Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   EL086_RS05890 Genome accession   NZ_LR134274
Coordinates   1211001..1211840 (-) Length   279 a.a.
NCBI ID   WP_038676132.1    Uniprot ID   -
Organism   Streptococcus salivarius strain NCTC8618     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1206001..1216840
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL086_RS05870 (NCTC8618_03598) - 1206461..1207111 (-) 651 WP_038676126.1 nisG -
  EL086_RS05875 (NCTC8618_03599) - 1207098..1207826 (-) 729 WP_038676128.1 lantibiotic ABC transporter permease -
  EL086_RS05880 (NCTC8618_03600) - 1207831..1208505 (-) 675 WP_038676130.1 ABC transporter ATP-binding protein -
  EL086_RS05885 (NCTC8618_03601) topA 1208689..1210833 (-) 2145 WP_014633069.1 type I DNA topoisomerase -
  EL086_RS05890 (NCTC8618_03602) dprA 1211001..1211840 (-) 840 WP_038676132.1 DNA-processing protein DprA Machinery gene
  EL086_RS05895 (NCTC8618_03603) - 1211907..1212827 (-) 921 WP_038676134.1 ROK family protein -
  EL086_RS05900 - 1212834..1213603 (-) 770 Protein_1119 ribonuclease HII -
  EL086_RS05905 (NCTC8618_03606) ylqF 1213590..1214444 (-) 855 WP_038676138.1 ribosome biogenesis GTPase YlqF -
  EL086_RS05910 (NCTC8618_03607) - 1214573..1215262 (-) 690 WP_013990509.1 XRE family transcriptional regulator -
  EL086_RS05915 (NCTC8618_03608) - 1215357..1215872 (-) 516 WP_013990508.1 transcription repressor NadR -
  EL086_RS05920 (NCTC8618_03609) - 1215895..1216422 (-) 528 WP_002883896.1 ECF transporter S component -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 31263.22 Da        Isoelectric Point: 8.6585

>NTDB_id=1119823 EL086_RS05890 WP_038676132.1 1211001..1211840(-) (dprA) [Streptococcus salivarius strain NCTC8618]
MNNFELFKLKAAGLTNLNIINILDYQKTQDRKLSLRDMAVVSKSKNAVLFMEKYKSLDIKQLKEQFERFPTLSIFDKEYP
IELKHAYNPPVLLYYQGNLDLLSKPKLAVVGARKCSETGKQSVRKIVSELGNHFTIVSGLARGIDTCAHMEALKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPGEQPLKYHFPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDILSEFS

Nucleotide


Download         Length: 840 bp        

>NTDB_id=1119823 EL086_RS05890 WP_038676132.1 1211001..1211840(-) (dprA) [Streptococcus salivarius strain NCTC8618]
ATGAATAATTTTGAACTTTTTAAACTTAAAGCCGCTGGGTTGACGAATTTGAATATCATAAATATTTTGGACTACCAAAA
GACTCAAGATAGAAAATTGAGTTTACGTGATATGGCAGTGGTATCCAAGTCTAAAAATGCCGTTCTTTTTATGGAAAAGT
ATAAGAGTTTAGATATTAAGCAACTCAAAGAACAGTTTGAACGTTTTCCTACGTTATCGATTTTTGATAAAGAATATCCC
ATTGAGCTGAAGCATGCCTATAATCCTCCTGTTCTCCTTTATTATCAGGGGAATCTTGATTTACTGAGTAAACCAAAGCT
AGCAGTTGTTGGGGCAAGAAAGTGTTCTGAAACAGGCAAACAGTCTGTCCGTAAAATTGTTAGTGAACTTGGGAATCACT
TTACTATTGTGAGTGGATTGGCGCGTGGGATTGATACTTGTGCGCATATGGAGGCCTTGAAAAATAAGGGAAACACTATT
GCAGTTATCGGGACTGGACTTGATGTTTATTATCCTAAAGAAAATAAAGCTTTGCAGGACTATATGGCTAAAAATCATTT
AGTTCTTACTGAATATGGACCGGGTGAGCAGCCTCTCAAGTACCACTTTCCTGAACGCAATCGGATTATTTCTGGATTGT
GTCAAGGAGTTATGGTTGTAGAAGCTAAGCTTCGCTCAGGAAGTCTGATTACTTGTGAGCGTGCCATGGAAGAAGGTAGA
GATGTTTTTGCTATTCCAGGAAATATTTTAGATGGAAAGTCAGATGGATGTCATCACCTAATTCAGGAGGGTGCAAAGTG
CATCACGACAGGGTTTGACATTCTTTCAGAGTTTTCTTGA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)

DNA recombination-mediator protein A (DNA_processg_A)

(71-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

71.685

100

0.717
  dprA/cilB/dalA Streptococcus mitis SK321

62.95

99.642

0.627
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

62.95

99.642

0.627
  dprA/cilB/dalA Streptococcus pneumoniae D39

62.95

99.642

0.627
  dprA/cilB/dalA Streptococcus pneumoniae R6

62.95

99.642

0.627
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

62.95

99.642

0.627
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

62.59

99.642

0.624
  dprA Lactococcus lactis subsp. cremoris KW2

59.712

99.642

0.595
  dprA Acinetobacter baylyi ADP1

41.085

92.473

0.38
  dprA Latilactobacillus sakei subsp. sakei 23K

40.154

92.832

0.373
  dprA Bacillus subtilis subsp. subtilis str. 168

48.095

75.269

0.362

Multiple sequence alignment