Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   ELZ51_RS03440 Genome accession   NZ_LR134094
Coordinates   621647..622999 (+) Length   450 a.a.
NCBI ID   WP_003049953.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 616647..627999
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ51_RS03410 (NCTC4669_00715) - 617116..617481 (+) 366 WP_003052735.1 IS3 family transposase -
  ELZ51_RS03415 (NCTC4669_00716) - 617715..618362 (-) 648 WP_003049948.1 amino acid ABC transporter permease -
  ELZ51_RS03420 (NCTC4669_00717) - 618377..619078 (-) 702 WP_126426133.1 amino acid ABC transporter permease -
  ELZ51_RS03425 (NCTC4669_00718) - 619092..619892 (-) 801 WP_126426135.1 transporter substrate-binding domain-containing protein -
  ELZ51_RS03430 (NCTC4669_00719) - 619892..620686 (-) 795 WP_003049951.1 amino acid ABC transporter ATP-binding protein -
  ELZ51_RS03435 (NCTC4669_00720) vicR 620944..621654 (+) 711 WP_003049952.1 response regulator YycF Regulator
  ELZ51_RS03440 (NCTC4669_00721) vicK 621647..622999 (+) 1353 WP_003049953.1 cell wall metabolism sensor histidine kinase VicK Regulator
  ELZ51_RS03445 (NCTC4669_00722) vicX 623003..623812 (+) 810 WP_115246543.1 MBL fold metallo-hydrolase Regulator
  ELZ51_RS03450 (NCTC4669_00723) rnc 623911..624603 (+) 693 WP_115246542.1 ribonuclease III -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51476.02 Da        Isoelectric Point: 5.5557

>NTDB_id=1118274 ELZ51_RS03440 WP_003049953.1 621647..622999(+) (vicK) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKNRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEQALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1118274 ELZ51_RS03440 WP_003049953.1 621647..622999(+) (vicK) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGACTAGAGATATCATCGGGAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAATGAGAAGGCGGACATTGAATTGATGGAACTGGCAGATCAGTTAAATGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAATCGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGTTCTGGGAAAATCATCATGATTAACGAGACTGCCCGCAAGCAGCTTAATCTGACCAAGGAGCAGG
CTCTTGAAAAGAACATTACCGATTTGCTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTGACATTACGTTTACGTTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCCTCAAG
GAAGATATTGCCCCAAGTTTTATCAAAGTTTCTCTTGATGAAACCAATCGGATGATGCGAATGATTTCTGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTTGAGATGACCAATTTCACAGCTTTTATGACGTCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGATTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCAATTAAATACTCTCCTGA
TGGTGGGAAGATTACTGTTCGCATGAAAACAACAGACACGCAATTGATTATTTCCATCTCAGACCAAGGTTTAGGCATTC
CGAAGAAGGACCTGCCCCTTATTTTTGACCGTTTTTACCGAGTGGACAAGGCAAGAAGTCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATCTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-165)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631

Multiple sequence alignment