Detailed information
Bioinformatically predicted
Overview
| Name | prx | Type | Regulator |
| Locus tag | EW025_RS05215 | Genome accession | NZ_LR130238 |
| Coordinates | 1007078..1007266 (-) | Length | 62 a.a. |
| NCBI ID | WP_011285559.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain HKU419 isolate HKU419 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Genomic Context
Location: 1002078..1012266
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EW025_RS05190 | - | 1003882..1004253 (+) | 372 | WP_049524979.1 | GntR family transcriptional regulator | - |
| EW025_RS05195 | - | 1004253..1004951 (+) | 699 | WP_002984437.1 | ABC transporter ATP-binding protein | - |
| EW025_RS05200 | - | 1004961..1005746 (+) | 786 | WP_010922378.1 | hypothetical protein | - |
| EW025_RS05205 | - | 1005873..1006487 (-) | 615 | WP_011285558.1 | TVP38/TMEM64 family protein | - |
| EW025_RS05215 | prx | 1007078..1007266 (-) | 189 | WP_011285559.1 | hypothetical protein | Regulator |
| EW025_RS05220 | speA | 1007486..1008241 (+) | 756 | WP_011285560.1 | streptococcal pyrogenic exotoxin SpeA | - |
| EW025_RS05225 | - | 1008363..1009022 (-) | 660 | WP_009880240.1 | hypothetical protein | - |
| EW025_RS05230 | - | 1009022..1009243 (-) | 222 | WP_009880241.1 | hypothetical protein | - |
| EW025_RS05235 | - | 1009253..1010026 (-) | 774 | WP_011054795.1 | hypothetical protein | - |
| EW025_RS05240 | - | 1010037..1010639 (-) | 603 | WP_011054796.1 | hypothetical protein | - |
| EW025_RS05245 | - | 1010651..1011415 (-) | 765 | WP_011285561.1 | CHAP domain-containing protein | - |
| EW025_RS05250 | - | 1011417..1011749 (-) | 333 | WP_011285562.1 | phage holin | - |
| EW025_RS05255 | - | 1011749..1012072 (-) | 324 | WP_015055952.1 | hypothetical protein | - |
| EW025_RS10410 | - | 1012086..1012208 (-) | 123 | WP_015055953.1 | hypothetical protein | - |
Sequence
Protein
Download Length: 62 a.a. Molecular weight: 7290.41 Da Isoelectric Point: 4.3313
>NTDB_id=1116618 EW025_RS05215 WP_011285559.1 1007078..1007266(-) (prx) [Streptococcus pyogenes strain HKU419 isolate HKU419]
MLYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPHEKVRDDEVVTVERVEEVMVELDYIK
MLYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPHEKVRDDEVVTVERVEEVMVELDYIK
Nucleotide
Download Length: 189 bp
>NTDB_id=1116618 EW025_RS05215 WP_011285559.1 1007078..1007266(-) (prx) [Streptococcus pyogenes strain HKU419 isolate HKU419]
ATGTTATATATAGATGAGTTTAAAGAAGCGATTGATAAGGGGTATATTTTAGGTGACACAGTAGCGATAGTGCGTAAAAA
CGGAAAGATATTTGATTATGTGTTACCACACGAAAAAGTGAGAGATGATGAAGTTGTGACGGTAGAGAGAGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA
ATGTTATATATAGATGAGTTTAAAGAAGCGATTGATAAGGGGTATATTTTAGGTGACACAGTAGCGATAGTGCGTAAAAA
CGGAAAGATATTTGATTATGTGTTACCACACGAAAAAGTGAGAGATGATGAAGTTGTGACGGTAGAGAGAGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS315 |
100 |
95.161 |
0.952 |
| prx | Streptococcus pyogenes MGAS315 |
79.032 |
100 |
0.79 |
| prx | Streptococcus pyogenes MGAS8232 |
76.271 |
95.161 |
0.726 |
| prx | Streptococcus pyogenes MGAS315 |
76.271 |
95.161 |
0.726 |
| prx | Streptococcus pyogenes MGAS315 |
74.576 |
95.161 |
0.71 |
| prx | Streptococcus pyogenes MGAS315 |
69.492 |
95.161 |
0.661 |
| prx | Streptococcus pyogenes MGAS315 |
82.927 |
66.129 |
0.548 |