Detailed information NTG1113399

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: HMPREF9318_RS10240
• Genome accession: NZ_KB373319
• Coordinates: 473107..473697 (+)
• Length: 196 a.a.
• NCBI ID: WP_006738636.1
• Uniprot ID: G5KCI9
• Organism: Streptococcus urinalis FB127-CNA-2
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 468107..478697

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9318_RS10215 (HMPREF9318_02042)	-	468256..469890 (+)	1635	WP_006740234.1	putative polysaccharide biosynthesis protein	-
HMPREF9318_RS10220	-	470027..471121 (+)	1095	Protein_472	cystathionine gamma-synthase	-
HMPREF9318_RS11295	-	471132..472307 (+)	1176	Protein_473	MalY/PatB family protein	-
HMPREF9318_RS10235 (HMPREF9318_02047)	upp	472377..473006 (+)	630	WP_006739076.1	uracil phosphoribosyltransferase	-
HMPREF9318_RS10240 (HMPREF9318_02048)	clpP	473107..473697 (+)	591	WP_006738636.1	ATP-dependent Clp protease proteolytic subunit	Regulator
HMPREF9318_RS10245 (HMPREF9318_02049)	-	473822..474619 (+)	798	WP_006739760.1	hypothetical protein	-
HMPREF9318_RS10250 (HMPREF9318_02050)	-	474911..475546 (+)	636	WP_006739846.1	hypothetical protein	-
HMPREF9318_RS10255 (HMPREF9318_02051)	-	475661..475909 (+)	249	WP_006739380.1	DUF2129 domain-containing protein	-
HMPREF9318_RS10260 (HMPREF9318_02052)	-	476061..477227 (+)	1167	WP_006738514.1	ABC transporter substrate-binding protein	-
HMPREF9318_RS10265 (HMPREF9318_02053)	-	477294..478163 (+)	870	WP_006740055.1	branched-chain amino acid ABC transporter permease	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21775.98 Da
• Isoelectric Point: 5.0495

>NTDB_id=1113399 HMPREF9318_RS10240 WP_006738636.1 473107..473697(+) (clpP) [Streptococcus urinalis FB127-CNA-2]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGQVEDNMANSIIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQSDMAIAAEHLLKTRNRLEKILADNSKR
TLKQIHKDAERDYWMSAEETLTYGFIDEIMENNELK

Nucleotide

• Length: 591 bp

>NTDB_id=1113399 HMPREF9318_RS10240 WP_006738636.1 473107..473697(+) (clpP) [Streptococcus urinalis FB127-CNA-2]
ATGATTCCTGTAGTTATTGAACAAACTAGTCGTGGCGAACGCTCTTATGATATCTATTCTCGCCTGTTAAAAGATCGCAT
TATCATGTTGACTGGACAAGTAGAAGATAATATGGCAAATTCTATTATTGCTCAACTTCTTTTCTTAGATGCCCAAGATA
GTACAAAAGATATTTACCTCTATGTGAATACACCAGGAGGCTCTGTCTCAGCAGGTTTAGCAATAGTTGATACTATGAAT
TTTATCAAAGCTGATGTCCAAACAATTGTTATGGGTATGGCCGCATCAATGGGTACTATCATTGCATCTAGTGGTACAAA
AGGAAAACGATTCATGCTTCCTAATGCAGAATACATGATTCACCAACCAATGGGTGGTACAGGTGGTGGTACACAACAAA
GTGATATGGCTATTGCCGCTGAACATTTATTGAAAACACGTAACCGTTTAGAAAAAATTCTTGCTGATAATTCAAAACGT
ACCTTAAAACAAATTCATAAAGATGCTGAACGTGATTATTGGATGAGTGCAGAAGAAACCTTAACTTATGGTTTCATTGA
TGAAATTATGGAAAATAATGAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: G5KCI9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pyogenes MGAS315	93.878	100	0.939
clpP	Streptococcus pyogenes JRS4	93.878	100	0.939
clpP	Streptococcus mutans UA159	90.816	100	0.908
clpP	Streptococcus thermophilus LMD-9	89.796	100	0.898
clpP	Streptococcus thermophilus LMG 18311	89.796	100	0.898
clpP	Streptococcus pneumoniae Rx1	89.744	99.49	0.893
clpP	Streptococcus pneumoniae D39	89.744	99.49	0.893
clpP	Streptococcus pneumoniae R6	89.744	99.49	0.893
clpP	Streptococcus pneumoniae TIGR4	89.744	99.49	0.893
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	87.755	100	0.878
clpP	Lactococcus lactis subsp. cremoris KW2	87.245	100	0.872
clpP	Bacillus subtilis subsp. subtilis str. 168	57.143	100	0.571
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	57.513	98.469	0.566