Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   EW022_RS04375 Genome accession   NZ_LR130240
Coordinates   849339..849527 (+) Length   62 a.a.
NCBI ID   WP_002993136.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain PS006 isolate PS006     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context

Location: 844339..854527
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EW022_RS04340 - 844731..844892 (+) 162 WP_002988795.1 hypothetical protein -
  EW022_RS04345 - 844895..845512 (+) 618 WP_011284840.1 hypothetical protein -
  EW022_RS04350 - 845523..845819 (+) 297 WP_002990012.1 hypothetical protein -
  EW022_RS04355 - 845816..846001 (+) 186 WP_011284839.1 holin -
  EW022_RS04360 - 846113..847447 (+) 1335 WP_011284838.1 GH25 family lysozyme -
  EW022_RS04365 speC 847523..848230 (-) 708 WP_002985327.1 streptococcal pyrogenic exotoxin SpeC -
  EW022_RS04370 mf2 848341..849099 (-) 759 WP_011184727.1 DNase Mf2 -
  EW022_RS04375 prx 849339..849527 (+) 189 WP_002993136.1 hypothetical protein Regulator
  EW022_RS04385 - 850118..850732 (+) 615 WP_002989607.1 TVP38/TMEM64 family protein -
  EW022_RS04390 - 850859..851644 (-) 786 WP_002984433.1 hypothetical protein -
  EW022_RS04395 - 851654..852352 (-) 699 WP_002984437.1 ABC transporter ATP-binding protein -
  EW022_RS04400 - 852352..852723 (-) 372 WP_002989617.1 GntR family transcriptional regulator -

Sequence

Protein


Download         Length: 62 a.a.        Molecular weight: 7239.28 Da        Isoelectric Point: 3.9944

>NTDB_id=1116735 EW022_RS04375 WP_002993136.1 849339..849527(+) (prx) [Streptococcus pyogenes strain PS006 isolate PS006]
MLTYDEFKQAIDNGYITGDTVIIVRKNGQIFDYVLPGEKVRPWEVVTEEVVEEVMVELDYIK

Nucleotide


Download         Length: 189 bp        

>NTDB_id=1116735 EW022_RS04375 WP_002993136.1 849339..849527(+) (prx) [Streptococcus pyogenes strain PS006 isolate PS006]
ATGCTAACATACGACGAATTTAAGCAAGCAATTGACAACGGATATATCACAGGAGACACAGTAATAATCGTGCGCAAAAA
CGGACAGATTTTTGATTATGTGTTGCCTGGTGAGAAAGTCAGACCATGGGAGGTTGTGACCGAGGAGGTAGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

85.484

100

0.855
  prx Streptococcus pyogenes MGAS8232

82.759

93.548

0.774
  prx Streptococcus pyogenes MGAS315

81.356

95.161

0.774
  prx Streptococcus pyogenes MGAS315

81.356

95.161

0.774
  prx Streptococcus pyogenes MGAS315

79.31

93.548

0.742
  prx Streptococcus pyogenes MGAS315

95.238

67.742

0.645
  prx Streptococcus pyogenes MGAS315

80.488

66.129

0.532

Multiple sequence alignment