Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   AT689_RS10075 Genome accession   NZ_LN831051
Coordinates   1898460..1899050 (-) Length   196 a.a.
NCBI ID   WP_000613479.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain NCTC7465     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1890424..1900985 1898460..1899050 within 0


Gene organization within MGE regions


Location: 1890424..1900985
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AT689_RS10030 (ERS445053_01965) ftsE 1890424..1891116 (-) 693 WP_000022267.1 cell division ATP-binding protein FtsE -
  AT689_RS10040 (ERS445053_01967) - 1892337..1892993 (-) 657 WP_000268677.1 CBS domain-containing protein -
  AT689_RS10045 (ERS445053_01968) - 1893301..1894011 (-) 711 WP_000062219.1 ABC transporter ATP-binding protein -
  AT689_RS10050 (ERS445053_01969) - 1894011..1894775 (-) 765 WP_001186003.1 ABC transporter ATP-binding protein -
  AT689_RS10055 (ERS445053_01970) - 1894775..1895731 (-) 957 WP_000662293.1 branched-chain amino acid ABC transporter permease -
  AT689_RS10060 (ERS445053_01971) - 1895735..1896604 (-) 870 WP_000941426.1 branched-chain amino acid ABC transporter permease -
  AT689_RS10065 (ERS445053_01972) - 1896872..1898032 (-) 1161 WP_000726147.1 ABC transporter substrate-binding protein -
  AT689_RS10070 (ERS445053_01973) - 1898133..1898381 (-) 249 WP_000462126.1 YlbG family protein -
  AT689_RS10075 (ERS445053_01974) clpP 1898460..1899050 (-) 591 WP_000613479.1 ATP-dependent Clp protease proteolytic subunit ClpP Regulator
  AT689_RS10080 (ERS445053_01975) upp 1899224..1899853 (-) 630 WP_000515974.1 uracil phosphoribosyltransferase -
  AT689_RS10085 (ERS445053_01976) - 1899942..1900409 (-) 468 WP_000136976.1 cytidine/deoxycytidylate deaminase family protein -
  AT689_RS10090 (ERS445053_01977) - 1900428..1900985 (-) 558 WP_000004139.1 TetR/AcrR family transcriptional regulator -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21383.37 Da        Isoelectric Point: 4.5912

>NTDB_id=1114411 AT689_RS10075 WP_000613479.1 1898460..1899050(-) (clpP) [Streptococcus pneumoniae strain NCTC7465]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMSIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAHETLEYGFIDEIMANNSLN

Nucleotide


Download         Length: 591 bp        

>NTDB_id=1114411 AT689_RS10075 WP_000613479.1 1898460..1899050(-) (clpP) [Streptococcus pneumoniae strain NCTC7465]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGGACTGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGAGTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCATGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

98.98

100

0.99
  clpP Streptococcus pneumoniae D39

98.98

100

0.99
  clpP Streptococcus pneumoniae R6

98.98

100

0.99
  clpP Streptococcus pneumoniae TIGR4

98.98

100

0.99
  clpP Streptococcus thermophilus LMG 18311

91.795

99.49

0.913
  clpP Streptococcus thermophilus LMD-9

91.795

99.49

0.913
  clpP Streptococcus pyogenes JRS4

90.256

99.49

0.898
  clpP Streptococcus pyogenes MGAS315

90.256

99.49

0.898
  clpP Streptococcus mutans UA159

85.204

100

0.852
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

84.615

99.49

0.842
  clpP Lactococcus lactis subsp. cremoris KW2

84.103

99.49

0.837
  clpP Bacillus subtilis subsp. subtilis str. 168

58.854

97.959

0.577
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.513

98.469

0.566

Multiple sequence alignment