Detailed information NTG1120122

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: EL070_RS08420
• Genome accession: NZ_LR134284
• Coordinates: 1578021..1578611 (-)
• Length: 196 a.a.
• NCBI ID: WP_002985850.1
• Uniprot ID: A0A9X8T4H8
• Organism: Streptococcus pyogenes strain NCTC8232
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1573021..1583611

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL070_RS08385 (NCTC8232_01686)	-	1573201..1573593 (-)	393	WP_002985833.1	DUF5684 domain-containing protein	-
EL070_RS08390 (NCTC8232_01687)	rsmI	1573620..1574483 (-)	864	WP_111705465.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
EL070_RS08395 (NCTC8232_01688)	yabA	1574488..1574811 (-)	324	WP_002985838.1	DNA replication initiation control protein YabA	-
EL070_RS08400 (NCTC8232_01689)	-	1575216..1575455 (-)	240	WP_011017422.1	hypothetical protein	-
EL070_RS08405 (NCTC8232_01690)	-	1575474..1576349 (-)	876	WP_126405172.1	DNA polymerase III subunit delta'	-
EL070_RS08410 (NCTC8232_01691)	tmk	1576367..1577002 (-)	636	WP_010921930.1	dTMP kinase	-
EL070_RS08415 (NCTC8232_01692)	-	1577251..1577526 (-)	276	WP_002985847.1	YlbG family protein	-
EL070_RS08420 (NCTC8232_01693)	clpP	1578021..1578611 (-)	591	WP_002985850.1	ATP-dependent Clp protease proteolytic subunit	Regulator
EL070_RS08430 (NCTC8232_01694)	upp	1578835..1579464 (-)	630	WP_002985854.1	uracil phosphoribosyltransferase	-
EL070_RS08435 (NCTC8232_01695)	-	1579632..1581266 (-)	1635	WP_063632594.1	polysaccharide biosynthesis protein	-
EL070_RS08440 (NCTC8232_01696)	-	1581354..1582799 (+)	1446	WP_011184212.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21648.88 Da
• Isoelectric Point: 5.2834

>NTDB_id=1120122 EL070_RS08420 WP_002985850.1 1578021..1578611(-) (clpP) [Streptococcus pyogenes strain NCTC8232]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRHRLEKILAQNAGK
TIKQIHKDAERDYWMSAEETLAYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=1120122 EL070_RS08420 WP_002985850.1 1578021..1578611(-) (clpP) [Streptococcus pyogenes strain NCTC8232]
ATGATTCCTGTTGTTATTGAACAAACTAGCCGTGGAGAACGTTCTTATGACATTTATTCACGTTTATTAAAAGACCGTAT
TATCATGTTAACAGGGCCTGTCGAAGACAACATGGCCAACTCTGTCATAGCGCAGCTCTTATTCCTTGACGCGCAAGACA
ACACTAAAGATATCTACCTATATGTCAACACACCAGGTGGCTCTGTCTCAGCAGGCTTGGCTATTGTCGATACCATGAAC
TTTATCAAGGCCGATGTGCAAACTATTGTCATGGGTATGGCAGCTTCTATGGGGACAGTCATTGCTTCATCAGGAACAAA
AGGCAAACGCTTTATGTTACCAAATGCAGAGTATATGATCCACCAGCCAATGGGTGGCACAGGCGGTGGCACGCAACAAA
CGGATATGGCTATCGCAGCAGAACATCTCTTAAAAACACGTCACCGTTTAGAAAAAATCTTAGCGCAAAATGCTGGAAAA
ACGATTAAACAAATCCATAAAGATGCTGAGCGTGATTATTGGATGAGTGCTGAAGAAACCTTGGCTTACGGTTTCATTGA
TGAAATCATGGAAAATAACGAACTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes MGAS315	100	100	1
clpP	Streptococcus pyogenes JRS4	100	100	1
clpP	Streptococcus mutans UA159	90.816	100	0.908
clpP	Streptococcus pneumoniae Rx1	90.769	99.49	0.903
clpP	Streptococcus pneumoniae D39	90.769	99.49	0.903
clpP	Streptococcus pneumoniae R6	90.769	99.49	0.903
clpP	Streptococcus pneumoniae TIGR4	90.769	99.49	0.903
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	86.224	100	0.862
clpP	Lactococcus lactis subsp. cremoris KW2	85.714	100	0.857
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	56.995	98.469	0.561