Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   EL097_RS00090 Genome accession   NZ_LR134293
Coordinates   25974..27326 (-) Length   450 a.a.
NCBI ID   WP_003047200.1    Uniprot ID   A0AAV3FQK4
Organism   Streptococcus canis strain NCTC12191     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 20974..32326
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL097_RS00080 (NCTC12191_00012) rnc 24367..25059 (-) 693 WP_003047203.1 ribonuclease III -
  EL097_RS00085 (NCTC12191_00013) vicX 25161..25970 (-) 810 WP_003047202.1 MBL fold metallo-hydrolase Regulator
  EL097_RS00090 (NCTC12191_00014) vicK 25974..27326 (-) 1353 WP_003047200.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL097_RS00095 (NCTC12191_00015) vicR 27319..28029 (-) 711 WP_003047198.1 response regulator YycF Regulator
  EL097_RS00100 (NCTC12191_00016) - 28207..29202 (-) 996 WP_099982909.1 DUF3114 domain-containing protein -
  EL097_RS10750 - 29411..29680 (-) 270 WP_003047194.1 hypothetical protein -
  EL097_RS00110 (NCTC12191_00017) - 30076..30786 (-) 711 WP_003047191.1 MIP/aquaporin family protein -
  EL097_RS00115 (NCTC12191_00018) dhaM 30800..31174 (-) 375 WP_003047188.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  EL097_RS00120 (NCTC12191_00019) dhaL 31174..31749 (-) 576 WP_003047186.1 dihydroxyacetone kinase subunit DhaL -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51462.98 Da        Isoelectric Point: 5.4007

>NTDB_id=1120471 EL097_RS00090 WP_003047200.1 25974..27326(-) (vicK) [Streptococcus canis strain NCTC12191]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEQALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEEDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1120471 EL097_RS00090 WP_003047200.1 25974..27326(-) (vicK) [Streptococcus canis strain NCTC12191]
ATGACTAGAGATATCATCGGGAATTTATCCGCTTTTGAATTAGCGATTCTCTTATTGCTTGTTTTTGTTGCCTTTTACTT
TATTCATTTAGCAGTGCGGGATTACCGCAATGCTCGTATTATTCGAATGATGAGCCACAAGATCAGGGATCTGATCAATG
GTCGTTATACCGATATGATTAACGAAAAGGCTGACATTGAATTGATGGAATTGGCAGATCAATTAAACGATCTTTCAGAT
GTTTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTTAATCTGACCAAGGAGCAGG
CTCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTACGTTTACGCTTCGCTTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCCTCACA
GAAGATATTGCGCCAAGCTTTATCAAGGTTTCTCTTGATGAGACCAATCGAATGATGCGAATGATTTCCGATCTTTTGAA
CCTGTCTCGCATTGATAACCAAGTGACCCAGTTGTCAGTCGAAATGACCAATTTCACAGCCTTTATGACCTCTATTCTGA
ACCGATTTGACCTAGTTAAAAACCAACATACGGGTACAGGCAAGGTCTATGAAATTGTGAGGGATTACCCCATTACTTCT
GTTTGGTTAGAAATTGACAATGACAAGATGACACAGGTTATTGAAAATATTCTTAATAATGCCATTAAATATTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACAGACACGCAGTTGATTATTTCCATTTCTGATCAGGGTCTCGGCATTC
CTAAAAAGGATTTGCCCCTTATTTTTGACCGATTTTACCGTGTGGACAAGGCAAGAAGTCGTGCCCAGGGCGGTACTGGA
CTAGGCCTTGCCATTGCTAAAGAAATTATCAAGCAGCATCACGGCTTCATCTGGGCTAAAAGTGATTATGGCAAGGGATC
AACCTTTACCATTGTCTTGCCTTATGAAAAAGATGCTGCCATTTATGAAGAATGGGAGGAAGATATAGATTAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

PAS fold (PAS)

(95-165)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.913

92

0.68
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631

Multiple sequence alignment