Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   HMPREF9319_RS09835 Genome accession   NZ_GL397128
Coordinates   2047357..2048622 (+) Length   421 a.a.
NCBI ID   WP_013852370.1    Uniprot ID   A0AAE6YQ67
Organism   Streptococcus equinus ATCC 700338     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2042357..2053622
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9319_RS10585 - 2045975..2046118 (+) 144 WP_160312943.1 hypothetical protein -
  HMPREF9319_RS09830 (HMPREF9319_2054) rlmH 2046667..2047146 (-) 480 WP_003067023.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  HMPREF9319_RS09835 (HMPREF9319_2055) htrA 2047357..2048622 (+) 1266 WP_013852370.1 S1C family serine protease Regulator
  HMPREF9319_RS09840 (HMPREF9319_2056) spo0J 2048682..2049458 (+) 777 WP_003067028.1 ParB/RepB/Spo0J family partition protein Regulator
  HMPREF9319_RS09845 (HMPREF9319_2057) dnaA 2049662..2051017 (+) 1356 WP_003067030.1 chromosomal replication initiator protein DnaA -
  HMPREF9319_RS09850 (HMPREF9319_2058) dnaN 2051175..2052311 (+) 1137 WP_003067033.1 DNA polymerase III subunit beta -
  HMPREF9319_RS09855 (HMPREF9319_2059) - 2052442..2053326 (+) 885 WP_003067036.1 diacylglycerol/lipid kinase family protein -
  HMPREF9319_RS09860 (HMPREF9319_2060) - 2053338..2053532 (+) 195 WP_003067038.1 DUF951 domain-containing protein -

Sequence

Protein


Download         Length: 421 a.a.        Molecular weight: 43814.70 Da        Isoelectric Point: 4.1803

>NTDB_id=1111712 HMPREF9319_RS09835 WP_013852370.1 2047357..2048622(+) (htrA) [Streptococcus equinus ATCC 700338]
MKKIKLPKLPKLPKFNYKNWLKPLGVILVGFIAGIAGTILVLNMAGISITNVSGSSTKTTTSSVSYSNSNDTTKAVEKVQ
DAVVSVINYKSDSSSSASDLYNQMFGNDSDSSSNSSSTDDLTVYSEGSGVIYKKDGDSAYVVTNNHVIDGAEQIEIMLAN
GTKVVGELVGADTYSDIAVVKISSDNVSTVAEFADSDKLTVGETAIAIGSPLGTEYANSVTQGIVSSLSRTVTMTNDDGE
TISTNAIQTDAAINPGNSGGALINIEGQVIGINSSKISSTSSSGESVEGMGFAIPSNDVVSIINQLEENGQVIRPALGIS
MINLSDLSTNAIAQLNIPTSVTSGVVVAAVQSGMPAEGNLEQYDVITAIDDKEVTSTSDLQSILYTHSVGDSVKVTFYRG
TDKKTATIELTKTTQDLSSSN

Nucleotide


Download         Length: 1266 bp        

>NTDB_id=1111712 HMPREF9319_RS09835 WP_013852370.1 2047357..2048622(+) (htrA) [Streptococcus equinus ATCC 700338]
GTGAAAAAAATAAAATTACCAAAATTACCCAAGTTACCAAAATTTAATTACAAAAATTGGTTAAAACCATTGGGTGTCAT
TTTAGTCGGCTTTATAGCTGGTATCGCAGGTACAATACTCGTCCTAAACATGGCAGGTATTTCAATCACTAACGTCAGTG
GTTCAAGTACAAAAACAACAACAAGTAGCGTAAGCTATTCTAACTCTAACGATACAACAAAAGCTGTGGAAAAAGTTCAA
GACGCGGTTGTATCTGTTATTAACTACAAATCAGACTCGTCATCTTCTGCAAGTGACCTCTACAATCAAATGTTTGGCAA
TGACTCAGACAGTAGTAGCAATTCAAGCTCTACAGATGATTTGACTGTTTACAGTGAGGGGTCTGGGGTTATTTACAAAA
AAGATGGTGATTCTGCCTATGTCGTCACTAACAATCACGTTATTGATGGTGCCGAACAAATTGAAATTATGCTTGCTAAT
GGAACAAAAGTTGTTGGTGAGCTAGTCGGAGCAGATACTTATTCAGATATTGCTGTTGTTAAAATTTCTTCTGACAATGT
ATCTACAGTTGCTGAATTTGCCGATTCTGATAAATTGACTGTCGGTGAAACTGCTATCGCTATTGGTAGCCCACTTGGTA
CTGAATATGCTAACTCTGTAACACAAGGTATTGTCTCAAGTCTTAGCCGTACAGTAACCATGACAAATGATGATGGTGAA
ACTATCTCAACAAATGCTATCCAAACAGATGCAGCAATTAACCCAGGTAACTCTGGTGGTGCTTTAATTAACATTGAAGG
ACAAGTTATCGGTATCAATTCAAGTAAGATTTCATCTACATCAAGTTCTGGTGAATCTGTCGAAGGTATGGGATTTGCCA
TTCCATCTAACGATGTTGTATCCATTATTAACCAATTGGAAGAAAATGGGCAAGTTATCCGCCCAGCACTTGGTATTTCA
ATGATAAACTTGAGCGACCTTTCAACTAATGCAATTGCTCAACTTAACATTCCAACAAGTGTAACAAGCGGTGTCGTTGT
TGCCGCTGTTCAATCTGGTATGCCTGCTGAAGGTAATCTCGAACAGTACGATGTCATCACAGCTATTGACGACAAAGAAG
TAACATCTACTTCAGATCTTCAAAGTATTCTTTATACTCATTCTGTTGGTGACTCTGTCAAAGTAACCTTCTACCGTGGA
ACTGATAAGAAAACAGCTACAATTGAATTAACTAAGACAACGCAAGATTTATCTTCCTCAAACTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(315-410)

Trypsin-like peptidase domain (Trypsin_2)

(127-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

64.938

96.2

0.625
  htrA Streptococcus gordonii str. Challis substr. CH1

59.804

96.912

0.58
  htrA Streptococcus pneumoniae D39

57.664

97.625

0.563
  htrA Streptococcus pneumoniae TIGR4

57.664

97.625

0.563
  htrA Streptococcus mitis NCTC 12261

57.664

97.625

0.563
  htrA Streptococcus pneumoniae R6

57.664

97.625

0.563
  htrA Streptococcus pneumoniae Rx1

57.664

97.625

0.563

Multiple sequence alignment