Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   EL071_RS02400 Genome accession   NZ_LR134265
Coordinates   464806..465558 (-) Length   250 a.a.
NCBI ID   WP_115356551.1    Uniprot ID   A0AB38VKP2
Organism   Streptococcus agalactiae strain NCTC8184     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 459806..470558
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL071_RS02375 (NCTC8184_00456) - 460675..461838 (-) 1164 WP_129544850.1 ABC transporter permease subunit -
  EL071_RS02380 (NCTC8184_00457) - 461844..462691 (-) 848 Protein_453 ABC transporter ATP-binding protein -
  EL071_RS02385 - 462760..462933 (-) 174 WP_115356553.1 transcriptional regulator -
  EL071_RS02390 (NCTC8184_00458) - 463222..463386 (+) 165 Protein_455 cysteine peptidase family C39 domain-containing protein -
  EL071_RS02395 (NCTC8184_00459) - 463475..464809 (-) 1335 WP_115356552.1 GHKL domain-containing protein -
  EL071_RS02400 (NCTC8184_00460) comE/blpR 464806..465558 (-) 753 WP_115356551.1 LytTR family DNA-binding domain-containing protein Regulator
  EL071_RS02410 (NCTC8184_00461) - 465774..466589 (-) 816 WP_001029866.1 endonuclease/exonuclease/phosphatase family protein -
  EL071_RS02415 (NCTC8184_00462) - 466643..468826 (-) 2184 WP_115356549.1 PTS transporter subunit IIBC -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 29442.03 Da        Isoelectric Point: 8.4441

>NTDB_id=1119495 EL071_RS02400 WP_115356551.1 464806..465558(-) (comE/blpR) [Streptococcus agalactiae strain NCTC8184]
MNIFILEDNFIQQARLERIIEEVKIRRSIHSKMVNTFEKPVQLLESICEKGMHNLYFLDIEIKNDEQRGLEVAKQIRQID
TYAQIVFVTTHSELMPLTFRYQVSALDYIDKGLSQEAFSRRIEEVLLYANNACSKNLLEDSFYFKSRYSQVQVPFNDILY
IETSLRSHRVVLYTAKDRMEFTATLGDILKQEPRLFQCHRSFLVNPLNIFKVDRSNKLIYLKNGSNCLISRNKIKDIMVV
IEESQRGRGI

Nucleotide


Download         Length: 753 bp        

>NTDB_id=1119495 EL071_RS02400 WP_115356551.1 464806..465558(-) (comE/blpR) [Streptococcus agalactiae strain NCTC8184]
GTGAATATTTTTATTTTAGAGGATAATTTTATTCAACAGGCACGTTTAGAGAGAATAATTGAGGAAGTTAAAATTAGGAG
AAGTATACACAGTAAAATGGTAAATACCTTTGAAAAACCAGTTCAATTATTGGAATCAATCTGTGAAAAAGGTATGCATA
ATTTATATTTCTTAGACATTGAAATAAAAAATGATGAGCAGAGGGGCTTAGAGGTCGCAAAACAAATTAGACAAATTGAT
ACTTATGCTCAGATTGTTTTTGTTACAACTCATTCGGAATTAATGCCTTTAACCTTTCGTTATCAGGTATCAGCTTTAGA
CTATATCGATAAAGGACTTTCACAGGAAGCATTTAGCAGAAGGATTGAAGAAGTTTTACTATATGCTAATAATGCTTGCA
GTAAAAACTTACTAGAAGATTCTTTTTATTTTAAATCACGCTATAGTCAAGTACAAGTACCTTTTAACGATATCCTTTAT
ATAGAAACGTCATTAAGGTCACATAGAGTTGTCCTTTATACTGCAAAAGACAGAATGGAATTCACAGCCACTTTGGGGGA
TATTTTAAAACAAGAACCTAGGCTCTTTCAATGTCATCGCTCTTTTTTAGTAAATCCCTTGAATATTTTTAAAGTGGATA
GGTCAAATAAACTAATCTATTTAAAAAATGGTTCGAATTGTTTGATTTCTCGTAATAAAATAAAAGATATTATGGTAGTA
ATAGAGGAAAGTCAAAGAGGTAGAGGAATATGA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-238)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.209

99.6

0.52
  comE/comE1 Streptococcus equinus JB1

42.259

95.6

0.404
  comE Streptococcus pneumoniae D39

38

100

0.38
  comE Streptococcus pneumoniae R6

38

100

0.38
  comE Streptococcus pneumoniae TIGR4

38

100

0.38
  comE Streptococcus mitis SK321

38

100

0.38
  comE Streptococcus mitis NCTC 12261

38

100

0.38
  comE Streptococcus pneumoniae Rx1

38

100

0.38
  comE Streptococcus infantis strain Atu-4

36.4

100

0.364

Multiple sequence alignment