Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   EL084_RS03765 Genome accession   NZ_LR134292
Coordinates   760932..761774 (-) Length   280 a.a.
NCBI ID   WP_126440198.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC10389     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 707676..787141 760932..761774 within 0


Gene organization within MGE regions


Location: 707676..787141
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL084_RS03520 (NCTC10389_00750) - 708258..708854 (+) 597 WP_004231532.1 L-threonylcarbamoyladenylate synthase -
  EL084_RS03525 (NCTC10389_00751) glyA 708962..710212 (+) 1251 WP_126440170.1 serine hydroxymethyltransferase -
  EL084_RS03530 (NCTC10389_00752) - 710255..711232 (+) 978 WP_126440171.1 nucleoid-associated protein -
  EL084_RS03535 (NCTC10389_00753) - 711232..711834 (+) 603 WP_115255137.1 lysozyme family protein -
  EL084_RS03540 (NCTC10389_00754) - 711857..713578 (+) 1722 WP_126440172.1 ABC transporter ATP-binding protein -
  EL084_RS03545 (NCTC10389_00755) - 713582..715318 (+) 1737 WP_126440173.1 ABC transporter ATP-binding protein -
  EL084_RS03550 (NCTC10389_00756) - 715396..716652 (-) 1257 WP_126440131.1 ISL3 family transposase -
  EL084_RS03555 (NCTC10389_00757) - 716810..718267 (-) 1458 WP_126440174.1 alpha-amylase -
  EL084_RS03560 (NCTC10389_00758) - 718372..718866 (-) 495 WP_232007697.1 TVP38/TMEM64 family protein -
  EL084_RS03565 (NCTC10389_00759) guaA 719273..720835 (+) 1563 WP_126440175.1 glutamine-hydrolyzing GMP synthase -
  EL084_RS03570 - 721286..721819 (+) 534 WP_232007698.1 NUDIX hydrolase -
  EL084_RS03575 (NCTC10389_00760) - 721740..722246 (+) 507 WP_126440176.1 GNAT family N-acetyltransferase -
  EL084_RS03580 (NCTC10389_00761) - 722239..722517 (-) 279 Protein_679 transposase -
  EL084_RS03585 (NCTC10389_00762) - 722696..722893 (+) 198 WP_232007699.1 hypothetical protein -
  EL084_RS03590 (NCTC10389_00763) - 722944..723615 (+) 672 WP_126440177.1 methyltransferase family protein -
  EL084_RS03595 (NCTC10389_00764) - 723772..724224 (+) 453 WP_232007700.1 Rgg/GadR/MutR family transcriptional regulator -
  EL084_RS09210 (NCTC10389_00765) - 724249..724623 (+) 375 WP_232007701.1 hypothetical protein -
  EL084_RS09215 - 724636..724959 (+) 324 Protein_684 glucan-binding protein -
  EL084_RS09095 (NCTC10389_00767) - 725334..725777 (+) 444 WP_197716199.1 CPBP family intramembrane glutamic endopeptidase -
  EL084_RS03610 (NCTC10389_00768) - 725926..727251 (+) 1326 WP_126440178.1 MATE family efflux transporter -
  EL084_RS03615 (NCTC10389_00769) - 727482..727925 (+) 444 WP_164557744.1 DAK2 domain-containing protein -
  EL084_RS03620 (NCTC10389_00770) dhaM 727975..728358 (+) 384 WP_126440179.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  EL084_RS03625 (NCTC10389_00771) - 728478..729164 (+) 687 WP_126440180.1 helix-turn-helix transcriptional regulator -
  EL084_RS03630 (NCTC10389_00772) - 729166..729369 (+) 204 WP_004231610.1 hypothetical protein -
  EL084_RS03635 (NCTC10389_00773) - 729370..730785 (+) 1416 WP_126440181.1 Y-family DNA polymerase -
  EL084_RS03640 (NCTC10389_00774) - 730787..731146 (+) 360 WP_126440182.1 hypothetical protein -
  EL084_RS03645 (NCTC10389_00775) - 731143..731352 (+) 210 WP_126440183.1 hypothetical protein -
  EL084_RS03650 (NCTC10389_00776) - 731449..732126 (+) 678 WP_126440184.1 methylase -
  EL084_RS03655 (NCTC10389_00777) - 732131..736498 (+) 4368 WP_126440185.1 Eco57I restriction-modification methylase domain-containing protein -
  EL084_RS03660 (NCTC10389_00778) - 736620..738761 (+) 2142 WP_164557726.1 AAA family ATPase -
  EL084_RS03665 (NCTC10389_00779) - 738746..740695 (+) 1950 WP_126440187.1 UvrD-helicase domain-containing protein -
  EL084_RS03670 (NCTC10389_00780) - 740893..741591 (+) 699 WP_115255153.1 GntR family transcriptional regulator -
  EL084_RS03675 (NCTC10389_00781) - 741892..742224 (+) 333 WP_004231629.1 putative DNA-binding protein -
  EL084_RS03680 (NCTC10389_00782) ffh 742271..743836 (+) 1566 WP_126440188.1 signal recognition particle protein -
  EL084_RS09520 - 743846..743992 (+) 147 WP_126440189.1 DUF3307 domain-containing protein -
  EL084_RS09525 - 744112..744333 (+) 222 Protein_702 DUF3307 domain-containing protein -
  EL084_RS03690 (NCTC10389_00783) - 744585..745127 (+) 543 WP_020916716.1 YqeG family HAD IIIA-type phosphatase -
  EL084_RS03695 (NCTC10389_00784) - 745132..745968 (+) 837 WP_004231637.1 VanW family protein -
  EL084_RS03700 (NCTC10389_00785) - 746072..746737 (-) 666 WP_126440190.1 hypothetical protein -
  EL084_RS03705 - 747080..747199 (-) 120 WP_126440191.1 helix-turn-helix domain-containing protein -
  EL084_RS09000 - 747551..747733 (+) 183 WP_164557716.1 hypothetical protein -
  EL084_RS09380 - 747748..747876 (+) 129 WP_268921735.1 hypothetical protein -
  EL084_RS03715 (NCTC10389_00786) xerS 748579..749649 (+) 1071 WP_004231646.1 tyrosine recombinase XerS -
  EL084_RS03720 (NCTC10389_00787) - 749811..750755 (-) 945 WP_126440192.1 sensor histidine kinase -
  EL084_RS03725 (NCTC10389_00788) - 750752..751414 (-) 663 WP_126440193.1 response regulator transcription factor -
  EL084_RS03730 (NCTC10389_00789) - 751514..753499 (-) 1986 WP_126440194.1 FtsX-like permease family protein -
  EL084_RS03735 (NCTC10389_00790) - 753501..754253 (-) 753 WP_126440195.1 ABC transporter ATP-binding protein -
  EL084_RS03740 (NCTC10389_00793) - 754689..755510 (-) 822 WP_126440196.1 sugar phosphate isomerase/epimerase family protein -
  EL084_RS03745 (NCTC10389_00794) trmFO 755538..756875 (-) 1338 WP_126440197.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  EL084_RS03750 - 757061..757784 (-) 724 Protein_716 DUF3307 domain-containing protein -
  EL084_RS03755 - 757799..758449 (-) 651 Protein_717 SatD family protein -
  EL084_RS03760 (NCTC10389_00798) topA 758589..760727 (-) 2139 WP_004231665.1 type I DNA topoisomerase -
  EL084_RS03765 (NCTC10389_00799) dprA 760932..761774 (-) 843 WP_126440198.1 DNA-processing protein DprA Machinery gene
  EL084_RS03770 (NCTC10389_00800) - 761844..762395 (-) 552 WP_126440199.1 sugar O-acetyltransferase -
  EL084_RS03775 (NCTC10389_00801) - 762395..763174 (-) 780 WP_126440200.1 ribonuclease HII -
  EL084_RS03780 (NCTC10389_00802) ylqF 763161..764015 (-) 855 WP_126440201.1 ribosome biogenesis GTPase YlqF -
  EL084_RS03785 (NCTC10389_00803) - 764229..764636 (+) 408 WP_004231682.1 DUF4231 domain-containing protein -
  EL084_RS03790 (NCTC10389_00804) - 764843..765164 (-) 322 Protein_724 hypothetical protein -
  EL084_RS03795 (NCTC10389_00805) - 765441..766979 (-) 1539 WP_126440202.1 ABC-F family ATP-binding cassette domain-containing protein -
  EL084_RS03800 (NCTC10389_00806) - 767139..767696 (-) 558 WP_004231690.1 ECF transporter S component -
  EL084_RS03805 (NCTC10389_00807) - 767693..768553 (-) 861 WP_126440203.1 pyridoxamine kinase -
  EL084_RS03810 (NCTC10389_00808) - 768691..769956 (+) 1266 WP_126440204.1 PLP-dependent aminotransferase family protein -
  EL084_RS03815 (NCTC10389_00809) dapA 769999..770934 (-) 936 WP_126440205.1 4-hydroxy-tetrahydrodipicolinate synthase -
  EL084_RS03820 (NCTC10389_00810) - 771020..772096 (-) 1077 WP_004231696.1 aspartate-semialdehyde dehydrogenase -
  EL084_RS03830 (NCTC10389_00812) cls 772461..774059 (-) 1599 WP_126440206.1 cardiolipin synthase -
  EL084_RS03835 (NCTC10389_00813) - 774165..775835 (-) 1671 WP_126440207.1 formate--tetrahydrofolate ligase -
  EL084_RS03840 (NCTC10389_00814) - 776182..776868 (+) 687 WP_126440208.1 phosphopantothenate--cysteine ligase -
  EL084_RS03845 (NCTC10389_00815) coaC 776861..777400 (+) 540 WP_004231706.1 phosphopantothenoylcysteine decarboxylase -
  EL084_RS03850 (NCTC10389_00816) - 777504..778076 (+) 573 WP_024344070.1 ECF transporter S component -
  EL084_RS03855 (NCTC10389_00817) - 778295..780010 (+) 1716 WP_126440209.1 phospho-sugar mutase -
  EL084_RS03860 (NCTC10389_00818) - 780178..781437 (-) 1260 WP_126440210.1 NRAMP family divalent metal transporter -
  EL084_RS03865 (NCTC10389_00819) - 781621..782589 (-) 969 WP_126440211.1 DUF1002 domain-containing protein -
  EL084_RS03870 (NCTC10389_00820) - 782666..783079 (-) 414 WP_126440212.1 VOC family protein -
  EL084_RS03875 (NCTC10389_00821) - 783155..783901 (-) 747 WP_126440213.1 class A sortase -
  EL084_RS03880 (NCTC10389_00822) gyrA 783933..786362 (-) 2430 WP_126440214.1 DNA gyrase subunit A -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 30901.82 Da        Isoelectric Point: 8.4541

>NTDB_id=1120437 EL084_RS03765 WP_126440198.1 760932..761774(-) (dprA) [Streptococcus equinus strain NCTC10389]
MNNFELFKLKQAGLTNLNILALLDYQSKQEKSLSLRDMAVASKCKNPILFMEKYKSLDSKSLRQIFNQYPSISILDDEYP
IELKNCYNPPVFLFYQGNVDLLKRLKMAVVGARTASQTGTKSVQKIVSELGNQFVIVSGLARGIDTSAHISALKNGGATI
AVIGCGLDVHYPKENKLLQEYLGKNHLILSEYAVGEAPLKFHFPERNRIIAGLSQGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIKEGAKCITSGMDVLSEYQL

Nucleotide


Download         Length: 843 bp        

>NTDB_id=1120437 EL084_RS03765 WP_126440198.1 760932..761774(-) (dprA) [Streptococcus equinus strain NCTC10389]
ATGAACAATTTTGAATTATTTAAATTAAAACAAGCAGGACTGACTAATCTTAATATTTTAGCCCTTTTAGATTATCAGAG
TAAACAAGAAAAATCTTTGTCCTTGCGAGATATGGCTGTAGCTTCAAAGTGTAAGAATCCAATTCTTTTCATGGAAAAAT
ACAAATCTCTTGATAGTAAATCATTGCGCCAAATTTTTAATCAGTATCCTAGTATTTCAATACTAGACGATGAATATCCA
ATAGAATTGAAGAATTGCTATAATCCACCTGTTTTTCTCTTTTACCAAGGCAACGTAGATTTGCTTAAACGTCTGAAAAT
GGCAGTAGTAGGAGCGAGGACAGCCTCTCAAACAGGAACAAAATCTGTTCAAAAGATTGTTAGTGAACTCGGAAATCAGT
TTGTTATTGTTAGTGGGTTGGCGCGTGGAATTGACACAAGTGCACACATTTCAGCGTTAAAAAATGGCGGAGCAACTATA
GCTGTTATCGGCTGTGGCTTAGACGTTCATTACCCTAAAGAAAACAAGCTATTGCAAGAATATCTAGGTAAAAATCACCT
AATTCTAAGTGAGTATGCAGTAGGAGAGGCTCCACTAAAATTCCACTTTCCAGAACGCAATCGCATCATTGCGGGATTGT
CTCAAGGTGTTATTGTAGCAGAAGCAAAAATGCGTTCAGGTAGTTTAATTACTTGTGAGAGAGCAATGGAAGAAGGACGA
GATGTTTTTGCAATTCCAGGAAATATCTTGGATGGAAAATCCGACGGTTGCCATCACCTGATAAAGGAAGGTGCAAAATG
CATTACATCAGGCATGGATGTCCTCTCAGAATACCAATTATAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(71-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

72.5

100

0.725
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae D39

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae R6

63.929

100

0.639
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.929

100

0.639
  dprA/cilB/dalA Streptococcus mitis SK321

63.929

100

0.639
  dprA Lactococcus lactis subsp. cremoris KW2

60.072

99.286

0.596
  dprA Bacillus subtilis subsp. subtilis str. 168

40.892

96.071

0.393
  dprA Latilactobacillus sakei subsp. sakei 23K

39.768

92.5

0.368

Multiple sequence alignment