Detailed information NTG1113975

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: LACPI_RS02465
• Genome accession: NZ_LN774769
• Coordinates: 490399..490995 (+)
• Length: 198 a.a.
• NCBI ID: WP_047914926.1
• Uniprot ID: A0A2A5RZA5
• Organism: Lactococcus piscium MKFS47
• Function: degradation of ComX; require for competence development (at the early growth phase); repress competence development (at the mid-logarithmic growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 485399..495995

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LACPI_RS02445 (LACPI_0469)	cysK	485815..486741 (-)	927	WP_047914923.1	cysteine synthase A	-
LACPI_RS02450 (LACPI_0470)	-	486846..487850 (+)	1005	WP_047914924.1	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	-
LACPI_RS02455 (LACPI_0471)	-	487959..488510 (-)	552	WP_082095390.1	MurR/RpiR family transcriptional regulator	-
LACPI_RS02460 (LACPI_0472)	-	488828..490255 (+)	1428	WP_419865933.1	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	-
LACPI_RS02465 (LACPI_0473)	clpP	490399..490995 (+)	597	WP_047914926.1	ATP-dependent Clp protease proteolytic subunit	Regulator
LACPI_RS02470 (LACPI_0474)	-	491206..492141 (+)	936	WP_047914927.1	IS30 family transposase	-
LACPI_RS02475 (LACPI_0475)	-	492141..492542 (+)	402	WP_231858771.1	hypothetical protein	-
LACPI_RS02480 (LACPI_0476)	-	492514..492837 (+)	324	WP_047914928.1	DUF2129 domain-containing protein	-
LACPI_RS02485 (LACPI_0477)	-	493488..493859 (+)	372	WP_157761110.1	hypothetical protein	-
LACPI_RS02490 (LACPI_0478)	-	493861..494271 (+)	411	WP_050702945.1	DUF4176 domain-containing protein	-
LACPI_RS02495 (LACPI_0479)	-	494353..494727 (+)	375	WP_143468137.1	hypothetical protein	-
LACPI_RS02500 (LACPI_0480)	-	494729..495904 (+)	1176	WP_050702947.1	hypothetical protein	-

Sequence

Protein

• Length: 198 a.a.
• Molecular weight: 21817.94 Da
• Isoelectric Point: 4.8819

>NTDB_id=1113975 LACPI_RS02465 WP_047914926.1 490399..490995(+) (clpP) [Lactococcus piscium MKFS47]
MVLIPTVIEQSSRGERAYDIYSRLLKDRIIMLTGEVEDNMANAVIAQLLFLDAQDATKDIYLYINSPGGSVSAGLAIVDT
MNFIKSDVQTIVMGVAASMGTIIASSGAKGKRFMLPNAEYLIHQPMGGTGGGTQQTDMQIVADHLSRTRKTLEKILAENS
GQTVNKIHKDAERDRWMSAEETLDYGFIDEIMNRNELK

Nucleotide

• Length: 597 bp

>NTDB_id=1113975 LACPI_RS02465 WP_047914926.1 490399..490995(+) (clpP) [Lactococcus piscium MKFS47]
ATGGTACTCATTCCTACAGTCATCGAACAATCAAGTCGCGGTGAGCGTGCTTACGATATTTATTCACGTCTTTTGAAAGA
CAGAATTATCATGCTTACAGGCGAAGTAGAAGACAATATGGCCAATGCTGTTATTGCGCAACTTTTGTTCTTAGATGCCC
AAGATGCGACTAAAGATATTTATTTATACATCAATTCACCAGGTGGATCAGTTTCGGCAGGTCTAGCTATTGTAGACACG
ATGAACTTTATCAAATCTGATGTACAGACGATTGTCATGGGTGTTGCGGCATCTATGGGCACGATCATCGCCTCATCTGG
TGCTAAGGGTAAACGCTTCATGCTACCAAATGCTGAATACCTCATCCACCAACCGATGGGTGGTACTGGTGGTGGTACAC
AACAAACAGATATGCAGATTGTTGCTGACCATTTATCACGTACACGTAAAACATTAGAAAAAATCTTGGCTGAAAATTCT
GGTCAAACAGTGAATAAAATTCATAAAGACGCTGAGCGTGATCGCTGGATGTCTGCTGAAGAAACCTTAGACTATGGGTT
TATTGACGAAATCATGAACCGTAACGAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-194)

3D structure

• AlphaFold DB: A0A2A5RZA5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus mutans UA159	85.204	98.99	0.843
clpP	Streptococcus pyogenes MGAS315	84.184	98.99	0.833
clpP	Streptococcus pyogenes JRS4	84.184	98.99	0.833
clpP	Streptococcus pneumoniae TIGR4	84.615	98.485	0.833
clpP	Streptococcus pneumoniae R6	84.615	98.485	0.833
clpP	Streptococcus pneumoniae Rx1	84.615	98.485	0.833
clpP	Streptococcus pneumoniae D39	84.615	98.485	0.833
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	83.673	98.99	0.828
clpP	Lactococcus lactis subsp. cremoris KW2	83.163	98.99	0.823
clpP	Streptococcus thermophilus LMD-9	82.653	98.99	0.818
clpP	Streptococcus thermophilus LMG 18311	82.653	98.99	0.818
clpP	Bacillus subtilis subsp. subtilis str. 168	57.576	100	0.576
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.763	97.98	0.576