Detailed information NTG1118946

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: EL020_RS03025
• Genome accession: NZ_LR134203
• Coordinates: 600760..602010 (+)
• Length: 416 a.a.
• NCBI ID: WP_020917669.1
• Uniprot ID: A0AB33APT2
• Organism: Streptococcus lutetiensis strain NCTC11436
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 595760..607010

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL020_RS03000	-	597877..599228 (+)	1352	WP_126402401.1	IS3 family transposase	-
EL020_RS03020 (NCTC11436_00631)	rlmH	600066..600545 (-)	480	WP_020917668.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
EL020_RS03025 (NCTC11436_00632)	htrA	600760..602010 (+)	1251	WP_020917669.1	S1C family serine protease	Regulator
EL020_RS03030 (NCTC11436_00633)	spo0J	602078..602860 (+)	783	WP_020917670.1	ParB/RepB/Spo0J family partition protein	Regulator
EL020_RS03035 (NCTC11436_00634)	dnaA	603064..604419 (+)	1356	WP_020915951.1	chromosomal replication initiator protein DnaA	-
EL020_RS03040 (NCTC11436_00635)	dnaN	604578..605714 (+)	1137	WP_020915952.1	DNA polymerase III subunit beta	-
EL020_RS03045	-	605845..606635 (+)	791	Protein_615	diacylglycerol/lipid kinase family protein	-
EL020_RS03050 (NCTC11436_00639)	-	606646..606837 (+)	192	WP_020915953.1	DUF951 domain-containing protein	-

Sequence

Protein

• Length: 416 a.a.
• Molecular weight: 43306.51 Da
• Isoelectric Point: 4.7284

>NTDB_id=1118946 EL020_RS03025 WP_020917669.1 600760..602010(+) (htrA) [Streptococcus lutetiensis strain NCTC11436]
MKKITFQKVNYKKILKPLSVILVGFIGGVAGTLLILNMAGISINNVSGSSTKTTTSKVSYSNTNDTTKAVEKVREAVVSV
INYQSNSSSNDLYMQMFGGNLDNNTNNGSDSDLSIASEGSGVIYKKDGNSAYVVTNNHVVDGASQIEIMLSDGTKVVGEL
VGTDTYSDIAVVKIASDKVTTVAEFANSDKITVGETAIAIGSPLGTDYANSVTQGIVSSLSRTVTMTNDDGETISTNAIQ
TDAAINPGNSGGALINIEGQVIGINSSKISSTSDSGSGNSVEGMGFAIPANDVVKIINQLEANGKVIRPALGITMANLSD
LSTTTISRLNIPTSVTSGIVVASVQSGMPAEGVLKKYDVITAIDDKDVSSITDLQSVLYGHSTGDSIKVTFYRGTDKKTE
TIKLTKTTQDLSSSNQ

Nucleotide

• Length: 1251 bp

>NTDB_id=1118946 EL020_RS03025 WP_020917669.1 600760..602010(+) (htrA) [Streptococcus lutetiensis strain NCTC11436]
GTGAAAAAAATAACATTTCAAAAAGTCAATTACAAAAAAATCCTTAAACCACTATCCGTTATTTTAGTTGGTTTCATCGG
AGGAGTTGCTGGGACCTTACTCATTTTGAATATGGCTGGCATCTCAATCAATAATGTTAGTGGTTCAAGTACAAAAACTA
CAACAAGTAAAGTAAGTTACTCAAATACTAATGATACGACAAAAGCTGTCGAAAAAGTGAGAGAAGCAGTCGTATCAGTC
ATCAATTATCAATCAAATAGCTCTTCAAATGATTTGTATATGCAAATGTTTGGTGGCAATTTAGACAATAACACTAATAA
TGGATCAGATAGTGATTTAAGTATCGCTAGTGAAGGTTCTGGGGTTATTTACAAAAAAGACGGCAATTCTGCTTATGTCG
TTACTAATAACCACGTTGTCGATGGTGCTAGTCAAATCGAAATCATGCTTTCTGACGGTACAAAAGTAGTCGGTGAATTA
GTCGGTACCGATACATACTCAGATATCGCCGTTGTCAAAATTGCTTCTGATAAAGTCACAACGGTAGCTGAATTTGCTAA
TTCAGATAAAATTACTGTTGGTGAAACAGCCATTGCTATTGGTAGCCCTCTAGGTACTGATTATGCTAACTCTGTGACAC
AAGGAATTGTCTCAAGTCTAAGCCGTACAGTTACAATGACTAACGACGATGGCGAAACAATTTCAACCAATGCTATCCAA
ACTGATGCCGCTATTAACCCAGGTAACTCTGGTGGTGCTTTGATTAACATTGAAGGACAAGTAATAGGTATTAATTCAAG
TAAAATCTCTTCTACCTCAGATTCTGGATCAGGTAATTCTGTAGAAGGTATGGGATTTGCTATTCCAGCTAATGATGTGG
TTAAAATTATTAATCAATTAGAAGCAAACGGAAAAGTTATTCGTCCAGCACTTGGTATCACAATGGCTAACCTAAGCGAT
TTATCAACAACAACAATCAGTCGCCTAAATATTCCAACTAGCGTCACATCTGGTATCGTCGTTGCTTCAGTTCAATCAGG
TATGCCTGCTGAAGGAGTACTTAAAAAATACGATGTAATCACAGCTATTGATGATAAAGATGTCTCTTCTATCACAGATC
TTCAAAGTGTTCTTTACGGTCATTCAACTGGAGATTCTATTAAAGTAACCTTCTATCGTGGTACTGACAAGAAAACAGAA
ACTATTAAACTAACGAAAACAACACAAGACCTCTCTTCATCAAATCAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (119-264)

• Peptidase family M50 (Peptidase_M50) (59-410)

• PDZ domain (PDZ_2) (309-404)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	64.838	96.394	0.625
htrA	Streptococcus gordonii str. Challis substr. CH1	60.741	97.356	0.591
htrA	Streptococcus mitis NCTC 12261	58.596	99.279	0.582
htrA	Streptococcus pneumoniae TIGR4	58.968	97.837	0.577
htrA	Streptococcus pneumoniae D39	58.968	97.837	0.577
htrA	Streptococcus pneumoniae Rx1	58.968	97.837	0.577
htrA	Streptococcus pneumoniae R6	58.968	97.837	0.577