Detailed information    

insolico Bioinformatically predicted

Overview


Name   comD/comD3   Type   Regulator
Locus tag   HMPREF9319_RS11215 Genome accession   NZ_GL397128
Coordinates   1826879..1827193 (-) Length   104 a.a.
NCBI ID   WP_003066552.1    Uniprot ID   E0PG50
Organism   Streptococcus equinus ATCC 700338     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context


Location: 1821879..1832193
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9319_RS08720 (HMPREF9319_1818) rmuC 1822635..1823909 (-) 1275 WP_003066543.1 DNA recombination protein RmuC -
  HMPREF9319_RS08725 (HMPREF9319_1819) - 1823911..1824540 (-) 630 WP_003066545.1 thiamine diphosphokinase -
  HMPREF9319_RS08730 (HMPREF9319_1820) rpe 1824533..1825195 (-) 663 WP_003066548.1 ribulose-phosphate 3-epimerase -
  HMPREF9319_RS08735 (HMPREF9319_1821) rsgA 1825202..1826074 (-) 873 WP_003066549.1 ribosome small subunit-dependent GTPase A -
  HMPREF9319_RS08750 (HMPREF9319_1822) - 1826520..1826747 (-) 228 WP_003066551.1 hypothetical protein -
  HMPREF9319_RS11215 (HMPREF9319_1823) comD/comD3 1826879..1827193 (-) 315 WP_003066552.1 GHKL domain-containing protein Regulator
  HMPREF9319_RS11220 - 1827373..1827582 (-) 210 WP_231729916.1 hypothetical protein -
  HMPREF9319_RS10840 (HMPREF9319_1826) comE/comE2 1827595..1827816 (-) 222 WP_003066558.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  HMPREF9319_RS08760 (HMPREF9319_1827) - 1827788..1828150 (-) 363 WP_003066560.1 bacteriocin immunity protein -
  HMPREF9319_RS08770 (HMPREF9319_1829) - 1828707..1829018 (-) 312 WP_003066564.1 bacteriocin immunity protein -
  HMPREF9319_RS08775 (HMPREF9319_1830) - 1829776..1829913 (+) 138 WP_003066566.1 hypothetical protein -
  HMPREF9319_RS08780 (HMPREF9319_1831) - 1829935..1831242 (-) 1308 WP_003066569.1 sensor histidine kinase -
  HMPREF9319_RS08785 (HMPREF9319_1832) comE/comE1 1831250..1831933 (-) 684 WP_003066571.1 response regulator transcription factor Regulator

Sequence


Protein


Download         Length: 104 a.a.        Molecular weight: 11894.38 Da        Isoelectric Point: 4.6112

>NTDB_id=1111715 HMPREF9319_RS11215 WP_003066552.1 1826879..1827193(-) (comD/comD3) [Streptococcus equinus ATCC 700338]
MDCFEIPRITYIHNLAILFDNRIEAAVLSDVPKISVANFYQDDNFVFMIENSTKEDSIPIDTVYQKGYSSKGDNRSIGLA
TVIEFHQEYGKLPIETSSSNHLFR

Nucleotide


Download         Length: 315 bp        

>NTDB_id=1111715 HMPREF9319_RS11215 WP_003066552.1 1826879..1827193(-) (comD/comD3) [Streptococcus equinus ATCC 700338]
ATGGATTGTTTCGAAATTCCACGTATTACCTACATTCATAACCTTGCTATTCTGTTTGATAATAGGATTGAAGCCGCAGT
ATTATCAGATGTTCCTAAAATATCCGTAGCGAATTTTTATCAAGATGATAACTTTGTTTTTATGATTGAAAATTCAACCA
AAGAAGATAGTATTCCGATTGATACCGTTTATCAAAAAGGCTATTCAAGCAAAGGTGATAATCGTAGTATTGGCTTAGCA
ACAGTTATTGAATTTCATCAAGAATATGGCAAGCTACCCATTGAAACAAGCAGCTCAAATCACCTCTTTAGATAA

Domains


Predicted by InterproScan.

(15-103)


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB E0PG50

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD3 Streptococcus equinus JB1

58.586

95.192

0.558

  comD/comD2 Streptococcus equinus JB1

54.369

99.038

0.538

  comD/comD1 Streptococcus equinus JB1

48.98

94.231

0.462

  comD/blpH Streptococcus mutans UA159

43

96.154

0.413


Multiple sequence alignment