Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   HMPREF9319_RS10840 Genome accession   NZ_GL397128
Coordinates   1827595..1827816 (-) Length   73 a.a.
NCBI ID   WP_003066558.1    Uniprot ID   E0PG53
Organism   Streptococcus equinus ATCC 700338     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1822595..1832816
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9319_RS08720 (HMPREF9319_1818) rmuC 1822635..1823909 (-) 1275 WP_003066543.1 DNA recombination protein RmuC -
  HMPREF9319_RS08725 (HMPREF9319_1819) - 1823911..1824540 (-) 630 WP_003066545.1 thiamine diphosphokinase -
  HMPREF9319_RS08730 (HMPREF9319_1820) rpe 1824533..1825195 (-) 663 WP_003066548.1 ribulose-phosphate 3-epimerase -
  HMPREF9319_RS08735 (HMPREF9319_1821) rsgA 1825202..1826074 (-) 873 WP_003066549.1 ribosome small subunit-dependent GTPase A -
  HMPREF9319_RS08750 (HMPREF9319_1822) - 1826520..1826747 (-) 228 WP_003066551.1 hypothetical protein -
  HMPREF9319_RS11215 (HMPREF9319_1823) comD/comD3 1826879..1827193 (-) 315 WP_003066552.1 GHKL domain-containing protein Regulator
  HMPREF9319_RS11220 - 1827373..1827582 (-) 210 WP_231729916.1 hypothetical protein -
  HMPREF9319_RS10840 (HMPREF9319_1826) comE/comE2 1827595..1827816 (-) 222 WP_003066558.1 LytTR family transcriptional regulator DNA-binding domain-containing protein Regulator
  HMPREF9319_RS08760 (HMPREF9319_1827) - 1827788..1828150 (-) 363 WP_003066560.1 bacteriocin immunity protein -
  HMPREF9319_RS08770 (HMPREF9319_1829) - 1828707..1829018 (-) 312 WP_003066564.1 bacteriocin immunity protein -
  HMPREF9319_RS08775 (HMPREF9319_1830) - 1829776..1829913 (+) 138 WP_003066566.1 hypothetical protein -
  HMPREF9319_RS08780 (HMPREF9319_1831) - 1829935..1831242 (-) 1308 WP_003066569.1 sensor histidine kinase -
  HMPREF9319_RS08785 (HMPREF9319_1832) comE/comE1 1831250..1831933 (-) 684 WP_003066571.1 response regulator transcription factor Regulator
  HMPREF9319_RS08790 (HMPREF9319_1833) - 1831998..1832282 (-) 285 WP_003066573.1 LytTR family DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 73 a.a.        Molecular weight: 8346.75 Da        Isoelectric Point: 9.9655

>NTDB_id=1111714 HMPREF9319_RS10840 WP_003066558.1 1827595..1827816(-) (comE/comE2) [Streptococcus equinus ATCC 700338]
MLVTWTGQRNFYGTIREVKNANHKLFQCQKSYLINPDNGVSLDKKEGIVYCVGGKSCYVSKKSMKELKIKLES

Nucleotide


Download         Length: 222 bp        

>NTDB_id=1111714 HMPREF9319_RS10840 WP_003066558.1 1827595..1827816(-) (comE/comE2) [Streptococcus equinus ATCC 700338]
ATGTTGGTGACATGGACAGGACAGCGTAATTTTTACGGAACAATCAGAGAAGTTAAAAATGCAAATCATAAGCTATTTCA
ATGCCAAAAATCCTATCTGATTAATCCTGATAATGGCGTCAGTTTGGATAAAAAAGAAGGGATTGTTTATTGTGTAGGTG
GAAAATCTTGTTACGTTTCCAAAAAATCCATGAAAGAATTGAAAATTAAACTAGAAAGTTAG

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(2-71)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB E0PG53

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus equinus JB1

61.111

98.63

0.603
  comE/comE1 Streptococcus equinus JB1

38.028

97.26

0.37

Multiple sequence alignment