Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ACN076_RS07675 Genome accession   NZ_CP184836
Coordinates   1563451..1564101 (-) Length   216 a.a.
NCBI ID   WP_420789769.1    Uniprot ID   -
Organism   Streptococcus sp. K0074     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1558451..1569101
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACN076_RS07660 (ACN076_07660) - 1559052..1560236 (-) 1185 WP_420789766.1 hypothetical protein -
  ACN076_RS07665 (ACN076_07665) - 1560240..1560827 (-) 588 WP_420789767.1 ATP-binding cassette domain-containing protein -
  ACN076_RS07670 (ACN076_07670) comEC/celB 1561227..1563467 (-) 2241 WP_420789768.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ACN076_RS07675 (ACN076_07675) comEA/celA/cilE 1563451..1564101 (-) 651 WP_420789769.1 helix-hairpin-helix domain-containing protein Machinery gene
  ACN076_RS07680 (ACN076_07680) - 1564169..1564738 (-) 570 WP_420789770.1 GNAT family N-acetyltransferase -
  ACN076_RS07685 (ACN076_07685) ald 1564909..1566021 (+) 1113 WP_420789771.1 alanine dehydrogenase -
  ACN076_RS07690 (ACN076_07690) - 1566078..1567073 (-) 996 WP_420789772.1 PhoH family protein -
  ACN076_RS07695 (ACN076_07695) - 1567158..1567373 (-) 216 WP_001232089.1 YozE family protein -
  ACN076_RS07700 (ACN076_07700) cvfB 1567382..1568236 (-) 855 WP_020900277.1 RNA-binding virulence regulatory protein CvfB -
  ACN076_RS07705 (ACN076_07705) frr 1568296..1568853 (-) 558 WP_001262225.1 ribosome recycling factor -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23248.61 Da        Isoelectric Point: 6.5075

>NTDB_id=1111466 ACN076_RS07675 WP_420789769.1 1563451..1564101(-) (comEA/celA/cilE) [Streptococcus sp. K0074]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPASHIPVKETNLQAEVVAVSKDSVSEKEVKKEDKEEPVEQDLITVDVKG
AVKAPGIYDLPVGSRVNDAVQKAGGLTDQADSKSLNLAQKVSDEALVYVPTKGEEVASQQTTSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHRETNGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=1111466 ACN076_RS07675 WP_420789769.1 1563451..1564101(-) (comEA/celA/cilE) [Streptococcus sp. K0074]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATTGTCATCTGTACTGGTCTGGGCTTACTTGTAGGAGGATT
TTTCCTGCTAAAGCCAGCTTCACACATACCTGTCAAAGAAACGAATTTGCAGGCTGAAGTTGTAGCTGTTTCCAAGGATT
CGGTATCCGAAAAGGAAGTAAAGAAGGAAGATAAGGAAGAACCGGTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTTAAAGCACCTGGAATTTATGATTTGCCGGTGGGTAGTCGGGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGATCAAGCAGACAGCAAATCGCTTAATCTAGCTCAGAAAGTTAGTGATGAAGCTCTGGTTTATGTTCCCACTAAGGGGG
AAGAAGTGGCTAGTCAACAGACTACTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAGCTTAAACAGGTCAAAGGATTAGGTGGCAAACGAGCTCAGGACATTATCGATCATCGTGAGACGAATGG
CAAATTCAAGTCGGTTGATGAACTTAAGAAGGTCTCTGGCATTGGTGCTAAAACGATAGAAAAGCTAAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

94.444

100

0.944
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

93.056

100

0.931
  comEA/celA/cilE Streptococcus pneumoniae D39

92.13

100

0.921
  comEA/celA/cilE Streptococcus pneumoniae R6

92.13

100

0.921
  comEA/celA/cilE Streptococcus pneumoniae Rx1

92.13

100

0.921
  comEA/celA/cilE Streptococcus mitis SK321

91.204

100

0.912
  comEA Lactococcus lactis subsp. cremoris KW2

42.731

100

0.449
  comEA Latilactobacillus sakei subsp. sakei 23K

34.335

100

0.37

Multiple sequence alignment