Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   EL087_RS09195 Genome accession   NZ_LR134288
Coordinates   1852122..1853444 (-) Length   440 a.a.
NCBI ID   WP_218969867.1    Uniprot ID   -
Organism   Streptococcus milleri strain NCTC11169     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1847122..1858444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL087_RS09170 (NCTC11169_01887) - 1847427..1850003 (+) 2577 WP_126408097.1 YfhO family protein -
  EL087_RS09175 (NCTC11169_01888) - 1850047..1850904 (-) 858 WP_126408099.1 transposase -
  EL087_RS09190 (NCTC11169_01891) comE 1851373..1852122 (-) 750 WP_003029521.1 competence system response regulator transcription factor ComE Regulator
  EL087_RS09195 (NCTC11169_01892) comD/comD2 1852122..1853444 (-) 1323 WP_218969867.1 sensor histidine kinase Regulator
  EL087_RS09200 (NCTC11169_01893) - 1853465..1853611 (-) 147 WP_003029519.1 bacteriocin -
  EL087_RS09210 (NCTC11169_01895) rlmH 1853893..1854372 (-) 480 WP_049533214.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  EL087_RS09215 (NCTC11169_01896) htrA 1854565..1855755 (+) 1191 WP_126408101.1 S1C family serine protease Regulator
  EL087_RS09220 (NCTC11169_01897) spo0J 1855810..1856577 (+) 768 WP_126408103.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 51962.71 Da        Isoelectric Point: 8.9107

>NTDB_id=1120286 EL087_RS09195 WP_218969867.1 1852122..1853444(-) (comD/comD2) [Streptococcus milleri strain NCTC11169]
MKIEFIHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFLTDFTTLIHYSIRYMMFFIQPLFFYLYFFKVKKVK
KHLSVFLALFLSLAVSSSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKADFKENIVQL
NFYLLFIHFLLNLSHWLSNMKNLNSFSSMIATICFLMFMSTLFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVNLYN
EIRGFRHDYGGMLASFQSAIHTGNIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKARDYNIELT
FEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGSAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGEG
RGLGLSNIKEIINNYEGIILDTKIEDEYFTQVMRVRKEGL

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=1120286 EL087_RS09195 WP_218969867.1 1852122..1853444(-) (comD/comD2) [Streptococcus milleri strain NCTC11169]
GTGAAAATAGAATTTATACATTGGATTATTTTCTCAATTATAGAAGCTGTTTCTGTTGTATACTGCTATAAGAAAATAAG
TAGAGTGAATAAAGTGAATATTCACTTTACTTTGTTGTGTTTAGGAATTGTATTTTTAACTGATTTCACTACTTTAATAC
ATTATTCCATTAGATATATGATGTTTTTTATTCAACCATTATTTTTTTATTTATATTTTTTTAAAGTAAAAAAAGTTAAA
AAACATCTTTCTGTATTTTTAGCACTATTTTTATCTTTAGCTGTGTCAAGTTCTGAAACCTTCTTTTCAGTCATTATTTC
TTCTGTTACAGGTGATAAGTTTGTTGATAGATACTGGGGATTGTTCTATATTTTTATCAATATCATTTCTTTAGTTTTTA
TTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGCGGATTTTAAAGAGAATATTGTGCAGTTA
AACTTTTATCTCTTATTTATTCATTTTTTATTAAATTTGTCGCATTGGCTTAGTAATATGAAAAATTTAAATAGTTTTTC
TAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAACTTTATTCTACTTACAATCTATTCGCGAAAAGTATGAAA
AAGAAGAACAAATTAAACAGAAAGAACGAGAACAACTACAATTACAAAAATATACAGATGAAATTGTTAATCTGTATAAT
GAAATTCGAGGTTTTCGTCACGATTATGGTGGGATGTTGGCAAGTTTTCAATCAGCTATTCATACAGGTAATATAAAAGA
AGTGGAGCGAATCTATCAGGAGGTTCTCGTAAATGCTAATTTACAGCTTCGTTCTGATAAATATACGTATTTTGATTTAA
ATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACGCAAACATTGTTTAAGGCACGAGATTACAATATAGAATTAACA
TTTGAAGTAAAAGATTTTGTTAAACCTTTGCCAATTAAATTGTTAGATTTGGTTAGAATGACAAGTGTTCTTTTGAATAA
TGCCATAGAAGGATCAGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTGGTGGATTTAGATACAGAAACAATCTTAG
TCATTCAAAATTCACGTAAGAAAAGACCGCTAGATTTAGAAGAGATTTACCAAACTGATTTTTCAACAAAGGGTGAAGGA
CGCGGTTTAGGCTTAAGCAATATCAAAGAAATTATTAACAACTATGAAGGAATTATCCTCGATACTAAAATTGAGGATGA
ATATTTTACACAAGTAATGAGAGTGCGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

54.072

100

0.543
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.338

99.545

0.541
  comD Streptococcus mitis SK321

47.704

89.091

0.425
  comD Streptococcus mitis NCTC 12261

48.936

85.455

0.418
  comD/comD2 Streptococcus pneumoniae TIGR4

48.67

85.455

0.416
  comD/comD1 Streptococcus pneumoniae Rx1

48.138

85.455

0.411
  comD/comD1 Streptococcus pneumoniae D39

48.138

85.455

0.411
  comD/comD1 Streptococcus pneumoniae R6

48.138

85.455

0.411

Multiple sequence alignment