Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   HMPREF9319_RS06880 Genome accession   NZ_GL397128
Coordinates   1446700..1448052 (-) Length   450 a.a.
NCBI ID   WP_003065768.1    Uniprot ID   A0AAE6YTG0
Organism   Streptococcus equinus ATCC 700338     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1441700..1453052
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMPREF9319_RS06870 (HMPREF9319_1433) rnc 1444950..1445636 (-) 687 WP_003065764.1 ribonuclease III -
  HMPREF9319_RS06875 (HMPREF9319_1434) vicX 1445890..1446699 (-) 810 WP_003065766.1 MBL fold metallo-hydrolase Regulator
  HMPREF9319_RS06880 (HMPREF9319_1435) vicK 1446700..1448052 (-) 1353 WP_003065768.1 cell wall metabolism sensor histidine kinase VicK Regulator
  HMPREF9319_RS06885 (HMPREF9319_1436) vicR 1448045..1448755 (-) 711 WP_003065770.1 response regulator YycF Regulator
  HMPREF9319_RS06890 (HMPREF9319_1437) - 1449060..1449824 (+) 765 WP_003065772.1 amino acid ABC transporter ATP-binding protein -
  HMPREF9319_RS06895 (HMPREF9319_1438) - 1449835..1450647 (+) 813 WP_013852112.1 transporter substrate-binding domain-containing protein -
  HMPREF9319_RS06900 (HMPREF9319_1439) - 1450664..1451368 (+) 705 WP_003065775.1 amino acid ABC transporter permease -
  HMPREF9319_RS06905 (HMPREF9319_1440) - 1451380..1452027 (+) 648 WP_003065777.1 amino acid ABC transporter permease -
  HMPREF9319_RS06910 (HMPREF9319_1441) - 1452119..1452727 (-) 609 WP_003065779.1 TVP38/TMEM64 family protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51398.46 Da        Isoelectric Point: 4.7297

>NTDB_id=1111696 HMPREF9319_RS06880 WP_003065768.1 1446700..1448052(-) (vicK) [Streptococcus equinus ATCC 700338]
MNDTMLQNLTYFEQAILFLLAFVAVYFVYLAIRDYRTSVNIRRLSGKVRELITGKYTEDIIIEKDRDLAELADQLNDLST
VFRLAQENLAQEKNRLASILSYMTDGVLATDRAGNITMINQTALQQLNLEHEEALQMNIVDILGADSTYSYHDLVSKTPE
IVLNRRDGTGEFITLRIRFALNRRDSGFISGLIAVLHDTTEQEKEDRERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMIRMISDLLNLSRIDNQTVQLEVEMTNFTAFMTSILNRFDQIKSQHTISGKQYEIVRDYPIKS
IWLEIDPDKMTQVLDNILNNAIKYSPDGGKITVSMKTTETQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGSG
LGLAIAKEIVKQHKGFIWAQSTYGKGSTFTIVLPYEKDSEIYDEWEDEEE

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=1111696 HMPREF9319_RS06880 WP_003065768.1 1446700..1448052(-) (vicK) [Streptococcus equinus ATCC 700338]
ATGAATGATACAATGTTACAAAATTTAACTTATTTTGAACAAGCCATTCTCTTTCTTTTAGCATTTGTCGCAGTTTATTT
TGTTTATTTAGCGATAAGAGATTATCGAACTTCTGTTAATATTCGACGTTTGAGTGGTAAAGTGCGAGAGCTTATCACAG
GAAAATATACAGAAGATATTATTATTGAAAAAGATAGAGACTTAGCTGAGTTAGCTGACCAATTAAATGATTTGTCAACA
GTCTTTCGTTTAGCACAGGAAAATTTGGCGCAAGAAAAGAATCGTTTAGCAAGTATCTTATCCTATATGACAGACGGTGT
CTTGGCGACTGACCGTGCTGGAAATATCACAATGATTAATCAAACCGCGCTACAACAACTCAATTTAGAGCACGAAGAAG
CTTTGCAGATGAATATTGTTGATATTTTAGGAGCTGATAGTACTTATAGTTATCATGATTTGGTGTCAAAAACACCTGAA
ATTGTCTTGAACCGTCGTGACGGAACAGGTGAATTTATTACTTTACGTATTCGATTTGCTCTAAATCGTCGTGATAGTGG
CTTTATTTCAGGGTTGATTGCTGTTTTGCATGACACAACCGAACAAGAAAAAGAAGACCGTGAGCGTCGCCTTTTCGTTT
CTAATGTTAGTCATGAATTGCGAACACCATTAACATCTGTAAAATCTTATCTGGAAGCTTTAGATGAAGGGGCACTCAAA
GAAGACATTGCGCCAAGCTTTATCAAAGTGTCTTTAGATGAAACAAACCGTATGATTCGTATGATTTCAGACTTACTTAA
TTTATCGCGTATTGATAATCAGACGGTTCAACTGGAAGTGGAAATGACCAATTTCACAGCTTTTATGACATCAATTCTTA
ACCGTTTTGATCAAATTAAAAGCCAACATACAATCAGTGGAAAACAGTATGAGATTGTCAGGGATTATCCGATTAAATCA
ATCTGGCTTGAAATTGATCCTGATAAGATGACGCAGGTTTTGGATAATATCCTTAATAATGCTATCAAATATTCACCAGA
TGGTGGAAAAATCACAGTTAGCATGAAAACGACGGAAACACAGTTGATTATCTCAATCTCTGATGAAGGGCTTGGTATTC
CTAAGAAAGATTTGCCATTGATTTTCGACCGTTTCTATCGTGTGGATAAGGCTCGAAGTCGTGCCCAAGGTGGTTCAGGA
CTCGGCTTAGCTATCGCAAAAGAAATTGTCAAACAACATAAAGGTTTTATTTGGGCACAAAGTACTTACGGAAAAGGGTC
GACCTTTACAATTGTACTTCCTTACGAAAAAGATTCTGAAATTTATGATGAATGGGAGGATGAAGAAGAGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-189)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.94

92.222

0.691
  micB Streptococcus pneumoniae Cp1015

66.038

94.222

0.622

Multiple sequence alignment