Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   HMPREF9425_RS05100 Genome accession   NZ_GL831112
Coordinates   1041479..1042318 (-) Length   279 a.a.
NCBI ID   WP_003093081.1    Uniprot ID   A0AAP2QV18
Organism   Streptococcus vestibularis ATCC 49124     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1036479..1047318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9425_RS05085 (HMPREF9425_1065) - 1037589..1038317 (-) 729 WP_037621492.1 lantibiotic ABC transporter permease -
  HMPREF9425_RS05090 (HMPREF9425_1066) - 1038319..1038996 (-) 678 WP_003097278.1 ABC transporter ATP-binding protein -
  HMPREF9425_RS05095 (HMPREF9425_1067) topA 1039178..1041311 (-) 2134 Protein_1036 type I DNA topoisomerase -
  HMPREF9425_RS05100 (HMPREF9425_1069) dprA 1041479..1042318 (-) 840 WP_003093081.1 DNA-processing protein DprA Machinery gene
  HMPREF9425_RS05105 (HMPREF9425_1070) - 1042385..1043305 (-) 921 WP_003097283.1 ROK family protein -
  HMPREF9425_RS05110 (HMPREF9425_1071) - 1043312..1044082 (-) 771 WP_003097285.1 ribonuclease HII -
  HMPREF9425_RS05115 (HMPREF9425_1072) ylqF 1044069..1044902 (-) 834 WP_003097287.1 ribosome biogenesis GTPase YlqF -
  HMPREF9425_RS05120 (HMPREF9425_1073) - 1045071..1045760 (-) 690 WP_003092569.1 XRE family transcriptional regulator -
  HMPREF9425_RS05125 (HMPREF9425_1074) - 1045855..1046370 (-) 516 WP_037621494.1 transcription repressor NadR -
  HMPREF9425_RS05130 (HMPREF9425_1075) - 1046393..1046920 (-) 528 WP_003093073.1 ECF transporter S component -

Sequence

Protein


Download         Length: 279 a.a.        Molecular weight: 31312.29 Da        Isoelectric Point: 8.6572

>NTDB_id=1111747 HMPREF9425_RS05100 WP_003093081.1 1041479..1042318(-) (dprA) [Streptococcus vestibularis ATCC 49124]
MNNFELFKLKAAGLTNLNILNILDYQKTKDRKLSLRDMAVVSKSKNAVLFMEKYKSLDIKQLKEQFERFPTLSIFDKEYP
IELKHTYNPPVLLYYQGNLDLLIKPKLAVVGARNCSETGKQSVRKIVSELGNQFTIVSGLARGIDTCAHMESLKNKGNTI
AVIGTGLDVYYPKENKALQDYMAKNHLVLTEYGPGEQPLKYHFPERNRIISGLCQGVMVVEAKLRSGSLITCERAMEEGR
DVFAIPGNILDGKSDGCHHLIQEGAKCITTGFDILSEFS

Nucleotide


Download         Length: 840 bp        

>NTDB_id=1111747 HMPREF9425_RS05100 WP_003093081.1 1041479..1042318(-) (dprA) [Streptococcus vestibularis ATCC 49124]
ATGAATAATTTTGAACTTTTTAAACTTAAAGCCGCTGGGTTGACGAATTTGAATATCTTAAATATTTTGGACTATCAAAA
GACTAAAGATAGAAAATTGAGTTTACGTGATATGGCAGTGGTATCCAAGTCTAAAAATGCAGTACTCTTTATGGAAAAGT
ATAAGAGTTTAGATATTAAGCAACTCAAAGAACAGTTTGAACGTTTTCCTACGTTATCGATTTTTGATAAAGAATATCCC
ATTGAGCTGAAGCACACCTATAATCCTCCTGTTCTCCTTTATTATCAGGGAAATCTTGATTTACTGATTAAACCAAAGCT
AGCTGTTGTTGGGGCAAGAAATTGTTCTGAAACAGGCAAGCAGTCTGTTCGAAAAATTGTTAGTGAACTTGGTAATCAGT
TTACTATTGTGAGTGGATTGGCGCGTGGAATTGATACTTGTGCGCATATGGAGTCCTTGAAAAATAAGGGAAACACTATT
GCAGTTATCGGGACAGGACTTGATGTTTATTATCCTAAAGAAAATAAAGCTTTGCAGGACTATATGGCTAAAAACCATTT
AGTTCTTACAGAATATGGACCGGGGGAACAGCCTCTCAAGTACCATTTTCCTGAACGAAATCGGATTATTTCTGGATTGT
GTCAAGGAGTTATGGTCGTAGAAGCTAAGCTTCGCTCGGGAAGCCTGATTACTTGTGAGCGTGCCATGGAAGAAGGTAGA
GATGTTTTTGCTATTCCAGGAAATATTTTAGATGGAAAGTCAGACGGATGCCATCACTTGATTCAGGAGGGTGCAAAGTG
CATCACGACAGGGTTTGACATTCTTTCAGAGTTTTCTTGA

Domains

Predicted by InterproScan.

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-62)

DNA recombination-mediator protein A (DNA_processg_A)

(71-269)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

73.118

100

0.731
  dprA/cilB/dalA Streptococcus mitis SK321

62.95

99.642

0.627
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

62.95

99.642

0.627
  dprA/cilB/dalA Streptococcus pneumoniae D39

62.95

99.642

0.627
  dprA/cilB/dalA Streptococcus pneumoniae R6

62.95

99.642

0.627
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

62.95

99.642

0.627
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

62.59

99.642

0.624
  dprA Lactococcus lactis subsp. cremoris KW2

59.353

99.642

0.591
  dprA Acinetobacter baylyi ADP1

41.473

92.473

0.384
  dprA Latilactobacillus sakei subsp. sakei 23K

40.541

92.832

0.376
  dprA Bacillus subtilis subsp. subtilis str. 168

48.571

75.269

0.366

Multiple sequence alignment