Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   EL084_RS05925 Genome accession   NZ_LR134292
Coordinates   1212467..1213819 (-) Length   450 a.a.
NCBI ID   WP_115255368.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC10389     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1207467..1218819
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL084_RS05915 (NCTC10389_01252) rnc 1210761..1211447 (-) 687 WP_004232787.1 ribonuclease III -
  EL084_RS05920 (NCTC10389_01253) vicX 1211657..1212466 (-) 810 WP_004232789.1 MBL fold metallo-hydrolase Regulator
  EL084_RS05925 (NCTC10389_01254) vicK 1212467..1213819 (-) 1353 WP_115255368.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EL084_RS05930 (NCTC10389_01255) vicR 1213812..1214522 (-) 711 WP_021142846.1 response regulator YycF Regulator
  EL084_RS05935 (NCTC10389_01256) - 1214830..1215594 (+) 765 WP_126440484.1 amino acid ABC transporter ATP-binding protein -
  EL084_RS05940 (NCTC10389_01257) - 1215605..1216408 (+) 804 WP_126440487.1 transporter substrate-binding domain-containing protein -
  EL084_RS05945 (NCTC10389_01258) - 1216424..1217128 (+) 705 WP_004232799.1 amino acid ABC transporter permease -
  EL084_RS05950 (NCTC10389_01259) - 1217138..1217785 (+) 648 WP_004232801.1 amino acid ABC transporter permease -
  EL084_RS05955 (NCTC10389_01260) - 1217817..1218425 (-) 609 WP_126440490.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51387.34 Da        Isoelectric Point: 4.7752

>NTDB_id=1120448 EL084_RS05925 WP_115255368.1 1212467..1213819(-) (vicK) [Streptococcus equinus strain NCTC10389]
MNNIISQNQYLFEQAILFLLAFVAVYFIHLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELAGRLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRSGNITMINQTAQQQLNLEREEALGMNIVDILGDDSDYTYHDLVSKTPD
IVLNRRDETGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTVAGKQYEIVRDYPIKS
IWLEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSDIYDEWEDDED

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1120448 EL084_RS05925 WP_115255368.1 1212467..1213819(-) (vicK) [Streptococcus equinus strain NCTC10389]
ATGAATAATATAATATCACAGAATCAGTATCTGTTTGAGCAGGCAATCTTGTTTTTGCTCGCTTTTGTCGCTGTTTATTT
TATTCATTTAGCGATAAGAGATTATCGAACTTCAGTTAATATTCGTCGTTTGAGTGGTAAGGTTCGTGAGCTTATCACTG
GTAAATACACTGAAGACATCATTATTGAAAAAGATAGAGATTTGGCTGAACTTGCTGGTCGGTTAAATGACTTGTCTACG
GTTTTTCGCTTGGCTCAGGAAAATCTTGCGCAGGAAAAAAATCGTTTGGCTAGTATTTTGTCTTATATGACTGACGGTGT
CTTGGCTACTGACCGTTCTGGAAATATCACTATGATTAACCAGACAGCTCAGCAGCAACTTAATCTTGAACGTGAAGAAG
CTCTTGGAATGAATATTGTTGATATTCTTGGGGACGATAGCGATTATACCTACCATGATTTGGTTTCTAAGACACCTGAT
ATTGTTCTAAATCGTCGCGATGAGACAGGTGAATTTATCACTTTGCGAATTCGTTTTGCGCTGAATCGTCGTGATAGTGG
CTTTATCTCAGGCTTGATTGCTGTTTTACATGATACAACGGAACAAGAAAAAGAAGACCGTGAACGTCGTTTATTCGTAT
CAAATGTTAGTCACGAATTGCGTACACCGTTGACATCTGTGAAATCGTATTTGGAAGCTTTGGATGAAGGTGCACTTAAA
GAAGATATTGCACCAAGTTTTATTAAAGTTTCTCTTGATGAAACAAACCGTATGATTCGAATGATTTCTGATTTGCTCAA
TTTGTCTCGAATTGATAATCAGACTGTTCAGCTTGAAGTTGAAATGACTAACTTTACAGCATTTATGACATCAATTTTGA
ACCGTTTTGACCAAATTAAGAGTCAACATACAGTCGCTGGTAAGCAGTATGAGATTGTCAGAGATTATCCGATCAAGTCT
ATCTGGTTAGAAATTGACCCAGATAAAATGACGCAAGTTCTGGATAACATCCTTAATAATGCAATTAAGTATTCGCCAGA
TGGTGGTAAAATCACTGTCAGCATGAAGACGACTGAGACACAGTTGATTATTTCAATTTCTGATGAAGGTCTTGGTATTC
CTAAGAAAGATTTGCCGCTAATCTTTGACCGATTCTATCGTGTTGACAAGGCTAGAAGTCGTGCTCAAGGTGGTTCAGGA
CTTGGTCTTGCGATTGCAAAAGAAATTGTTAAACAACACAAAGGATTTATTTGGGCTCAAAGTACTTATGGAAAAGGCTC
AACCTTTACAATTGTTCTTCCGTATGAGAAGGATTCTGATATTTATGACGAATGGGAGGATGACGAGGACTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-189)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

76.627

92.222

0.707
  micB Streptococcus pneumoniae Cp1015

65.802

94.222

0.62

Multiple sequence alignment