Detailed information NTG1111697

Bioinformatically predicted

Overview

• Name: vicR
• Type: Regulator
• Locus tag: HMPREF9319_RS06885
• Genome accession: NZ_GL397128
• Coordinates: 1448045..1448755 (-)
• Length: 236 a.a.
• NCBI ID: WP_003065770.1
• Uniprot ID: A0AAW6YI35
• Organism: Streptococcus equinus ATCC 700338
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1443045..1453755

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF9319_RS06870 (HMPREF9319_1433)	rnc	1444950..1445636 (-)	687	WP_003065764.1	ribonuclease III	-
HMPREF9319_RS06875 (HMPREF9319_1434)	vicX	1445890..1446699 (-)	810	WP_003065766.1	MBL fold metallo-hydrolase	Regulator
HMPREF9319_RS06880 (HMPREF9319_1435)	vicK	1446700..1448052 (-)	1353	WP_003065768.1	cell wall metabolism sensor histidine kinase VicK	Regulator
HMPREF9319_RS06885 (HMPREF9319_1436)	vicR	1448045..1448755 (-)	711	WP_003065770.1	response regulator YycF	Regulator
HMPREF9319_RS06890 (HMPREF9319_1437)	-	1449060..1449824 (+)	765	WP_003065772.1	amino acid ABC transporter ATP-binding protein	-
HMPREF9319_RS06895 (HMPREF9319_1438)	-	1449835..1450647 (+)	813	WP_013852112.1	transporter substrate-binding domain-containing protein	-
HMPREF9319_RS06900 (HMPREF9319_1439)	-	1450664..1451368 (+)	705	WP_003065775.1	amino acid ABC transporter permease	-
HMPREF9319_RS06905 (HMPREF9319_1440)	-	1451380..1452027 (+)	648	WP_003065777.1	amino acid ABC transporter permease	-
HMPREF9319_RS06910 (HMPREF9319_1441)	-	1452119..1452727 (-)	609	WP_003065779.1	TVP38/TMEM64 family protein	-
HMPREF9319_RS06920 (HMPREF9319_1442)	-	1452975..1453277 (-)	303	WP_003065782.1	PepSY domain-containing protein	-

Sequence

Protein

• Length: 236 a.a.
• Molecular weight: 27119.93 Da
• Isoelectric Point: 4.7040

>NTDB_id=1111697 HMPREF9319_RS06885 WP_003065770.1 1448045..1448755(-) (vicR) [Streptococcus equinus ATCC 700338]
MKKILIVDDEKPISDIIKFNLAKEGYETVTAFDGREAITKFEEENPDLIILDLMLPELDGLEVAKEVRKTSHIPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARVKAHLRRTENIETAVAEENASASNSEITIGDLKILPDAFVAQKRGEDIE
LTHREFELLHHLATHMGQVMTREYLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide

• Length: 711 bp

>NTDB_id=1111697 HMPREF9319_RS06885 WP_003065770.1 1448045..1448755(-) (vicR) [Streptococcus equinus ATCC 700338]
ATGAAAAAAATTCTTATCGTGGATGATGAAAAACCAATTTCGGATATTATTAAATTTAATTTAGCTAAAGAAGGTTATGA
AACTGTAACGGCTTTTGATGGTCGTGAAGCTATTACAAAGTTTGAGGAAGAAAATCCAGATTTAATTATCCTGGATTTGA
TGTTGCCAGAGTTGGATGGGCTTGAAGTGGCTAAGGAAGTTCGCAAGACAAGTCATATTCCAATCATCATGTTGTCTGCT
AAGGATAGCGAGTTTGATAAAGTTATCGGTCTTGAAATTGGTGCAGATGACTATGTAACCAAACCATTTTCAAATCGTGA
ATTGTTGGCGCGTGTTAAAGCGCACCTTCGTCGTACAGAAAATATTGAAACAGCAGTTGCTGAAGAAAATGCTTCGGCTT
CAAATTCAGAAATCACAATTGGCGACTTAAAAATTTTACCAGATGCCTTTGTAGCACAAAAACGTGGTGAAGATATCGAA
TTAACACACCGTGAGTTTGAATTGCTTCATCATTTGGCAACTCATATGGGACAAGTCATGACTCGTGAATATCTTTTGGA
AACCGTTTGGGGCTATGATTATTTTGGTGATGTGCGTACGGTTGATGTAACGATTCGTCGTTTACGCGAAAAAATTGAAG
ATACACCAAGCCGTCCAGAATATATTTTGACACGTCGGGGTGTTGGGTACTACATGAAGTCATATGAATGA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (156-231)

• Response regulator receiver domain (Response_reg) (4-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicR	Streptococcus mutans UA159	90.678	100	0.907
micA	Streptococcus pneumoniae Cp1015	77.35	99.153	0.767
covR	Streptococcus salivarius strain HSISS4	47.414	98.305	0.466
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.69	98.305	0.449
scnR	Streptococcus mutans UA159	37.288	100	0.373