Detailed information NTG0111296

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: G573_RS0100195
• Genome accession: NZ_AUIN01000001
• Coordinates: 37916..38830 (+)
• Length: 304 a.a.
• NCBI ID: WP_027974843.1
• Uniprot ID: -
• Organism: Streptococcus devriesei DSM 19639
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 32916..43830

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G573_RS0100165	-	33264..33956 (+)	693	WP_027974838.1	aspartate/glutamate racemase family protein	-
G573_RS0100170	-	34029..34640 (+)	612	WP_027974839.1	CPBP family intramembrane glutamic endopeptidase	-
G573_RS0100175	-	34673..35071 (+)	399	WP_027974840.1	SRPBCC family protein	-
G573_RS0100180	-	35135..36181 (+)	1047	WP_027974841.1	hypothetical protein	-
G573_RS11480	-	36174..36326 (+)	153	WP_169364428.1	hypothetical protein	-
G573_RS0100190	purB	36492..37790 (+)	1299	WP_027974842.1	adenylosuccinate lyase	-
G573_RS0100195	comR	37916..38830 (+)	915	WP_027974843.1	helix-turn-helix domain-containing protein	Regulator
-	comS	39208..39258 (+)	51	-	-	Regulator
G573_RS0100205	ruvB	39490..40491 (+)	1002	WP_051175676.1	Holliday junction branch migration DNA helicase RuvB	-
G573_RS0100210	-	40520..40942 (+)	423	WP_027974845.1	low molecular weight protein-tyrosine-phosphatase	-
G573_RS0100215	-	41008..41388 (+)	381	WP_027974846.1	membrane protein	-
G573_RS0100220	-	41385..43169 (+)	1785	WP_027974847.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 35942.22 Da
• Isoelectric Point: 4.5735

>NTDB_id=111296 G573_RS0100195 WP_027974843.1 37916..38830(+) (comR) [Streptococcus devriesei DSM 19639]
MLEDFGERVKRLRLEKGLTKEVFCQDESELSMRQLTRIESGESVPTLRKAVYIAERLGVTLDYLTDGRNIDLPSRYKELK
YLLLRTPTYGDQEKLAEREAYFDEIFNHFYDTLPEEEQLVVDALQSKLDIHLSENIDFGVGILNDYFDQILMRKRYQVND
LIIIDLYFSCLTISDLRKDIFDLDKYDKLMQVLLKQSDYLPVEDLFVLNNVLLNNFGILLLLEKYDMIKELIAVANDIMM
KTSDFQKKPIVSILEWKHYLLVENDEARARKSYDSAILFAKLTENTTLREKLEREWQQDSQNRT

Nucleotide

• Length: 915 bp

>NTDB_id=111296 G573_RS0100195 WP_027974843.1 37916..38830(+) (comR) [Streptococcus devriesei DSM 19639]
ATGTTAGAAGATTTTGGGGAGAGAGTAAAGCGGCTGCGGTTAGAAAAGGGACTGACCAAAGAAGTTTTCTGTCAAGATGA
GTCTGAACTGTCCATGCGGCAGCTGACAAGGATTGAGTCGGGGGAGTCTGTTCCTACACTCAGAAAGGCTGTTTATATTG
CTGAGCGTTTGGGTGTGACACTGGATTATCTGACAGATGGGCGAAACATTGACCTGCCTAGCCGCTATAAGGAGCTGAAG
TATCTGTTACTGAGAACACCGACCTACGGCGATCAGGAAAAGCTGGCTGAAAGGGAGGCTTATTTTGATGAGATTTTTAA
TCATTTTTACGACACCCTGCCGGAAGAAGAGCAGCTTGTGGTTGATGCTCTACAGTCGAAATTAGACATTCATCTCAGTG
AAAATATTGATTTTGGGGTTGGCATTTTAAATGATTACTTTGACCAAATCTTGATGCGCAAACGCTATCAGGTAAATGAT
TTAATCATCATTGACCTCTATTTTTCCTGCCTGACCATCAGTGATTTGCGCAAGGATATTTTCGACTTAGATAAATACGA
TAAACTGATGCAGGTTCTGTTAAAGCAGAGTGATTATCTGCCCGTCGAAGATTTATTTGTACTTAATAATGTTCTGCTCA
ATAATTTCGGCATCCTCCTGCTTTTGGAAAAATATGACATGATCAAAGAGCTGATTGCAGTTGCCAATGACATCATGATG
AAAACCTCTGATTTTCAAAAGAAACCTATTGTCAGTATACTCGAGTGGAAGCATTATCTGTTAGTCGAAAATGATGAAGC
ACGGGCTAGAAAAAGCTATGACTCCGCCATTTTATTTGCTAAATTAACTGAGAATACTACATTGAGAGAAAAATTAGAAA
GAGAGTGGCAGCAGGATTCCCAAAACAGGACATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (9-64)

• ComR tetratricopeptide (ComR_TPR) (73-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	74.342	100	0.743
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	50.694	94.737	0.48
comR	Streptococcus pyogenes MGAS315	46.154	98.355	0.454
comR	Streptococcus pyogenes MGAS8232	44.371	99.342	0.441
comR	Streptococcus suis P1/7	43.813	98.355	0.431
comR	Streptococcus suis 05ZYH33	43.813	98.355	0.431
comR	Streptococcus suis D9	40.532	99.013	0.401