Detailed information NTG1120287

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: EL087_RS09215
• Genome accession: NZ_LR134288
• Coordinates: 1854565..1855755 (+)
• Length: 396 a.a.
• NCBI ID: WP_126408101.1
• Uniprot ID: -
• Organism: Streptococcus milleri strain NCTC11169
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1849565..1860755

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL087_RS09175 (NCTC11169_01888)	-	1850047..1850904 (-)	858	WP_126408099.1	transposase	-
EL087_RS09190 (NCTC11169_01891)	comE	1851373..1852122 (-)	750	WP_003029521.1	competence system response regulator transcription factor ComE	Regulator
EL087_RS09195 (NCTC11169_01892)	comD/comD2	1852122..1853444 (-)	1323	WP_218969867.1	sensor histidine kinase	Regulator
EL087_RS09200 (NCTC11169_01893)	-	1853465..1853611 (-)	147	WP_003029519.1	bacteriocin	-
EL087_RS09210 (NCTC11169_01895)	rlmH	1853893..1854372 (-)	480	WP_049533214.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
EL087_RS09215 (NCTC11169_01896)	htrA	1854565..1855755 (+)	1191	WP_126408101.1	S1C family serine protease	Regulator
EL087_RS09220 (NCTC11169_01897)	spo0J	1855810..1856577 (+)	768	WP_126408103.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 396 a.a.
• Molecular weight: 41664.61 Da
• Isoelectric Point: 9.4264

>NTDB_id=1120287 EL087_RS09215 WP_126408101.1 1854565..1855755(+) (htrA) [Streptococcus milleri strain NCTC11169]
MKNSSNFTKKLLLLFMVLAIGFIGGLLGNLTSSKLSTNSSTTTKVNQVTTAYKNTNSTTQAVSKVKDAVVSVITYANNNS
QNSVFGNDDSNNNNDNSQQVASEGSGVIYKKDGKYAYLVTNTHVISGAKKVDIRLADGNKVPGEIVGSDTYSDISVVRIS
ADKVKSVAEFGDSSKLTVGETAIAIGSPLGSNYANTVTQGIISSLNRNVSLKSEDGQTISTQAIQTDTAINPGNSGGPLV
NIQGQVIGITSSKIASNGGTSVEGLGFAIPSNDVINIINQLEANGTVTRPALGIQMIDITNLSSSDLSRLKLPSKITSGV
VVRSAQSGMPAEGKLQKYDVITKVDDKEISSTSDLQSALYKHSIGDNIKITFYRDGKETTNTIKLTKSTKDLDSNN

Nucleotide

• Length: 1191 bp

>NTDB_id=1120287 EL087_RS09215 WP_126408101.1 1854565..1855755(+) (htrA) [Streptococcus milleri strain NCTC11169]
ATGAAAAACTCTTCAAATTTCACAAAAAAATTGTTATTGCTTTTCATGGTCTTAGCTATAGGTTTTATTGGTGGTTTACT
TGGAAACTTAACTTCATCTAAATTATCAACAAATAGCTCTACAACGACTAAAGTTAATCAAGTTACTACTGCTTATAAAA
ATACAAATTCCACAACACAAGCTGTGAGTAAAGTAAAAGATGCTGTTGTATCCGTTATTACCTATGCTAATAATAATTCA
CAAAACAGTGTGTTTGGAAATGATGATTCAAATAATAACAATGATAATTCTCAACAAGTAGCTAGCGAAGGATCTGGAGT
TATTTATAAAAAAGATGGAAAATACGCTTACTTAGTAACCAATACCCACGTTATCAGTGGTGCTAAAAAAGTTGACATTC
GTTTAGCAGATGGTAATAAAGTTCCTGGAGAAATTGTAGGGTCAGATACTTATTCTGATATCTCCGTTGTTCGCATTAGT
GCTGATAAAGTAAAATCAGTTGCTGAATTTGGAGATTCTAGCAAATTGACTGTTGGTGAGACAGCTATTGCGATTGGAAG
TCCGCTCGGATCAAATTACGCTAACACTGTGACGCAAGGAATTATTTCTAGTTTAAATCGTAATGTTTCTCTAAAATCTG
AAGACGGACAAACGATTTCAACACAAGCTATTCAAACAGACACAGCTATCAACCCAGGGAACTCTGGTGGACCACTTGTG
AATATCCAAGGGCAAGTAATTGGTATTACTTCAAGTAAAATAGCTAGCAACGGCGGAACTTCGGTTGAAGGATTAGGATT
TGCTATTCCATCTAATGATGTTATAAACATTATTAACCAGTTAGAAGCAAATGGAACTGTTACACGACCAGCTCTAGGAA
TCCAAATGATTGACATCACTAATCTGTCTAGTTCAGATCTATCACGCTTAAAACTTCCATCAAAAATAACTAGTGGAGTT
GTCGTGCGTTCAGCTCAATCTGGAATGCCAGCTGAAGGAAAACTTCAAAAATATGATGTGATTACAAAAGTAGATGATAA
AGAAATTTCTTCAACAAGTGATTTACAATCTGCTTTATACAAACATTCAATTGGCGACAACATAAAAATCACTTTCTATC
GTGATGGAAAAGAAACTACTAATACCATTAAGCTTACAAAATCTACAAAAGATTTAGATTCAAATAATTGA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (104-249)

• PDZ domain (PDZ_2) (290-385)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	75.312	100	0.763
htrA	Streptococcus mitis NCTC 12261	72.292	100	0.725
htrA	Streptococcus pneumoniae Rx1	72.04	100	0.722
htrA	Streptococcus pneumoniae D39	72.04	100	0.722
htrA	Streptococcus pneumoniae R6	72.04	100	0.722
htrA	Streptococcus pneumoniae TIGR4	72.04	100	0.722
htrA	Streptococcus mutans UA159	55.471	99.242	0.551