACACGTGAGCATCTACTTGA
AACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTTGATGTGACTGTTCGCCGCTTACGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTGACGAGACGTGGTGTTGGGTATTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.06

99.153

0.784
  covR Streptococcus salivarius strain HSISS4

44.828

98.305

0.441
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

38.136

100

0.381

Multiple sequence alignment