Detailed information NTG1120391

Bioinformatically predicted

Overview

• Name: comYD
• Type: Machinery gene
• Locus tag: EL092_RS09580
• Genome accession: NZ_LR134291
• Coordinates: 1989877..1990305 (-)
• Length: 142 a.a.
• NCBI ID: WP_012130939.1
• Uniprot ID: A8AZH7
• Organism: Streptococcus gordonii strain NCTC7868
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1984877..1995305

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL092_RS09550 (NCTC7868_01909)	-	1985842..1986507 (-)	666	WP_012130933.1	CPBP family intramembrane glutamic endopeptidase	-
EL092_RS09555 (NCTC7868_01910)	-	1986555..1987745 (-)	1191	WP_012130934.1	acetate kinase	-
EL092_RS09560 (NCTC7868_01911)	comYH	1987795..1988748 (-)	954	WP_012130935.1	class I SAM-dependent methyltransferase	Machinery gene
EL092_RS09565 (NCTC7868_01912)	comGG	1988779..1989210 (-)	432	WP_223341947.1	competence type IV pilus minor pilin ComGG	-
EL092_RS09570 (NCTC7868_01913)	comGF/cglF	1989191..1989628 (-)	438	WP_012130937.1	competence type IV pilus minor pilin ComGF	Machinery gene
EL092_RS09575 (NCTC7868_01914)	comGE/cglE	1989612..1989905 (-)	294	WP_012130938.1	competence type IV pilus minor pilin ComGE	Machinery gene
EL092_RS09580 (NCTC7868_01915)	comYD	1989877..1990305 (-)	429	WP_012130939.1	competence type IV pilus minor pilin ComGD	Machinery gene
EL092_RS09585 (NCTC7868_01916)	comYC	1990265..1990582 (-)	318	WP_012130940.1	competence type IV pilus major pilin ComGC	Machinery gene
EL092_RS09590 (NCTC7868_01917)	comYB	1990579..1991613 (-)	1035	WP_012130941.1	competence type IV pilus assembly protein ComGB	Machinery gene
EL092_RS09595 (NCTC7868_01918)	comYA	1991525..1992484 (-)	960	WP_012130942.1	competence type IV pilus ATPase ComGA	Machinery gene
EL092_RS09600 (NCTC7868_01919)	-	1992586..1992954 (-)	369	WP_012130943.1	DUF1033 family protein	-

Sequence

Protein

• Length: 142 a.a.
• Molecular weight: 16043.65 Da
• Isoelectric Point: 10.1975

>NTDB_id=1120391 EL092_RS09580 WP_012130939.1 1989877..1990305(-) (comYD) [Streptococcus gordonii strain NCTC7868]
MVRTIVRLRQLPIKAFTVLESLLVLMISSFILLALSSSVQATFEQIQAKIFFLEFEHFYQESQKLSVSSQRKLVLEISSQ
EISNGYARLPIPKGIQAPESTQIYFDKAGGNSSLSKVQFQTKEGLVTYQLYIGNGKFKKTTN

Nucleotide

• Length: 429 bp

>NTDB_id=1120391 EL092_RS09580 WP_012130939.1 1989877..1990305(-) (comYD) [Streptococcus gordonii strain NCTC7868]
ATGGTAAGAACAATAGTGAGACTCAGGCAGTTGCCAATTAAGGCCTTTACGGTTTTGGAAAGCCTCTTGGTCTTGATGAT
TAGCAGTTTTATCTTGCTGGCTTTATCAAGCTCTGTTCAAGCTACATTTGAACAGATTCAGGCAAAGATCTTCTTTTTAG
AATTTGAGCATTTTTATCAGGAAAGTCAGAAGCTTAGCGTATCTTCTCAGAGAAAGCTGGTGCTAGAAATATCCAGTCAA
GAGATTTCAAATGGTTATGCTCGTCTTCCAATTCCTAAAGGAATCCAAGCACCTGAATCTACACAGATCTATTTTGATAA
GGCTGGTGGTAATTCTTCACTCAGTAAAGTTCAGTTTCAAACCAAGGAAGGACTGGTGACCTATCAACTCTATATTGGAA
ATGGCAAATTTAAGAAAACGACAAATTAA

Domains

No domain identified.

3D structure

• AlphaFold DB: A8AZH7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYD	Streptococcus gordonii str. Challis substr. CH1	100	100	1
comGD/cglD	Streptococcus pneumoniae TIGR4	59.055	89.437	0.528
comGD/cglD	Streptococcus mitis SK321	59.055	89.437	0.528
comGD/cglD	Streptococcus pneumoniae Rx1	59.055	89.437	0.528
comGD/cglD	Streptococcus pneumoniae D39	59.055	89.437	0.528
comGD/cglD	Streptococcus pneumoniae R6	59.055	89.437	0.528
comGD/cglD	Streptococcus mitis NCTC 12261	55.97	94.366	0.528
comYD	Streptococcus mutans UA140	50.388	90.845	0.458
comYD	Streptococcus mutans UA159	50.388	90.845	0.458
comGD	Lactococcus lactis subsp. cremoris KW2	36.879	99.296	0.366