Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   ELZ51_RS03435 Genome accession   NZ_LR134094
Coordinates   620944..621654 (+) Length   236 a.a.
NCBI ID   WP_003049952.1    Uniprot ID   A0A9X9SIG1
Organism   Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 615944..626654
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ51_RS03405 (NCTC4669_00714) - 615946..616941 (+) 996 WP_115252715.1 DUF3114 domain-containing protein -
  ELZ51_RS03410 (NCTC4669_00715) - 617116..617481 (+) 366 WP_003052735.1 IS3 family transposase -
  ELZ51_RS03415 (NCTC4669_00716) - 617715..618362 (-) 648 WP_003049948.1 amino acid ABC transporter permease -
  ELZ51_RS03420 (NCTC4669_00717) - 618377..619078 (-) 702 WP_126426133.1 amino acid ABC transporter permease -
  ELZ51_RS03425 (NCTC4669_00718) - 619092..619892 (-) 801 WP_126426135.1 transporter substrate-binding domain-containing protein -
  ELZ51_RS03430 (NCTC4669_00719) - 619892..620686 (-) 795 WP_003049951.1 amino acid ABC transporter ATP-binding protein -
  ELZ51_RS03435 (NCTC4669_00720) vicR 620944..621654 (+) 711 WP_003049952.1 response regulator YycF Regulator
  ELZ51_RS03440 (NCTC4669_00721) vicK 621647..622999 (+) 1353 WP_003049953.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ELZ51_RS03445 (NCTC4669_00722) vicX 623003..623812 (+) 810 WP_115246543.1 MBL fold metallo-hydrolase Regulator
  ELZ51_RS03450 (NCTC4669_00723) rnc 623911..624603 (+) 693 WP_115246542.1 ribonuclease III -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 27029.90 Da        Isoelectric Point: 4.9981

>NTDB_id=1118273 ELZ51_RS03435 WP_003049952.1 620944..621654(+) (vicR) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MKKILIVDDEKPISDIIKFNLTKEGYDIVTAFDGREAVTVFEDEKPDLIILDLMLPELDGLEVAKEIRKTSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTETIETAVAEENASSGSQELTIGNLQILPDAFVAKKHGKEVE
LTHREFELLHHLANHMGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMKSYD

Nucleotide


Download         Length: 711 bp        

>NTDB_id=1118273 ELZ51_RS03435 WP_003049952.1 620944..621654(+) (vicR) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGAAAAAAATACTGATTGTGGATGATGAGAAACCGATTTCTGACATTATTAAGTTTAACTTGACAAAAGAAGGTTATGA
CATTGTGACCGCTTTTGATGGCCGTGAAGCTGTTACCGTGTTTGAAGACGAAAAACCGGATTTAATTATTCTTGATTTGA
TGTTACCGGAATTGGACGGTCTTGAAGTGGCCAAAGAAATCCGTAAAACCAGTCATGTGCCGATTATTATGCTGTCGGCT
AAGGATAGTGAGTTTGACAAGGTCATTGGCCTTGAAATTGGAGCAGATGATTATGTTACCAAACCCTTTTCAAATCGTGA
ACTATTAGCGCGTGTCAAAGCTCATTTACGTCGAACAGAAACGATCGAAACAGCCGTAGCAGAGGAAAATGCTTCTTCAG
GTTCACAAGAGTTAACTATTGGTAATTTACAAATTTTACCAGATGCTTTTGTGGCTAAAAAACATGGCAAAGAAGTGGAA
TTAACCCATCGTGAATTTGAATTATTACACCACCTGGCCAATCATATGGGTCAAGTGATGACACGAGAGCACTTGCTTGA
GACGGTTTGGGGCTATGATTACTTTGGCGATGTCCGTACTGTGGACGTGACAGTTCGCCGCCTGCGTGAAAAAATTGAAG
ACACACCAAGCCGTCCCGAATATATTTTAACGAGACGCGGTGTTGGGTATTACATGAAATCTTATGACTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(156-231)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

90.254

100

0.903
  micA Streptococcus pneumoniae Cp1015

79.487

99.153

0.788
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.828

98.305

0.441
  covR Streptococcus salivarius strain HSISS4

44.397

98.305

0.436
  scnR Streptococcus mutans UA159

37.712

100

0.377

Multiple sequence alignment