Detailed information NTG1119731

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: EL077_RS00280
• Genome accession: NZ_LR134273
• Coordinates: 47755..48669 (+)
• Length: 304 a.a.
• NCBI ID: WP_111677624.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. equi strain NCTC12091
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 42755..53669

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL077_RS00260 (NCTC12091_00052)	purE	43918..44406 (+)	489	WP_037582413.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
EL077_RS00265 (NCTC12091_00053)	purK	44393..45484 (+)	1092	WP_037582412.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
EL077_RS00270 (NCTC12091_00054)	-	45494..45718 (+)	225	WP_037582407.1	hypothetical protein	-
EL077_RS09820	-	45743..45847 (+)	105	WP_370444775.1	hypothetical protein	-
EL077_RS00275 (NCTC12091_00055)	purB	46164..47456 (+)	1293	WP_037582405.1	adenylosuccinate lyase	-
EL077_RS00280 (NCTC12091_00056)	comR	47755..48669 (+)	915	WP_111677624.1	helix-turn-helix domain-containing protein	Regulator
EL077_RS10045 (NCTC12091_00057)	comS	48752..48850 (+)	99	WP_200831644.1	quorum-sensing system DWW-type pheromone	Regulator
EL077_RS00285 (NCTC12091_00058)	ruvB	48884..49885 (+)	1002	WP_111677625.1	Holliday junction branch migration DNA helicase RuvB	-
EL077_RS00290 (NCTC12091_00059)	-	50178..50636 (+)	459	WP_126436186.1	low molecular weight protein-tyrosine-phosphatase	-
EL077_RS00295 (NCTC12091_00060)	-	50642..51043 (+)	402	WP_037582396.1	membrane protein	-
EL077_RS00300 (NCTC12091_00061)	-	51040..52821 (+)	1782	WP_126436188.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35851.33 Da
• Isoelectric Point: 4.4139

>NTDB_id=1119731 EL077_RS00280 WP_111677624.1 47755..48669(+) (comR) [Streptococcus equi subsp. equi strain NCTC12091]
MLDNFGEKVRDLRYQKKITREDLCGDESELSIRQLARIELGQSIPSLSKVVFIAKALDVSVGFLTDGEDLELPKRYKELK
YLILRTPTYMDDDKLKLREEQFDEIFEDYYDQLPEEEKLVVDCLQSIMDTLLTENINFGVGLLQEYFEQTKSKTQFREND
LILIELYLAYLDIVGMNGEYSDKGFYDSLLDILLNQFEHFELEELFIVNKIAIGISSLSIKNNKLEILEKVIVLSQKIIL
KTQDFNRMPILNLIEWKYALMKKKDVEMAEKCYDKACLFAQLTGDQYLEKKLREEWDKDIKQYQ

Nucleotide

• Length: 915 bp

>NTDB_id=1119731 EL077_RS00280 WP_111677624.1 47755..48669(+) (comR) [Streptococcus equi subsp. equi strain NCTC12091]
ATGTTAGACAATTTTGGTGAAAAGGTGAGAGACCTTCGGTATCAGAAAAAAATTACCAGAGAGGATTTATGTGGAGATGA
GTCAGAATTATCCATTCGTCAATTGGCACGAATAGAACTGGGCCAATCGATTCCCAGCCTATCAAAGGTGGTTTTTATTG
CTAAGGCTTTGGACGTTAGTGTCGGCTTTTTGACAGACGGAGAGGATTTGGAGCTACCGAAGCGCTATAAGGAGCTTAAA
TATTTGATTTTAAGAACACCGACCTATATGGACGATGACAAATTAAAGCTACGTGAAGAGCAATTTGACGAAATTTTTGA
AGATTATTATGATCAGCTGCCAGAGGAAGAAAAGCTTGTGGTGGACTGCTTGCAGTCCATAATGGATACGTTATTAACTG
AGAATATCAATTTTGGAGTTGGGTTATTACAGGAATACTTTGAACAGACAAAAAGCAAGACTCAATTTAGAGAGAATGAC
CTTATTCTTATTGAGCTGTATTTAGCGTATCTGGATATTGTGGGAATGAATGGAGAGTATTCAGATAAAGGATTCTATGA
TTCTTTATTAGACATTTTGTTAAATCAGTTTGAACATTTTGAATTAGAGGAATTATTTATCGTCAATAAAATAGCTATAG
GGATTTCCTCGTTGAGCATCAAAAACAATAAGCTGGAGATTCTTGAGAAGGTTATTGTGCTTAGTCAAAAAATTATTCTC
AAGACTCAGGATTTTAATAGAATGCCTATCTTAAATTTGATAGAGTGGAAATACGCTTTAATGAAGAAAAAAGACGTAGA
AATGGCAGAAAAATGTTATGATAAGGCATGCCTGTTTGCTCAATTAACAGGAGATCAGTATTTAGAAAAGAAATTAAGAG
AAGAATGGGATAAAGATATAAAACAATATCAATAG

Domains

Predicted by InterproScan.

• ComR tetratricopeptide (ComR_TPR) (73-296)

• Helix-turn-helix domain (HTH_19) (6-69)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS8232	74.917	99.671	0.747
comR	Streptococcus pyogenes MGAS315	54.485	99.013	0.539
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	52.069	95.395	0.497
comR	Streptococcus mutans UA159	48.829	98.355	0.48
comR	Streptococcus suis P1/7	38.591	98.026	0.378
comR	Streptococcus suis 05ZYH33	38.644	97.039	0.375
comR	Streptococcus suis D9	37.037	97.697	0.362