Detailed information NTG1111450

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: ACN076_RS04485
• Genome accession: NZ_CP184836
• Coordinates: 928280..928870 (+)
• Length: 196 a.a.
• NCBI ID: WP_000613475.1
• Uniprot ID: F9HD24
• Organism: Streptococcus sp. K0074
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 923280..933870

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACN076_RS04455 (ACN076_04455)	-	923575..924096 (-)	522	WP_261024379.1	DUF1697 domain-containing protein	-
ACN076_RS04460 (ACN076_04460)	-	924145..925317 (-)	1173	WP_261024378.1	NAD(P)/FAD-dependent oxidoreductase	-
ACN076_RS04465 (ACN076_04465)	-	925376..926221 (-)	846	WP_261024377.1	DegV family protein	-
ACN076_RS04470 (ACN076_04470)	-	926346..926903 (+)	558	WP_261024375.1	TetR/AcrR family transcriptional regulator	-
ACN076_RS04475 (ACN076_04475)	-	926922..927389 (+)	468	WP_000136973.1	deoxycytidylate deaminase	-
ACN076_RS04480 (ACN076_04480)	upp	927478..928107 (+)	630	WP_000515974.1	uracil phosphoribosyltransferase	-
ACN076_RS04485 (ACN076_04485)	clpP	928280..928870 (+)	591	WP_000613475.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
ACN076_RS04490 (ACN076_04490)	-	928949..929236 (+)	288	WP_000462125.1	YlbG family protein	-
ACN076_RS04495 (ACN076_04495)	-	929304..930464 (+)	1161	WP_000726119.1	ABC transporter substrate-binding protein	-
ACN076_RS04500 (ACN076_04500)	-	930578..931447 (+)	870	WP_000941421.1	branched-chain amino acid ABC transporter permease	-
ACN076_RS04505 (ACN076_04505)	-	931451..932407 (+)	957	WP_261043423.1	branched-chain amino acid ABC transporter permease	-
ACN076_RS04510 (ACN076_04510)	-	932407..933171 (+)	765	WP_001185997.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21340.32 Da
• Isoelectric Point: 4.4910

>NTDB_id=1111450 ACN076_RS04485 WP_000613475.1 928280..928870(+) (clpP) [Streptococcus sp. K0074]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide

• Length: 591 bp

>NTDB_id=1111450 ACN076_RS04485 WP_000613475.1 928280..928870(+) (clpP) [Streptococcus sp. K0074]
ATGATTCCTGTCGTTATTGAACAAACAAGCCGTGGAGAACGTTCCTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACTGGTCCAGTTGAAGACAACATGGCCAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCTGGTGGTTCCGTTTCAGCTGGTTTGGCAATCGTTGATACCATGAAC
TTTATTAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGGACGGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATCCACCAACCGATGGGTGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCGATCGCTGCAGAACACTTACTTAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATCGAAAAAGTCCATGCAGATGCAGAACGCGATAACTGGATGAGTGCTCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: F9HD24

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	99.49	100	0.995
clpP	Streptococcus pneumoniae D39	99.49	100	0.995
clpP	Streptococcus pneumoniae R6	99.49	100	0.995
clpP	Streptococcus pneumoniae TIGR4	99.49	100	0.995
clpP	Streptococcus thermophilus LMG 18311	93.333	99.49	0.929
clpP	Streptococcus thermophilus LMD-9	93.333	99.49	0.929
clpP	Streptococcus pyogenes JRS4	91.282	99.49	0.908
clpP	Streptococcus pyogenes MGAS315	91.282	99.49	0.908
clpP	Streptococcus mutans UA159	86.224	100	0.862
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	85.128	99.49	0.847
clpP	Lactococcus lactis subsp. cremoris KW2	84.615	99.49	0.842
clpP	Bacillus subtilis subsp. subtilis str. 168	58.854	97.959	0.577
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571