Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   EL084_RS05930 Genome accession   NZ_LR134292
Coordinates   1213812..1214522 (-) Length   236 a.a.
NCBI ID   WP_021142846.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC10389     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1208812..1219522
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL084_RS05915 (NCTC10389_01252) rnc 1210761..1211447 (-) 687 WP_004232787.1 ribonuclease III -
  EL084_RS05920 (NCTC10389_01253) vicX 1211657..1212466 (-) 810 WP_004232789.1 MBL fold metallo-hydrolase Regulator
  EL084_RS05925 (NCTC10389_01254) vicK 1212467..1213819 (-) 1353 WP_115255368.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL084_RS05930 (NCTC10389_01255) vicR 1213812..1214522 (-) 711 WP_021142846.1 response regulator YycF Regulator
  EL084_RS05935 (NCTC10389_01256) - 1214830..1215594 (+) 765 WP_126440484.1 amino acid ABC transporter ATP-binding protein -
  EL084_RS05940 (NCTC10389_01257) - 1215605..1216408 (+) 804 WP_126440487.1 transporter substrate-binding domain-containing protein -
  EL084_RS05945 (NCTC10389_01258) - 1216424..1217128 (+) 705 WP_004232799.1 amino acid ABC transporter permease -
  EL084_RS05950 (NCTC10389_01259) - 1217138..1217785 (+) 648 WP_004232801.1 amino acid ABC transporter permease -
  EL084_RS05955 (NCTC10389_01260) - 1217817..1218425 (-) 609 WP_126440490.1 TVP38/TMEM64 family protein -
  EL084_RS05960 (NCTC10389_01261) - 1218642..1218938 (-) 297 WP_004232805.1 hypothetical protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27179.94 Da        Isoelectric Point: 4.6553

>NTDB_id=1120449 EL084_RS05930 WP_021142846.1 1213812..1214522(-) (vicR) [Streptococcus equinus strain NCTC10389]
MKKILIVDDEKPISDIIKFNLTKEGYETVTAFDGREAIEKFEEENPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIESAVAEENASSSNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1120449 EL084_RS05930 WP_021142846.1 1213812..1214522(-) (vicR) [Streptococcus equinus strain NCTC10389]
ATGAAAAAAATTCTTATTGTTGATGATGAAAAACCAATTTCAGATATTATTAAATTTAATTTAACTAAAGAAGGTTACGA
AACAGTTACGGCTTTTGATGGTCGTGAAGCTATTGAAAAATTTGAAGAAGAAAATCCTGATTTGATTATTTTGGATTTGA
TGTTGCCAGAATTGGACGGACTTGAAGTCGCAAAAGAAGTTCGTAAAACGAGTCATATTCCTATTATTATGCTATCAGCA
AAAGATAGTGAATTTGATAAAGTTATCGGTCTTGAAATTGGTGCTGACGACTACGTGACAAAACCATTTTCAAACCGCGA
ATTGTTGGCTCGTGTCAAAGCACACCTTCGCCGCACTGAAAATATCGAATCTGCAGTTGCTGAAGAAAATGCGTCTTCTT
CAAACTCAGAAATCACAATCGGTGACTTGAAAATCTTGCCTGATGCATTTGTGGCACAAAAACGTGGTGAAGACATTGAA
TTAACACACCGTGAGTTTGAATTGTTGCATCATTTGGCAACTCACATGGGACAAGTAATGACACGTGAATACCTTTTGGA
AACTGTCTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGACGTAACAATCCGTCGTTTGCGTGAAAAAATCGAAG
ACACACCAAGTCGTCCAGAATATATTTTGACACGTCGTGGTGTTGGATATTACATGAAGTCTTATGAATAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)

Response regulator receiver domain (Response_reg)

(4-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.678

100

0.907
  micA Streptococcus pneumoniae Cp1015

78.632

99.153

0.78
  covR Streptococcus salivarius strain HSISS4

47.414

98.305

0.466
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.121

98.305

0.453
  scnR Streptococcus mutans UA159

36.864

100

0.369

Multiple sequence alignment