Detailed information NTG1119820

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: EL086_RS04990
• Genome accession: NZ_LR134274
• Coordinates: 1008538..1009245 (+)
• Length: 235 a.a.
• NCBI ID: WP_002884978.1
• Uniprot ID: A0AB33ZBK5
• Organism: Streptococcus salivarius strain NCTC8618
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1003538..1014245

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL086_RS04965 (NCTC8618_03415)	-	1004297..1005064 (-)	768	WP_060775856.1	amino acid ABC transporter ATP-binding protein	-
EL086_RS04970 (NCTC8618_03416)	-	1005250..1005900 (-)	651	WP_002886253.1	amino acid ABC transporter permease	-
EL086_RS04975 (NCTC8618_03417)	-	1005912..1006610 (-)	699	WP_002886251.1	amino acid ABC transporter permease	-
EL086_RS04980 (NCTC8618_03418)	-	1006628..1007461 (-)	834	WP_037611665.1	transporter substrate-binding domain-containing protein	-
EL086_RS04985 (NCTC8618_03419)	-	1007471..1008238 (-)	768	WP_038675884.1	amino acid ABC transporter ATP-binding protein	-
EL086_RS04990 (NCTC8618_03420)	vicR	1008538..1009245 (+)	708	WP_002884978.1	response regulator YycF	Regulator
EL086_RS04995 (NCTC8618_03421)	vicK	1009238..1010581 (+)	1344	WP_038675887.1	cell wall metabolism sensor histidine kinase VicK	Regulator
EL086_RS05000 (NCTC8618_03422)	vicX	1010587..1011396 (+)	810	WP_126405093.1	MBL fold metallo-hydrolase	Regulator
EL086_RS05005 (NCTC8618_03423)	-	1011455..1011814 (+)	360	WP_037611660.1	YbaN family protein	-
EL086_RS05010 (NCTC8618_03424)	-	1011866..1013080 (-)	1215	WP_038675892.1	aminoacyltransferase	-
EL086_RS05015 (NCTC8618_03425)	yidA	1013082..1013891 (-)	810	WP_002890845.1	sugar-phosphatase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27045.90 Da
• Isoelectric Point: 4.8387

>NTDB_id=1119820 EL086_RS04990 WP_002884978.1 1008538..1009245(+) (vicR) [Streptococcus salivarius strain NCTC8618]
MKKILVVDDERPISDIIKFNLTKEGYEVVTAFDGREALEQFEAEKPDLVILDLMLPELDGLEVAKEIRKTSHTPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTETIETAAEESSNSGKQEISIGELIIVPDAFVAKKRGNEVEL
THREFELLFHLATHMGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKNYD

Nucleotide

• Length: 708 bp

>NTDB_id=1119820 EL086_RS04990 WP_002884978.1 1008538..1009245(+) (vicR) [Streptococcus salivarius strain NCTC8618]
ATGAAAAAAATTCTAGTTGTTGATGACGAAAGACCGATTTCGGACATCATCAAGTTTAACCTGACAAAAGAAGGTTATGA
AGTGGTTACGGCTTTTGATGGTCGTGAAGCTTTGGAGCAGTTTGAAGCTGAAAAGCCAGACTTGGTCATCCTGGACTTGA
TGTTGCCTGAACTAGATGGTTTAGAAGTTGCTAAGGAAATTCGAAAGACAAGTCATACACCAATTATCATGCTCTCCGCT
AAGGATAGCGAGTTTGATAAGGTTATCGGACTAGAAATTGGGGCGGACGACTATGTGACGAAACCATTTTCTAATCGTGA
ATTGTTGGCACGTATCAAAGCTCACCTGCGTCGTACAGAGACTATTGAAACAGCAGCAGAAGAAAGCTCTAACTCTGGCA
AGCAGGAGATTTCAATTGGTGAGTTGATTATTGTTCCAGATGCATTTGTTGCTAAAAAACGTGGAAATGAAGTTGAGCTC
ACACACCGTGAATTTGAGTTGCTTTTCCATTTGGCAACTCATATGGGACAAGTGATGACGCGTGAGCATTTGCTTGAAAC
TGTTTGGGGCTATGACTATTTTGGTGATGTTCGTACGGTTGACGTAACCATTCGTCGTCTCCGTGAAAAAATTGAAGATA
CACCTAGTCGTCCTGAATATATTTTGACGCGTCGTGGTGTTGGTTATTATATGAAGAATTATGACTAG

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (4-113)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	85.532	100	0.855
micA	Streptococcus pneumoniae Cp1015	80.687	99.149	0.8
covR	Streptococcus salivarius strain HSISS4	44.872	99.574	0.447
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
scnR	Streptococcus mutans UA159	38.559	100	0.387