Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   ACNR93_RS04760 Genome accession   NZ_CP184736
Coordinates   951782..952456 (-) Length   224 a.a.
NCBI ID   WP_074450515.1    Uniprot ID   A0A1G9I8L9
Organism   Streptococcus equinus strain NM-2-29     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 946782..957456
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNR93_RS04735 (ACNR93_04735) deoC 947265..947930 (-) 666 WP_021142326.1 deoxyribose-phosphate aldolase -
  ACNR93_RS04740 (ACNR93_04740) - 948433..949023 (-) 591 WP_420543190.1 class I SAM-dependent methyltransferase -
  ACNR93_RS04745 (ACNR93_04745) coaA 949137..950057 (+) 921 WP_420543191.1 type I pantothenate kinase -
  ACNR93_RS04750 (ACNR93_04750) rpsT 950133..950384 (+) 252 WP_004231769.1 30S ribosomal protein S20 -
  ACNR93_RS04755 (ACNR93_04755) ciaH 950467..951792 (-) 1326 WP_420543192.1 sensor histidine kinase Regulator
  ACNR93_RS04760 (ACNR93_04760) ciaR 951782..952456 (-) 675 WP_074450515.1 response regulator transcription factor Regulator
  ACNR93_RS04765 (ACNR93_04765) - 952609..955152 (-) 2544 WP_420543193.1 M1 family metallopeptidase -
  ACNR93_RS04770 (ACNR93_04770) phoU 955360..956013 (-) 654 WP_024344053.1 phosphate signaling complex protein PhoU -
  ACNR93_RS04775 (ACNR93_04775) pstB 956045..956803 (-) 759 WP_045797897.1 phosphate ABC transporter ATP-binding protein PstB -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25373.98 Da        Isoelectric Point: 4.3369

>NTDB_id=1110949 ACNR93_RS04760 WP_074450515.1 951782..952456(-) (ciaR) [Streptococcus equinus strain NM-2-29]
MIKILLVEDDLSLSNSIFDFLDDFADVMQVFDGAEGLYEAESGVYDLILLDLMLPEKDGFQVLKELREKGISTPVLIMTA
KESLDDKGHGFELGADDYLTKPFYLEELKMRIQALLKRSGKFNNNTLSYHELTADTSTNTTTVNGEKVELLGKEFDLLVY
FLQNQNVILPKSQIFDRIWGFDSDTTISVVEVYVSKIRKKLKGTSFADNLQTLRSVGYILKDAE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=1110949 ACNR93_RS04760 WP_074450515.1 951782..952456(-) (ciaR) [Streptococcus equinus strain NM-2-29]
ATGATTAAAATTTTATTAGTAGAAGACGATTTGAGCTTATCAAATTCAATTTTTGATTTTTTGGATGATTTTGCGGATGT
CATGCAGGTTTTTGATGGCGCAGAAGGCTTATATGAAGCAGAAAGTGGTGTTTATGACCTTATTTTGCTTGATTTGATGT
TGCCAGAAAAAGATGGTTTCCAAGTTCTTAAAGAATTACGTGAAAAAGGCATTTCAACACCTGTTTTGATTATGACAGCT
AAAGAAAGTCTTGATGACAAAGGACATGGATTTGAATTAGGTGCTGATGATTACCTAACAAAACCATTTTATCTTGAAGA
ACTTAAGATGCGTATTCAAGCTCTTTTAAAACGTTCAGGTAAATTTAATAACAATACTTTGTCATATCATGAATTAACTG
CGGATACTTCAACAAATACAACAACTGTTAATGGTGAAAAAGTTGAATTACTAGGTAAAGAGTTTGATTTGTTAGTATAC
TTTTTGCAAAACCAAAATGTCATTTTGCCAAAATCACAAATTTTTGACCGTATTTGGGGCTTTGACAGTGATACAACAAT
TTCAGTTGTTGAAGTATATGTTTCAAAAATTCGTAAAAAACTCAAAGGCACTAGTTTTGCCGATAATCTTCAAACACTAC
GTAGTGTAGGTTACATATTGAAAGATGCTGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1G9I8L9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

91.928

99.554

0.915
  ciaR Streptococcus pneumoniae Rx1

87.5

100

0.875
  ciaR Streptococcus pneumoniae D39

87.5

100

0.875
  ciaR Streptococcus pneumoniae R6

87.5

100

0.875
  ciaR Streptococcus pneumoniae TIGR4

87.5

100

0.875
  covR Lactococcus lactis subsp. lactis strain DGCC12653

38.767

100

0.393
  micA Streptococcus pneumoniae Cp1015

34.764

100

0.362
  vicR Streptococcus mutans UA159

34.764

100

0.362

Multiple sequence alignment