Detailed information NTG1111465

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ACN076_RS07670
• Genome accession: NZ_CP184836
• Coordinates: 1561227..1563467 (-)
• Length: 746 a.a.
• NCBI ID: WP_420789768.1
• Uniprot ID: -
• Organism: Streptococcus sp. K0074
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1556227..1568467

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACN076_RS07640 (ACN076_07640)	-	1557131..1557511 (-)	381	WP_070842964.1	VOC family protein	-
ACN076_RS07645 (ACN076_07645)	rplT	1557570..1557929 (-)	360	WP_000124834.1	50S ribosomal protein L20	-
ACN076_RS07650 (ACN076_07650)	rpmI	1557981..1558181 (-)	201	WP_001125943.1	50S ribosomal protein L35	-
ACN076_RS07655 (ACN076_07655)	infC	1558214..1558744 (-)	531	WP_000848180.1	translation initiation factor IF-3	-
ACN076_RS07660 (ACN076_07660)	-	1559052..1560236 (-)	1185	WP_420789766.1	hypothetical protein	-
ACN076_RS07665 (ACN076_07665)	-	1560240..1560827 (-)	588	WP_420789767.1	ATP-binding cassette domain-containing protein	-
ACN076_RS07670 (ACN076_07670)	comEC/celB	1561227..1563467 (-)	2241	WP_420789768.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ACN076_RS07675 (ACN076_07675)	comEA/celA/cilE	1563451..1564101 (-)	651	WP_420789769.1	helix-hairpin-helix domain-containing protein	Machinery gene
ACN076_RS07680 (ACN076_07680)	-	1564169..1564738 (-)	570	WP_420789770.1	GNAT family N-acetyltransferase	-
ACN076_RS07685 (ACN076_07685)	ald	1564909..1566021 (+)	1113	WP_420789771.1	alanine dehydrogenase	-
ACN076_RS07690 (ACN076_07690)	-	1566078..1567073 (-)	996	WP_420789772.1	PhoH family protein	-
ACN076_RS07695 (ACN076_07695)	-	1567158..1567373 (-)	216	WP_001232089.1	YozE family protein	-
ACN076_RS07700 (ACN076_07700)	cvfB	1567382..1568236 (-)	855	WP_020900277.1	RNA-binding virulence regulatory protein CvfB	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84651.84 Da
• Isoelectric Point: 9.0542

>NTDB_id=1111465 ACN076_RS07670 WP_420789768.1 1561227..1563467(-) (comEC/celB) [Streptococcus sp. K0074]
MLQWIKNLPIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLICLFFQFAWKSASKVLIICGIFGFWFLFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKADGRIFQVYYKFQSEEEKETFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQAY
LKTQGIYQTLNIKKIQSLQKVSSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMDGFKKLFLRSGLTQEKLKWLTYPFSLLYAGMTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFII
MPNFFLTAGGVLSCAYAFILTMTSKEEEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFAFSFLYPVIQLNFIFEWLEGTIRLVSQLASRPLVFGQPNAWLLILLLISLALIYDLRKNVKKLAVLSLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESDKKIEKWQEKVTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLKQKEFVAELQATQTKVRSVSVGENLPIFGSQLEVLSPRKIGDGDHEDSLVLYGKL
LDKNFLFTGNLEEKGEKDLLKQYPDLEVDVLKASQHGSKKSSSSAFLEQLKPEITLISVGKNNRTKLPHQETLTRLETIN
SKVYRTDQQGAIRFKGWNSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=1111465 ACN076_RS07670 WP_420789768.1 1561227..1563467(-) (comEC/celB) [Streptococcus sp. K0074]
ATGTTACAGTGGATTAAGAACCTCCCTATTCCCCTAATTTACCTGAGTTTTCTATTGCTCTGGCTTTACTACGCTATTTT
CTCAGCATCCTATCTTGCTTTGTTGGGTTTCGTTTTTCTGCTAATCTGTCTTTTTTTCCAATTTGCTTGGAAATCTGCTA
GTAAAGTTCTAATAATTTGCGGAATCTTTGGCTTCTGGTTTCTGTTTCAAAATTGGCAACAGAGTCAAGCTAGTCAAAAC
CTAGCGGATTCTGTTGAAAGGGTACGGATTTTGCCCGACACTATTAAGGTCAATGGTGACAGTCTATCCTTTCGTGGCAA
GGCTGATGGACGCATTTTTCAAGTCTATTATAAATTCCAGTCCGAGGAGGAGAAAGAAACCTTTCAAGCTTTAACCGACC
TTCATGAGATAGGACTAGAAGGAAAACTTTCAGAACCAGAGGGGCAGAGAAATTTTGGTGGCTTTGACTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAAAAATCCAGTCACTTCAAAAGGTTAGCAGTTGGGATATAGG
TGAAAACCTGTCCAGCTTACGTCGAAAGGCTGTAGTTTGGATTAAGACACATTTTCCAGACCCTATGCGCAATTACATGA
CAGGGCTTTTGCTAGGGCATCTGGACACTGACTTTGAGGAGATGAATGAACTTTATTCTAGTCTAGGAATTATCCACCTC
TTTGCCTTGTCGGGCATGCAGGTAGGTTTTTTCATGGATGGATTTAAGAAACTATTCTTGCGATCAGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACCTATCCCTTTTCCCTTCTCTATGCTGGTATGACAGGATTTTCAGCTTCGGTCATTCGCAGTC
TCTTGCAAAAATTACTGGCTCAACATGGTGTTAAGGGCTTGGATAATTTTGCCTTGACGGTTCTTGTCCTCTTTATTATC
ATGCCTAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCTTGACCATGACCAGCAAAGAAGA
GGAGGGGCTCAAGGCTGTTGCTAGAGAAAGTCTAGTCATATCCTTGGGCATATTGCCCATTCTGTCCTTCTATTTTGCAG
AATTTCAGCCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTAGTCTTCTTACCGCTCCTGTCTATT
TTATTTGCCTTTTCATTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAGTGGTTGGAGGGGACTATTCGCTTGGT
ATCGCAGCTGGCAAGCAGACCGCTTGTCTTTGGACAACCTAATGCATGGCTTTTAATTTTATTGTTAATTTCCTTGGCTT
TGATCTATGATTTGAGGAAAAATGTTAAAAAGCTAGCAGTGTTGAGCTTATTGATTACAGGTCTCTTTTTATTGACCAAG
CATCCACTGGAAAATGAAATTACCATGCTGGACGTGGGACAAGGCGAAAGTATTTTCCTAAGGGATGTAACCGGTAAAAC
CATTCTCATAGATGTCGGTGGCAAGGCAGAATCTGATAAGAAAATTGAAAAATGGCAAGAAAAGGTAACGACTAGCAATG
CCCAGCGAACCTTGATTCCCTACCTCAAAAGTCGTGGAGTGGCCAAGATTGACCAGCTAATTTTGACCAATACGGACAAG
GAACATGTTGGAGATTTGTTGGAGGTGACCAAGGCTTTCCATGTAGGGGAAATTTTAGTGTCAAAAGGCAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACCAAGGTGCGTAGTGTGTCAGTGGGAGAGAACTTGCCAATTTTTG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGAAAATAGGAGATGGAGATCATGAAGATTCCCTGGTTTTGTATGGAAAACTC
TTGGATAAAAATTTTCTTTTCACAGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCAATATCCTGACTTAGA
GGTGGATGTTTTGAAAGCTAGCCAACATGGCTCTAAAAAATCATCAAGTTCAGCTTTTCTAGAACAGCTCAAACCAGAGA
TCACTCTCATCTCAGTTGGAAAGAACAATCGAACGAAACTCCCCCATCAGGAAACCCTGACCCGACTGGAAACGATCAAT
AGCAAAGTTTACCGAACTGACCAGCAAGGGGCTATACGCTTTAAGGGGTGGAATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-700)

• Competence protein (Competence) (216-459)

• Domain of unknown function (DUF4131) (DUF4131) (30-177)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	93.566	100	0.936
comEC/celB	Streptococcus mitis NCTC 12261	92.483	99.866	0.924
comEC/celB	Streptococcus pneumoniae Rx1	91.823	100	0.918
comEC/celB	Streptococcus pneumoniae D39	91.823	100	0.918
comEC/celB	Streptococcus pneumoniae R6	91.823	100	0.918
comEC/celB	Streptococcus pneumoniae TIGR4	91.555	100	0.916
comEC	Lactococcus lactis subsp. cremoris KW2	45.209	99.33	0.449