Detailed information NTG1095825

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: ACMX77_RS18840
• Genome accession: NZ_CP180438
• Coordinates: 3575466..3576059 (+)
• Length: 197 a.a.
• NCBI ID: WP_003228214.1
• Uniprot ID: A0A199WEF2
• Organism: Bacillus subtilis strain W-2
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3570466..3581059

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACMX77_RS18810 (ACMX77_18810)	aspP	3571439..3573001 (+)	1563	WP_003228228.1	aspartate/proton symporter AspP	-
ACMX77_RS18815 (ACMX77_18815)	-	3573095..3573679 (+)	585	WP_047183233.1	TetR family transcriptional regulator	-
ACMX77_RS18820 (ACMX77_18820)	psmA	3573761..3574096 (+)	336	WP_014480966.1	SMR family transporter	-
ACMX77_RS18825 (ACMX77_18825)	psmB	3574096..3574416 (+)	321	WP_021480661.1	QacE family quaternary ammonium compound efflux SMR transporter	-
ACMX77_RS18830 (ACMX77_18830)	yvdQ	3574452..3574964 (-)	513	WP_015384719.1	DUF3231 family protein	-
ACMX77_RS18840 (ACMX77_18840)	clpP	3575466..3576059 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
ACMX77_RS18845 (ACMX77_18845)	pgmB	3576122..3576796 (-)	675	WP_047183234.1	beta-phosphoglucomutase	-
ACMX77_RS18850 (ACMX77_18850)	malL	3576793..3578478 (-)	1686	WP_015483736.1	oligo-1,6-glucosidase	-
ACMX77_RS18855 (ACMX77_18855)	mdxK	3578471..3580744 (-)	2274	WP_047183236.1	maltose phosphorylase	-

Sequence

Protein

• Length: 197 a.a.
• Molecular weight: 21682.00 Da
• Isoelectric Point: 4.9416

>NTDB_id=1095825 ACMX77_RS18840 WP_003228214.1 3575466..3576059(+) (clpP) [Bacillus subtilis strain W-2]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ
PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

• Length: 594 bp

>NTDB_id=1095825 ACMX77_RS18840 WP_003228214.1 3575466..3576059(+) (clpP) [Bacillus subtilis strain W-2]
ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGGGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA
TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG
AAGATCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC
ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGCATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG
CGAAAAAGGCAAACGCTATGCGCTTCCAAACAGTGAAGTCATGATTCACCAGCCACTTGGCGGTGCGCAAGGTCAGGCGA
CAGAAATTGAAATTGCCGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTTGCTGAACGTACTGGCCAG
CCGCTTGAAGTGATCGAACGCGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA
CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A199WEF2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538