Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   ACNVED_RS08805 Genome accession   NZ_CP183303
Coordinates   2015234..2016454 (+) Length   406 a.a.
NCBI ID   WP_419418653.1    Uniprot ID   -
Organism   Legionella sp. D16C41     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2010234..2021454
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACNVED_RS08785 (ACNVED_08785) - 2010762..2011085 (-) 324 WP_419418650.1 DUF1820 family protein -
  ACNVED_RS08790 (ACNVED_08790) - 2011447..2012172 (+) 726 WP_419418651.1 hypothetical protein -
  ACNVED_RS08795 (ACNVED_08795) - 2012443..2013186 (-) 744 WP_419418652.1 methyltransferase domain-containing protein -
  ACNVED_RS08800 (ACNVED_08800) pilB 2013507..2015229 (+) 1723 Protein_1731 type IV-A pilus assembly ATPase PilB -
  ACNVED_RS08805 (ACNVED_08805) pilC 2015234..2016454 (+) 1221 WP_419418653.1 type II secretion system F family protein Machinery gene
  ACNVED_RS08810 (ACNVED_08810) - 2016622..2017485 (+) 864 WP_419418654.1 prepilin peptidase -
  ACNVED_RS08815 (ACNVED_08815) - 2017496..2018086 (-) 591 WP_419418655.1 hypothetical protein -
  ACNVED_RS08820 (ACNVED_08820) - 2018099..2018551 (-) 453 WP_419418656.1 hypothetical protein -
  ACNVED_RS08825 (ACNVED_08825) - 2018807..2019439 (-) 633 WP_419418657.1 NUDIX hydrolase -
  ACNVED_RS08830 (ACNVED_08830) - 2019721..2020530 (+) 810 WP_419418658.1 pyruvate, water dikinase regulatory protein -

Sequence

Protein


Download         Length: 406 a.a.        Molecular weight: 44867.94 Da        Isoelectric Point: 10.2886

>NTDB_id=1105176 ACNVED_RS08805 WP_419418653.1 2015234..2016454(+) (pilC) [Legionella sp. D16C41]
MERNKNTVITYRWEGINRSGEKVNGIIESNSIAIAKATLRKQGIITNKVVKKRKSLFDKKNRKITAGDITAFTRQLATML
NAGIPLIQTFDIIAKGQTNQKVKTLVETIKKDVESGLTLTEALKKHPKYFNELYYNLVDAGEKSGSLDVMLAKIATYKEK
IEKIKRKIKKALTYPIAVLVIAFLVTAGLLIFVIPQFEALFKGFGADLPALTRGVISLSQLFQTYWYIIFGAIGIGIYAF
IRARNRSVNFAHNVDRFMLKIPIIGSILQKAAIARFARTLSITFAAGLPLVEALYAVAGATGNIIYAQATNKIREEVSNG
QQIRIAMDNTHLFPSMVIQMIAIGEESGALEQMLTKVADFYEEEVDNAVDSLSNLLEPIIMSILGILVGGLVIAMYLPIF
KLGSVV

Nucleotide


Download         Length: 1221 bp        

>NTDB_id=1105176 ACNVED_RS08805 WP_419418653.1 2015234..2016454(+) (pilC) [Legionella sp. D16C41]
ATGGAAAGAAACAAAAATACAGTCATTACTTATCGTTGGGAAGGCATTAACCGTTCTGGTGAAAAAGTAAATGGTATTAT
AGAATCAAATAGCATTGCCATTGCCAAAGCTACTTTGCGAAAACAAGGGATTATTACTAATAAAGTTGTAAAAAAACGCA
AATCTCTCTTTGATAAGAAAAATAGAAAAATAACTGCTGGTGACATTACCGCTTTCACGCGTCAATTAGCGACTATGCTT
AATGCTGGTATTCCGCTTATACAAACTTTTGATATTATTGCTAAAGGTCAAACTAATCAAAAAGTAAAAACACTTGTTGA
AACAATTAAAAAAGACGTTGAATCAGGATTAACATTAACAGAAGCTTTAAAAAAACATCCAAAATATTTTAATGAACTTT
ATTATAATTTAGTTGATGCTGGTGAAAAATCAGGTTCATTGGATGTCATGCTCGCTAAAATTGCCACCTACAAAGAAAAA
ATAGAAAAAATTAAACGAAAAATTAAAAAAGCGCTAACTTATCCTATAGCAGTGTTAGTTATTGCATTTTTAGTTACAGC
AGGTTTATTAATTTTCGTAATTCCGCAATTTGAAGCGCTTTTTAAAGGCTTTGGTGCCGATCTTCCCGCACTAACGCGCG
GAGTTATAAGTTTATCGCAACTTTTTCAAACCTATTGGTATATTATTTTTGGTGCTATTGGTATTGGAATTTATGCTTTT
ATACGAGCTCGAAATCGATCAGTCAATTTTGCTCATAACGTGGATCGTTTTATGCTTAAAATTCCAATTATCGGCTCTAT
TTTGCAGAAAGCCGCTATTGCTCGTTTTGCACGAACATTATCTATTACCTTCGCTGCAGGTCTTCCTCTAGTAGAGGCAT
TGTACGCAGTTGCAGGTGCAACGGGTAATATTATTTATGCTCAAGCGACCAATAAAATTCGTGAAGAAGTTTCTAATGGT
CAACAAATACGCATTGCTATGGATAATACTCATTTATTTCCTAGTATGGTCATCCAAATGATTGCTATTGGTGAGGAGTC
CGGTGCTTTAGAGCAAATGCTGACAAAAGTTGCTGACTTTTATGAAGAAGAAGTTGATAATGCTGTAGACTCATTAAGTA
ATTTGCTTGAACCAATTATTATGTCGATATTAGGAATTTTAGTTGGCGGTTTAGTTATTGCAATGTATTTACCTATTTTT
AAACTCGGTTCCGTAGTCTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

73.645

100

0.736
  pilC Pseudomonas stutzeri DSM 10701

55.721

99.015

0.552
  pilC Acinetobacter baumannii D1279779

52.764

98.03

0.517
  pilC Acinetobacter baylyi ADP1

52.393

97.783

0.512
  pilG Neisseria meningitidis 44/76-A

45.316

97.291

0.441
  pilG Neisseria gonorrhoeae MS11

44.81

97.291

0.436
  pilC Vibrio cholerae strain A1552

43.434

97.537

0.424
  pilC Vibrio campbellii strain DS40M4

41.058

97.783

0.401

Multiple sequence alignment