Detailed information NTG1111762

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: HMPREF9425_RS07395
• Genome accession: NZ_GL831112
• Coordinates: 1532035..1532625 (-)
• Length: 196 a.a.
• NCBI ID: WP_003093117.1
• Uniprot ID: A0A3E4XDX4
• Organism: Streptococcus vestibularis ATCC 49124
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1527035..1537625

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9425_RS07365 (HMPREF9425_1542)	-	1527246..1528010 (-)	765	WP_003093115.1	ABC transporter ATP-binding protein	-
HMPREF9425_RS07370 (HMPREF9425_1543)	-	1528013..1528963 (-)	951	WP_003097900.1	branched-chain amino acid ABC transporter permease	-
HMPREF9425_RS07375 (HMPREF9425_1544)	-	1528967..1529851 (-)	885	WP_003093154.1	branched-chain amino acid ABC transporter permease	-
HMPREF9425_RS07380 (HMPREF9425_1545)	-	1529895..1531070 (-)	1176	WP_037621571.1	ABC transporter substrate-binding protein	-
HMPREF9425_RS07385 (HMPREF9425_1546)	-	1531225..1531506 (-)	282	WP_003093153.1	DUF2129 domain-containing protein	-
HMPREF9425_RS07390 (HMPREF9425_1547)	-	1531499..1531948 (-)	450	WP_003097905.1	YlbF family regulator	-
HMPREF9425_RS07395 (HMPREF9425_1548)	clpP	1532035..1532625 (-)	591	WP_003093117.1	ATP-dependent Clp protease proteolytic subunit	Regulator
HMPREF9425_RS07400 (HMPREF9425_1549)	upp	1532810..1533439 (-)	630	WP_003097908.1	uracil phosphoribosyltransferase	-
HMPREF9425_RS07405 (HMPREF9425_1551)	-	1533642..1534805 (-)	1164	WP_037621574.1	MalY/PatB family protein	-
HMPREF9425_RS07410 (HMPREF9425_1552)	-	1534816..1535909 (-)	1094	Protein_1509	cystathionine gamma-synthase	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21553.56 Da
• Isoelectric Point: 4.4829

>NTDB_id=1111762 HMPREF9425_RS07395 WP_003093117.1 1532035..1532625(-) (clpP) [Streptococcus vestibularis ATCC 49124]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNNLEQILADNSGQ
SIEKVHVDAERDNWMSAQETLEYGFIDEIMTNNQLK

Nucleotide

• Length: 591 bp

>NTDB_id=1111762 HMPREF9425_RS07395 WP_003093117.1 1532035..1532625(-) (clpP) [Streptococcus vestibularis ATCC 49124]
ATGATTCCTGTAGTTATTGAACAAACATCACGTGGTGAACGTTCTTATGACATTTACTCACGTTTGCTCAAGGATCGTAT
TATCATGTTAACAGGTCCTGTAGAAGATAATATGGCAAACTCAATTATCGCTCAACTCTTGTTCTTAGATGCCCAAGACA
ATACAAAAGATATCTATCTTTATGTTAATACACCTGGTGGGTCAGTTTCAGCAGGTCTTGCCATTGTCGATACAATGAAC
TTCATCAAGTCTGATGTTCAAACCATCGTTATGGGTATGGCAGCATCAATGGGTACAATTATCGCTTCAAGCGGTACTAA
AGGTAAACGTTTCATGTTGCCAAATGCAGAATACATGATTCACCAACCAATGGGTGGTACTGGTGGCGGTACGCAACAAA
CAGATATGGCCATCGCAGCTGAACACTTGCTCAAGACTCGTAATAACTTGGAGCAAATCTTGGCTGATAATTCTGGTCAG
TCAATTGAAAAAGTTCATGTTGATGCTGAACGTGATAATTGGATGAGTGCCCAAGAAACACTTGAATATGGCTTCATTGA
TGAAATCATGACCAACAACCAATTAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A3E4XDX4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus thermophilus LMG 18311	98.98	100	0.99
clpP	Streptococcus thermophilus LMD-9	98.98	100	0.99
clpP	Streptococcus pneumoniae D39	93.846	99.49	0.934
clpP	Streptococcus pneumoniae R6	93.846	99.49	0.934
clpP	Streptococcus pneumoniae TIGR4	93.846	99.49	0.934
clpP	Streptococcus pneumoniae Rx1	93.846	99.49	0.934
clpP	Streptococcus pyogenes MGAS315	90.306	100	0.903
clpP	Streptococcus pyogenes JRS4	90.306	100	0.903
clpP	Streptococcus mutans UA159	88.265	100	0.883
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	88.265	100	0.883
clpP	Lactococcus lactis subsp. cremoris KW2	87.755	100	0.878
clpP	Bacillus subtilis subsp. subtilis str. 168	58.163	100	0.582
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571